(16 nodes) 2-Oxocarboxylic acid metabolism network (Caenorhabditis briggsae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bcat-1	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (414 aa)
	idhg-2	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (368 aa)
	CBG04059	Protein CBG04059. (504 aa)
	got-2.2	Aspartate aminotransferase. (414 aa)
	CBG05537	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (389 aa)
	idha-1	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (360 aa)
	idhb-1	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (379 aa)
	got-1.2	Aspartate aminotransferase. (408 aa)
	Cbr-got-1.3	Protein CBR-GOT-1.3. (397 aa)
	aco-1	Protein CBR-ACO-1; Belongs to the aconitase/IPM isomerase family. (909 aa)
	idh-2	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (435 aa)
	CBG17687	Protein CBG17687. (411 aa)
	idhg-1	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (396 aa)
	idh-1	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (413 aa)
	aco-2	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (777 aa)
	cts-1	Probable citrate synthase, mitochondrial. (468 aa)

Your Current Organism:

Caenorhabditis briggsae

NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBG04059	CBG05537	A8WW42	A8X039	Protein CBG04059.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.543
CBG04059	CBG17687	A8WW42	A8XRI5	Protein CBG04059.	Protein CBG17687.	0.457
CBG04059	Cbr-got-1.3	A8WW42	A8XNT7	Protein CBG04059.	Protein CBR-GOT-1.3.	0.965
CBG04059	bcat-1	A8WW42	A8WM75	Protein CBG04059.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.543
CBG04059	cts-1	A8WW42	Q61JF9	Protein CBG04059.	Probable citrate synthase, mitochondrial.	0.510
CBG04059	got-1.2	A8WW42	A8XNT6	Protein CBG04059.	Aspartate aminotransferase.	0.965
CBG04059	got-2.2	A8WW42	A8WYZ3	Protein CBG04059.	Aspartate aminotransferase.	0.991
CBG04059	idh-1	A8WW42	A8Y0T7	Protein CBG04059.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.868
CBG04059	idh-2	A8WW42	A8XQZ0	Protein CBG04059.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.868
CBG04059	idha-1	A8WW42	A8XFX3	Protein CBG04059.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.849
CBG04059	idhb-1	A8WW42	A8XNQ1	Protein CBG04059.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.849
CBG04059	idhg-1	A8WW42	A8XSW4	Protein CBG04059.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.849
CBG04059	idhg-2	A8WW42	A8WVT2	Protein CBG04059.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.849
CBG05537	CBG04059	A8X039	A8WW42	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Protein CBG04059.	0.543
CBG05537	bcat-1	A8X039	A8WM75	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.988
CBG05537	cts-1	A8X039	Q61JF9	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Probable citrate synthase, mitochondrial.	0.412
CBG05537	idh-1	A8X039	A8Y0T7	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.499
CBG05537	idh-2	A8X039	A8XQZ0	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.499
CBG05537	idha-1	A8X039	A8XFX3	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.421
CBG05537	idhb-1	A8X039	A8XNQ1	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.421