STRINGSTRING
fat-5 fat-5 haf-1 haf-1 parp-2 parp-2 clpp-1 clpp-1 smk-1 smk-1 pmk-1 pmk-1 pmk-2 pmk-2 pmk-3 pmk-3 gst-36 gst-36 fard-1 fard-1 gcs-1 gcs-1 lgg-1 lgg-1 gst-9 gst-9 gst-4 gst-4 CBG04233 CBG04233 daf-12 daf-12 pha-4 pha-4 fat-6 fat-6 par-5 par-5 jnk-1 jnk-1 atf-5 atf-5 CBG08151 CBG08151 hsp-6 hsp-6 daf-36 daf-36 CBG10201 CBG10201 tcer-1 tcer-1 hsp-60 hsp-60 daf-16 daf-16 let-363 let-363 sod-2 sod-2 rsks-1 rsks-1 hsb-1 hsb-1 kgb-1 kgb-1 daf-18 daf-18 jkk-1 jkk-1 ubl-5 ubl-5 timm-23 timm-23 gsto-3.2 gsto-3.2 nhr-80 nhr-80 daf-2 daf-2 sek-1 sek-1 CBG17045 CBG17045 ftt-2 ftt-2 vhl-1 vhl-1 hcf-1 hcf-1 sip-1 sip-1 gsto-2 gsto-2 lipl-4 lipl-4 mtl-1 mtl-1 CBG19185 CBG19185 hsp-16.2 hsp-16.2 skn-1 skn-1 gst-39 gst-39 gst-24 gst-24 gst-20 gst-20 ddl-2 ddl-2 ctl-1 ctl-1 ctl-2 ctl-2 CBG21702 CBG21702 hsp-12.6 hsp-12.6 gsto-1.2 gsto-1.2 age-1 age-1 sir-2.1 sir-2.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fat-5Protein CBR-FAT-5; Belongs to the fatty acid desaturase type 1 family. (333 aa)
haf-1Protein CBR-HAF-1. (699 aa)
parp-2Poly [ADP-ribose] polymerase. (531 aa)
clpp-1ATP-dependent Clp protease proteolytic subunit 1, mitochondrial; Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates (By similarity); Belongs to the peptidase S14 family. (219 aa)
smk-1Protein CBR-SMK-1. (1124 aa)
pmk-1Mitogen-activated protein kinase. (377 aa)
pmk-2Mitogen-activated protein kinase. (392 aa)
pmk-3Mitogen-activated protein kinase. (466 aa)
gst-36Protein CBR-GST-36; Belongs to the GST superfamily. (210 aa)
fard-1Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (555 aa)
gcs-1Protein CBR-GCS-1. (654 aa)
lgg-1Protein lgg. (123 aa)
gst-9Protein CBR-GST-9. (206 aa)
gst-4Protein CBR-GST-4; Belongs to the GST superfamily. (207 aa)
CBG04233Protein CBG04233; Belongs to the GST superfamily. (212 aa)
daf-12Protein CBR-DAF-12. (758 aa)
pha-4Protein CBR-PHA-4. (477 aa)
fat-6Protein CBR-FAT-6; Belongs to the fatty acid desaturase type 1 family. (338 aa)
par-5Protein CBR-PAR-5; Belongs to the 14-3-3 family. (248 aa)
jnk-1Mitogen-activated protein kinase. (464 aa)
atf-5Protein CBR-ATF-5. (233 aa)
CBG08151Protein CBG08151; Belongs to the protein kinase superfamily. (401 aa)
hsp-6Protein CBR-HSP-6; Belongs to the heat shock protein 70 family. (658 aa)
daf-36Protein CBR-DAF-36. (430 aa)
CBG10201Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (370 aa)
tcer-1Protein CBR-TCER-1. (920 aa)
hsp-60Protein CBR-HSP-60; Belongs to the chaperonin (HSP60) family. (567 aa)
daf-16Protein CBR-DAF-16. (497 aa)
let-363Serine/threonine-protein kinase TOR. (1721 aa)
sod-2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (223 aa)
rsks-1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (540 aa)
hsb-1Protein CBR-HSB-1. (86 aa)
kgb-1Mitogen-activated protein kinase. (382 aa)
daf-18Protein CBR-DAF-18. (992 aa)
jkk-1Protein CBR-JKK-1. (435 aa)
ubl-5Protein CBR-UBL-5. (73 aa)
timm-23Protein CBG15355. (243 aa)
gsto-3.2Protein CBR-GSTO-3; Belongs to the GST superfamily. (643 aa)
nhr-80Protein CBR-NHR-80. (489 aa)
daf-2Protein CBR-DAF-2. (1840 aa)
sek-1Protein CBR-SEK-1; Belongs to the protein kinase superfamily. (352 aa)
CBG17045Protein CBG17045; Belongs to the fatty acid desaturase type 1 family. (338 aa)
ftt-2Protein CBR-FTT-2; Belongs to the 14-3-3 family. (248 aa)
vhl-1Protein CBR-VHL-1. (170 aa)
hcf-1Protein CBR-HCF-1. (771 aa)
sip-1Protein CBR-SIP-1; Belongs to the small heat shock protein (HSP20) family. (161 aa)
gsto-2Probable glutathione transferase omega-2; Exhibits glutathione-dependent thiol transferase activity. Has dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) (By similarity); Belongs to the GST superfamily. Omega family. (253 aa)
lipl-4Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (423 aa)
mtl-1Protein CBR-MTL-1. (72 aa)
CBG19185Protein CBG19185; Belongs to the small heat shock protein (HSP20) family. (143 aa)
hsp-16.2Protein CBG19186; Belongs to the small heat shock protein (HSP20) family. (146 aa)
skn-1Protein CBR-SKN-1. (611 aa)
gst-39Protein CBR-GST-39; Belongs to the GST superfamily. (209 aa)
gst-24Protein CBR-GST-24; Belongs to the GST superfamily. (216 aa)
gst-20Protein CBR-GST-20. (208 aa)
ddl-2Protein CBR-DDL-2. (495 aa)
ctl-1Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (547 aa)
ctl-2Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (500 aa)
CBG21702Protein CBG21702. (95 aa)
hsp-12.6Protein CBR-HSP-12.6; Belongs to the small heat shock protein (HSP20) family. (110 aa)
gsto-1.2Protein CBR-GSTO-1.1; Belongs to the GST superfamily. (250 aa)
age-1Phosphatidylinositol 3-kinase age-1; Phosphatidylinositol 3-kinase homolog that regulates longevity and diapause. Promotes cell survival during embryonic development by recruiting akt-1/2 to the plasma membrane through the production of PtdIns(3,4,5)P3. Could function in the development or neuroendocrine signaling of the dauer pathway. Mediates susceptibility to enteropathogenic E.coli infection. May negatively regulate AYI interneuron neurite outgrowth. Plays a role in aversive olfactory learning when an odor is associated with food deprivation. Regulates this process by promoting the [...] (1159 aa)
sir-2.1NAD-dependent protein deacetylase sir-2.1; NAD-dependent deacetylase. Required for a reduction of the 'Lys-16' acetylation of histone H4 (H4K16ac) on dosage-compensated X chromosomes in hermaphrodites. Functions upstream of daf-16 in the insulin-like signaling pathway, promoting daf-16 mediated transcriptional activation and increased life-span. May also regulate life-span independently of daf-16 by modulating the transcription of genes involved in the stress response of the endoplasmic reticulum (ER). Acts upstream of the nicotinic acid metabolism pathway, which may be linked to the r [...] (602 aa)
Your Current Organism:
Caenorhabditis briggsae
NCBI taxonomy Id: 6238
Other names: C. briggsae, Caenorhabditis briggsae AF16
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