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| | C03B1.5 | Putative tyrosine-protein kinase C03B1.5. (328 aa) |
| | mel-11 | ANK_REP_REGION domain-containing protein. (1124 aa) |
| | C07H6.2 | Uncharacterized protein. (107 aa) |
| | pptr-2 | Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (607 aa) |
| | ccm-3 | Programmed cell death protein 10 homolog; Involved in excretory canal elongation during postembryonic development. Plays a role in promoting Golgi stability, ER integrity and vesicle transport probably by regulating the activation of Rho GTPase cdc-42. Involved in fertility. (215 aa) |
| | C14B1.8 | Uncharacterized protein. (231 aa) |
| | C18C4.7 | Uncharacterized protein. (1348 aa) |
| | frm-4 | FERM domain-containing protein. (672 aa) |
| | cst-2 | Protein kinase domain-containing protein. (421 aa) |
| | C24H11.2 | Serine/threonine-protein phosphatase. (384 aa) |
| | rsa-1 | Serine/threonine-protein phosphatase 2A regulatory subunit rsa-1; Regulatory subunit of phosphatase let-92 which recruits let- 92/paa-1 complex to the centrosomes, thereby regulating microtubule outgrowth from centrosomes and mitotic spindle assembly ensuring the stability of kinetochore microtubules. (404 aa) |
| | mob-4 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. (223 aa) |
| | C30A5.4 | Uncharacterized protein C30A5.4. (378 aa) |
| | tbck-1 | TBC Kinase homolog. (841 aa) |
| | max-1 | Motor AXon guidance. (1099 aa) |
| | pph-6 | Serine/threonine-protein phosphatase 6 catalytic subunit; Catalytic subunit of protein phosphatase 6 (PP6) (By similarity). In complex with saps-1, promotes actomyosin contractility during cytokinesis by regulating the organization of cortical non- muscle myosin II nmy-2 and thus contributing to correct spindle positioning. Also required for the proper generation of pulling forces on spindle poles during anaphase by regulating the cortical localization of gpr-1, gpr-2 and lin-5. Belongs to the PPP phosphatase family. PP-6 (PP-V) subfamily. (331 aa) |
| | maph-1.3 | Microtubule-Associated Protein Homolog. (874 aa) |
| | saps-1 | Serine/threonine-protein phosphatase 6 regulatory subunit; Regulatory subunit of protein phosphatase 6 (PP6) (Probable). In complex with pph-6, promotes actomyosin contractility during cytokinesis by regulating the organization of cortical non-muscle myosin II nmy-2 and thus contributing to correct spindle positioning. Also required for the proper generation of pulling forces on spindle poles during anaphase by regulating the cortical localization of gpr-1, gpr-2 and lin-5. Negatively regulates kinase air-1 localization at the cell cortex ; Belongs to the SAPS family. (778 aa) |
| | C49H3.6 | CortBP2 domain-containing protein. (552 aa) |
| | C50F7.6 | Uncharacterized protein. (418 aa) |
| | CC8.2 | Protein phosphatase 1 regulatory subunit. (318 aa) |
| | ppfr-2 | Protein Phosphatase Four Regulatory subunit. (378 aa) |
| | mob-2 | Mps One Binder (Mats/MOB1) homolog. (350 aa) |
| | farl-11 | DUF3402 domain-containing protein. (978 aa) |
| | F13B12.6 | SH2 domain-containing protein. (537 aa) |
| | yap-1 | Yes-associated protein homolog 1; Plays a role in thermal stress response and in aging. (442 aa) |
| | cst-1 | Serine/threonine-protein kinase cst-1 18kDa subunit; Serine/threonine-protein kinase which extends lifespan and delays tissue aging, probably by activating daf-16. (497 aa) |
| | ppfr-1 | Serine/threonine-protein phosphatase 4 regulatory subunit 1; Probable regulatory subunit of serine/threonine-protein phosphatase PP4 which may play a role in meiosis and embryonic mitosis. Probably in association with catalytic subunit pph-4.1, regulates microtubule severing during oocyte meiosis II by dephosphorylating and likely activating mei-1, a component of the katanin microtubule severing complex. (1562 aa) |
| | snx-17 | Sorting nexin-17 homolog; Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)). (540 aa) |
| | F18C12.3 | Uncharacterized protein. (545 aa) |
| | sax-2 | Sensory AXon guidance. (2886 aa) |
| | F22D6.9 | Serine/threonine-protein phosphatase. (368 aa) |
| | F25B3.4 | Serine/threonine-protein phosphatase. (363 aa) |
| | maph-1.2 | Microtubule-Associated Protein Homolog. (874 aa) |
| | frm-10 | FERM domain-containing protein. (504 aa) |
| | F26B1.5 | Serine/threonine-protein phosphatase. (383 aa) |
| | sur-6 | Serine/threonine-protein phosphatase 2A regulatory subunit sur-6; Probable regulatory subunit of serine/threonine phosphatase let-92. Together with let-92 and constant regulatory subunit paa-1, positively regulates centriole duplication during early embryonic cell divisions by preventing the degradation of sas-5 and kinase zyg-1. In addition, during vulva development, may play a role with phosphatase let-92 and regulatory subunit paa-1 in the induction of vulva cell precursors by positively regulating let-60/Ras- MAP kinase signaling, probably by promoting lin-45 activation. In intesti [...] (495 aa) |
| | F28C1.3 | Protein phosphatase 1 regulatory subunit 37 homolog. (944 aa) |
| | gsp-1 | Serine/threonine-protein phosphatase PP1-alpha; Serine/threonine-protein phosphatase which antagonizes the function of air-2 in the regulation of chromosome cohesion. Dephosphorylates histone H3 at 'Ser-10'. Dephosphorylates translation initiation factor eIF2alpha. Involved in the activation of chloride channel clh-3 during cell swelling and meiotic maturation. Belongs to the PPP phosphatase family. PP-1 subfamily. (329 aa) |
| | frm-9 | FERM domain (Protein4.1-ezrin-radixin-moesin) family. (1627 aa) |
| | maph-1.1 | Microtubule-associated protein homolog maph-1.1; Belongs to the MAP1A/MAP1B/MAP1S family. (878 aa) |
| | mob-1 | Mps One Binder (Mats/MOB1) homolog. (193 aa) |
| | let-92 | Serine/threonine-protein phosphatase 2A catalytic subunit; Protein phosphatase which plays an essential role in early embryonic cell division. Probably together with constant regulatory subunit paa-1 and regulatory subunit sur-6, positively regulates centriole duplication by preventing the degradation of sas-5 and kinase zyg-1. In addition, plays a role in the recruitment of sas- 6 and maybe sas-5 to centrioles and may dephosphorylate sas-5 and zyg-1 negative regulator szy-20. During vulva development, may play a role with regulatory subunits paa-1 and sur-6 in the induction of vulva c [...] (318 aa) |
| | F40E3.5 | SER_THR_PHOSPHATASE domain-containing protein. (344 aa) |
| | smk-1 | SMK-1 domain-containing protein. (1085 aa) |
| | nfm-1 | FERM domain-containing protein. (709 aa) |
| | F43B10.1 | Uncharacterized protein. (1325 aa) |
| | F43E2.6 | Uncharacterized protein. (104 aa) |
| | F44B9.9 | Uncharacterized protein F44B9.9. (244 aa) |
| | F46C5.6 | Uncharacterized protein. (945 aa) |
| | ape-1 | Apoptotic enhancer 1 protein; Negetively regulates apoptosis via its interaction with cep- 1. (769 aa) |
| | paa-1 | Probable serine/threonine-protein phosphatase PP2A regulatory subunit; Acts as a scaffolding protein for phosphatase let-92 and its regulatory subunits (Probable). Probably together with let-92 and regulatory subunit sur-6, regulates centriole duplication, microtubule outgrowth and mitotic spindle stability during early embryonic cell division by preventing the degradation of sas-5 and kinase zyg-1. During vulva development, may play a role with phosphatase let-92 and regulatory subunit sur-6 in the induction of vulva cell precursors by positively regulating let-60/Ras- MAP kinase sign [...] (590 aa) |
| | klf-2 | Kruppel-Like Factor (Zinc finger protein). (299 aa) |
| | F55C10.5 | Uncharacterized protein. (112 aa) |
| | frm-3 | FERM domain-containing protein. (1091 aa) |
| | frm-8 | FERM domain (Protein4.1-ezrin-radixin-moesin) family. (853 aa) |
| | H18N23.2 | Protein phosphatase 1 regulatory subunit. (368 aa) |
| | K05B2.2 | Uncharacterized protein. (319 aa) |
| | K07A9.3 | CCM (Cerebral Cavernous Malformation) gene homolog. (255 aa) |
| | cash-1 | WD_REPEATS_REGION domain-containing protein. (678 aa) |
| | K10D2.8 | Uncharacterized protein. (335 aa) |
| | cnk-1 | Connector enhancer of kinase suppressor of ras; Non-essential component of the Ras signaling pathway. (801 aa) |
| | srx-2 | 7TM_GPCR_Srx domain-containing protein. (335 aa) |
| | sax-1 | Serine/threonine-protein kinase sax-1; Acts with sax-2 to restrict the growth of both primary and secondary neurites. Regulates mechanosensory tiling by controlling the termination point of sensory dendrites; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (476 aa) |
| | T05H4.3 | Uncharacterized protein. (1150 aa) |
| | T09A5.15 | Uncharacterized protein. (92 aa) |
| | sav-1 | SAlVador (Cell proliferation regulator) homolog. (389 aa) |
| | mob-3 | Mps One Binder (Mats/MOB1) homolog. (292 aa) |
| | gck-1 | Germinal center kinase 1; Serine/threonine-protein kinase which is required for normal oogenesis and suppression of germline cell apoptosis. Inhibits phosphorylation and thus probably activation of mpk-1 during pachytene stage. Involved in excretory canal elongation during postembryonic development, probably acting downstream of ccm-3 ; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (803 aa) |
| | wts-1 | Serine/threonine-protein kinase WARTS homolog; Phosphorylates yap-1 which may negatively regulate yap-1 nuclear localization. Plays an essential role in larval development. Regulates growth, the formation of gut granules, lifespan and cell and body sizes probably in synergy with the TGF-beta sma/mab pathway. Does not appear to regulate apoptosis and proliferation. In addition, may synergize with the TGF-beta daf-7 dauer pathway to regulate entry into the dauer stage. Maintains the cellular integrity of intestinal cells by regulating the localization of apical actin and junctional proteins. (908 aa) |
| | unc-49 | Ionotropic GABA receptor subunit UNC-49B.3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (506 aa) |
| | T24D5.4 | Protein kinase domain-containing protein. (89 aa) |
| | rsf-1 | RASSF (Ras-association domain family) homolog. (615 aa) |
| | W03D8.2 | Serine/threonine-protein phosphatase. (364 aa) |
| | pptr-1 | Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1; Probable regulatory subunit of serine/threonine-protein phosphatase let-92 which negatively regulates the insulin receptor signaling cascade composed of daf-2, age-1, akt-1, akt-2 and sgk-1 by promoting the dephosphorylation of akt-1 on 'Thr-350'. Negatively regulates several functions controlled by the insulin pathway including dauer formation, lifespan, fat storage and stress resistance. Plays a role in the asymmetric segregation of the P granule components during embryonic cell divisions but does not play an essentia [...] (542 aa) |
| | Y106G6A.1 | Protein kinase domain-containing protein. (430 aa) |
| | szy-2 | Suppressor of ZYg-1. (193 aa) |
| | frm-5.2 | FERM domain (Protein4.1-ezrin-radixin-moesin) family. (1352 aa) |
| | frm-5.1 | FERM domain (Protein4.1-ezrin-radixin-moesin) family. (1565 aa) |
| | Y45F10D.10 | Integrin Cytoplasmic domain-Associated Protein homolog. (157 aa) |
| | pph-4.2 | Serine/threonine-protein phosphatase 4 catalytic subunit 2; Protein phosphatase which seems to be involved in larval development but not essential for embryogenesis. (321 aa) |
| | Y65A5A.2 | Uncharacterized protein. (333 aa) |
| | Y69E1A.4 | Serine/threonine-protein phosphatase. (375 aa) |
| | Y71G12B.30 | Serine/threonine-protein phosphatase. (333 aa) |
| | Y71H2AM.20 | Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (375 aa) |
| | ppfr-4 | Serine/threonine-protein phosphatase 4 regulatory subunit ppfr-4; Probable regulatory subunit of serine/threonine-protein phosphatase PP4 which may play a role in meiosis and embryonic mitosis. Probably in association with catalytic subunit pph-4.1, regulates microtubule severing during oocyte meiosis II by dephosphorylating and likely activating mei-1, a component of the katanin microtubule severing complex. (327 aa) |
| | pph-4.1 | Serine/threonine-protein phosphatase 4 catalytic subunit 1; Protein phosphatase which plays an essential role in meiosis and in early embryonic mitosis. During spermatocyte meiosis and the first embryonic mitosis, regulates centrosome maturation, and thus spindle formation, by recruiting some of the components of the pericentriolar material (PCM). During oocyte meiosis I, regulates meiotic chromosome dynamics including synapsis-independent chromosome pairing, restriction of synapsis to homologous chromosomes, programmed DNA double-strand break initiation and crossover formation resulti [...] (333 aa) |
| | Y81G3A.4 | Uncharacterized protein. (264 aa) |
| | kri-1 | KRIT 1 (Krev interaction trapped/cerebral cavernous malformation 1) homolog. (729 aa) |
| | ZK354.9 | Serine/threonine-protein phosphatase. (296 aa) |
| | ZK637.2 | Uncharacterized protein ZK637.2; Belongs to the FAM136 family. (143 aa) |
| | tag-307 | ApaG domain-containing protein. (342 aa) |
| | ZK688.11 | Uncharacterized protein. (168 aa) |
| | ZK688.9 | TIP41-like protein; Belongs to the TIP41 family. (281 aa) |
| | ZK945.8 | Uncharacterized protein ZK945.8. (109 aa) |
