STRINGSTRING
4R79.2 4R79.2 ggtb-1 ggtb-1 ssr-2 ssr-2 sec-15 sec-15 sec-10 sec-10 rab-1 rab-1 exoc-7 exoc-7 C49F8.3 C49F8.3 C56E6.2 C56E6.2 rab-8 rab-8 rab-39 rab-39 sec-6 sec-6 F11A5.3 F11A5.3 F11A5.4 F11A5.4 alfa-1 alfa-1 hum-2 hum-2 src-2 src-2 sec-3 sec-3 rab-11.1 rab-11.1 F54C9.11 F54C9.11 rfip-1 rfip-1 rab-14 rab-14 M57.2 M57.2 smcr-8 smcr-8 T04C9.1 T04C9.1 sec-5 sec-5 rab-37 rab-37 rab-11.2 rab-11.2 exoc-8 exoc-8 sec-8 sec-8 tbc-17 tbc-17 gdi-1 gdi-1 rab-19 rab-19 rep-1 rep-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
4R79.2Uncharacterized protein. (395 aa)
ggtb-1Probable geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal. (335 aa)
ssr-2Sperm-Specific family, class R. (320 aa)
sec-15Exocyst complex component 6; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC15 family. (817 aa)
sec-10Exocyst complex component 5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC10 family. (704 aa)
rab-1RAB family. (205 aa)
exoc-7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (630 aa)
C49F8.3DB domain-containing protein. (176 aa)
C56E6.2Uncharacterized protein. (266 aa)
rab-8RAB family. (211 aa)
rab-39RAB family. (229 aa)
sec-6Exocyst complex component 3; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC6 family. (796 aa)
F11A5.3Uncharacterized protein. (201 aa)
F11A5.4Uncharacterized protein. (203 aa)
alfa-1ALS/FTD Associated gene homolog. (734 aa)
hum-2Dilute domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1811 aa)
src-2Tyrosine protein-kinase src-2; Non-receptor tyrosine-protein kinase which may play a role in larval and pharynx development. Unlike src-1, does not play a role in embryonic development. (507 aa)
sec-3Exocyst complex component 1; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (848 aa)
rab-11.1Ras-related protein rab-11.1; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Involved in regulating the meiotic maturation of oocytes. Plays a role in egg shell formation, regulating exocytosis of chondroitin proteoglycans following fertilization. Controls cor [...] (211 aa)
F54C9.11Uncharacterized protein. (367 aa)
rfip-1FIP-RBD domain-containing protein. (471 aa)
rab-14RAB family. (210 aa)
M57.2Uncharacterized protein. (580 aa)
smcr-8Guanine nucleotide exchange protein smcr-8; Part of a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy; Belongs to the SMCR8 family. (511 aa)
T04C9.1Uncharacterized protein. (881 aa)
sec-5Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (884 aa)
rab-37RAB family. (223 aa)
rab-11.2RAB family. (198 aa)
exoc-8Exo84_C domain-containing protein. (686 aa)
sec-8Exocyst complex component 4; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (893 aa)
tbc-17Rab-GAP TBC domain-containing protein. (1073 aa)
gdi-1Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (459 aa)
rab-19RAB family. (210 aa)
rep-1Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (510 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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