5 items (Caenorhabditis elegans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	elf-1	ETS domain-containing protein. (420 aa)
	ets-9	ETS domain-containing protein. (396 aa)
	F19F10.1	ETS domain-containing protein. (210 aa)
	nhr-265	Nuclear Hormone Receptor family. (348 aa)
	nhr-119	Nuclear Hormone Receptor family. (708 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F19F10.1	elf-1	F19F10.1.2	C24A1.2a.1	ETS domain-containing protein.	ETS domain-containing protein.	0.444
F19F10.1	ets-9	F19F10.1.2	C52B9.2b.2	ETS domain-containing protein.	ETS domain-containing protein.	0.806
elf-1	F19F10.1	C24A1.2a.1	F19F10.1.2	ETS domain-containing protein.	ETS domain-containing protein.	0.444
elf-1	ets-9	C24A1.2a.1	C52B9.2b.2	ETS domain-containing protein.	ETS domain-containing protein.	0.843
ets-9	F19F10.1	C52B9.2b.2	F19F10.1.2	ETS domain-containing protein.	ETS domain-containing protein.	0.806
ets-9	elf-1	C52B9.2b.2	C24A1.2a.1	ETS domain-containing protein.	ETS domain-containing protein.	0.843
ets-9	nhr-119	C52B9.2b.2	K12H6.1.1	ETS domain-containing protein.	Nuclear Hormone Receptor family.	0.811
ets-9	nhr-265	C52B9.2b.2	F41D3.3.1	ETS domain-containing protein.	Nuclear Hormone Receptor family.	0.747
nhr-119	ets-9	K12H6.1.1	C52B9.2b.2	Nuclear Hormone Receptor family.	ETS domain-containing protein.	0.811
nhr-119	nhr-265	K12H6.1.1	F41D3.3.1	Nuclear Hormone Receptor family.	Nuclear Hormone Receptor family.	0.810
nhr-265	ets-9	F41D3.3.1	C52B9.2b.2	Nuclear Hormone Receptor family.	ETS domain-containing protein.	0.747
nhr-265	nhr-119	F41D3.3.1	K12H6.1.1	Nuclear Hormone Receptor family.	Nuclear Hormone Receptor family.	0.810