STRINGSTRING
cpr-1 cpr-1 asp-5 asp-5 asp-6 asp-6 tag-196 tag-196 F57F5.1 F57F5.1 asp-3 asp-3 asp-14 asp-14 K12H4.7 K12H4.7 asp-4 asp-4 asp-2 asp-2 cpr-5 cpr-5 asp-1 asp-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cpr-1Gut-specific cysteine proteinase; Thiol protease. Has a role as a digestive enzyme. Belongs to the peptidase C1 family. (329 aa)
asp-5Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (393 aa)
asp-6Aspartic protease 6; Aspartic protease; Belongs to the peptidase A1 family. (389 aa)
tag-196Uncharacterized protein; Belongs to the peptidase C1 family. (477 aa)
F57F5.1Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (351 aa)
asp-3Aspartic protease 3; Aspartic protease (Probable). Part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. (398 aa)
asp-14Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (366 aa)
K12H4.7Putative serine protease K12H4.7. (510 aa)
asp-4Aspartic protease 4; Aspartic protease, which is part of the necrosis cell death pathway. Involved in neuronal cell degeneration. Involved in heat stress response. Belongs to the peptidase A1 family. (444 aa)
asp-2Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (429 aa)
cpr-5Cathepsin B-like cysteine proteinase 5; Belongs to the peptidase C1 family. (344 aa)
asp-1Aspartic protease 1; Aspartic protease, which is part of the necrosis cell death pathway. Promotes B.thuringiensis Cry6Aa stability by preventing its proteolysis by host gut proteases. Required for Cry6Aa-induced necrotic death of intestinal cells. Cry6Aa uptake into the host intestinal cells triggers an increase in intracellular Ca(2+) levels leading to lysosome rupture and to the subsequent release of asp-1 which leads to necrosis ; Belongs to the peptidase A1 family. (396 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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