Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| F07B7.12 | dlk-1 | F07B7.12.1 | F33E2.2a.1 | Uncharacterized protein. | Mitogen-activated protein kinase kinase kinase dlk-1; Component of a MAP kinase pathway that functions presynaptically to regulate synaptic architecture and presynaptic differentiation. Phosphorylates and activates mkk-4. Has a role in axonal regrowth following injury and synaptogenesis. Also promotes tubulin post-translational modifications that protect microtubules. Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis, and may also have a role in intraflagellar transport in cilia. Plays a role in the formation of muscle connections, also called mu [...] | 0.940 |
| F07B7.12 | fsn-1 | F07B7.12.1 | C26E6.5.1 | Uncharacterized protein. | F-box/SPRY domain-containing protein 1; Component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which is required for the restriction and/or maturation of synapses in GABAergic neuromuscular junction (NMJ) presynaptic neurons. Promotes NRJ synapse development and synaptic transmission by negatively regulating the daf- 2/InsR pathway in muscles. By targeting convertase egl-3 for degradation, negatively modulates insulin-like protein ins-4 and ins-6 processing. May stabilize synapse formation by promoting the down-regulation of scd-2. Regulates axon termination in PLM an [...] | 0.783 |
| F07B7.12 | lpd-3 | F07B7.12.1 | Y47G6A.23d.1 | Uncharacterized protein. | FSA_C domain-containing protein. | 0.404 |
| F07B7.12 | rpm-1 | F07B7.12.1 | C01B7.6.1 | Uncharacterized protein. | E3 ubiquitin-protein ligase rpm-1; Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating lysine residues (By similarity). Shows esterification activity towards both threonine and serine, with a preference for threonine, and acts via two essential catalytic cysteine residues that relay ubiquitin to its substrate via thioester intermediates (By similarity). Mediates ubiquitination and subsequent proteasomal degradation of target proteins, including dlk-1. Negatively regulates a p38 MA [...] | 0.900 |
| F23F1.6 | glo-1 | F23F1.6.1 | R07B1.12.1 | AA_permease_C domain-containing protein. | Gut granule LOss. | 0.490 |
| F23F1.6 | glo-4 | F23F1.6.1 | F07C3.4.1 | AA_permease_C domain-containing protein. | X-linked retinitis pigmentosa GTPase regulator homolog; Could be a guanine-nucleotide releasing factor for glo-1. May play a role in gut granule biogenesis. Regulates axon termination in PLM and ALM neurons. | 0.569 |
| F23F1.6 | lpd-3 | F23F1.6.1 | Y47G6A.23d.1 | AA_permease_C domain-containing protein. | FSA_C domain-containing protein. | 0.810 |
| F23F1.6 | pgp-2 | F23F1.6.1 | C34G6.4b.1 | AA_permease_C domain-containing protein. | p-GlycoProtein related. | 0.508 |
| F23F1.6 | rbg-3 | F23F1.6.1 | B0393.2.2 | AA_permease_C domain-containing protein. | Rab-GAP TBC domain-containing protein. | 0.850 |
| F23F1.6 | tub-1 | F23F1.6.1 | F10B5.4.1 | AA_permease_C domain-containing protein. | Tubby protein homolog 1; Has a role in fat regulation independent of daf-16. Implicated in ciliar sensory function which is required for normal sensory behavior such as chemotaxis. Functions in life span control via the insulin/IGF-1 pathway. Thought to be involved in neuronal trafficking. | 0.894 |
| cup-5 | glo-1 | R13A5.1e.2 | R07B1.12.1 | PKD_channel domain-containing protein. | Gut granule LOss. | 0.727 |
| cup-5 | glo-4 | R13A5.1e.2 | F07C3.4.1 | PKD_channel domain-containing protein. | X-linked retinitis pigmentosa GTPase regulator homolog; Could be a guanine-nucleotide releasing factor for glo-1. May play a role in gut granule biogenesis. Regulates axon termination in PLM and ALM neurons. | 0.527 |
| cup-5 | mrp-4 | R13A5.1e.2 | F21G4.2.1 | PKD_channel domain-containing protein. | Uncharacterized protein. | 0.696 |
| cutl-1 | dlk-1 | F53F1.1.1 | F33E2.2a.1 | ZP domain-containing protein. | Mitogen-activated protein kinase kinase kinase dlk-1; Component of a MAP kinase pathway that functions presynaptically to regulate synaptic architecture and presynaptic differentiation. Phosphorylates and activates mkk-4. Has a role in axonal regrowth following injury and synaptogenesis. Also promotes tubulin post-translational modifications that protect microtubules. Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis, and may also have a role in intraflagellar transport in cilia. Plays a role in the formation of muscle connections, also called mu [...] | 0.587 |
| dlk-1 | F07B7.12 | F33E2.2a.1 | F07B7.12.1 | Mitogen-activated protein kinase kinase kinase dlk-1; Component of a MAP kinase pathway that functions presynaptically to regulate synaptic architecture and presynaptic differentiation. Phosphorylates and activates mkk-4. Has a role in axonal regrowth following injury and synaptogenesis. Also promotes tubulin post-translational modifications that protect microtubules. Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis, and may also have a role in intraflagellar transport in cilia. Plays a role in the formation of muscle connections, also called mu [...] | Uncharacterized protein. | 0.940 |
| dlk-1 | cutl-1 | F33E2.2a.1 | F53F1.1.1 | Mitogen-activated protein kinase kinase kinase dlk-1; Component of a MAP kinase pathway that functions presynaptically to regulate synaptic architecture and presynaptic differentiation. Phosphorylates and activates mkk-4. Has a role in axonal regrowth following injury and synaptogenesis. Also promotes tubulin post-translational modifications that protect microtubules. Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis, and may also have a role in intraflagellar transport in cilia. Plays a role in the formation of muscle connections, also called mu [...] | ZP domain-containing protein. | 0.587 |
| dlk-1 | fsn-1 | F33E2.2a.1 | C26E6.5.1 | Mitogen-activated protein kinase kinase kinase dlk-1; Component of a MAP kinase pathway that functions presynaptically to regulate synaptic architecture and presynaptic differentiation. Phosphorylates and activates mkk-4. Has a role in axonal regrowth following injury and synaptogenesis. Also promotes tubulin post-translational modifications that protect microtubules. Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis, and may also have a role in intraflagellar transport in cilia. Plays a role in the formation of muscle connections, also called mu [...] | F-box/SPRY domain-containing protein 1; Component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which is required for the restriction and/or maturation of synapses in GABAergic neuromuscular junction (NMJ) presynaptic neurons. Promotes NRJ synapse development and synaptic transmission by negatively regulating the daf- 2/InsR pathway in muscles. By targeting convertase egl-3 for degradation, negatively modulates insulin-like protein ins-4 and ins-6 processing. May stabilize synapse formation by promoting the down-regulation of scd-2. Regulates axon termination in PLM an [...] | 0.837 |
| dlk-1 | glo-1 | F33E2.2a.1 | R07B1.12.1 | Mitogen-activated protein kinase kinase kinase dlk-1; Component of a MAP kinase pathway that functions presynaptically to regulate synaptic architecture and presynaptic differentiation. Phosphorylates and activates mkk-4. Has a role in axonal regrowth following injury and synaptogenesis. Also promotes tubulin post-translational modifications that protect microtubules. Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis, and may also have a role in intraflagellar transport in cilia. Plays a role in the formation of muscle connections, also called mu [...] | Gut granule LOss. | 0.424 |
| dlk-1 | glo-4 | F33E2.2a.1 | F07C3.4.1 | Mitogen-activated protein kinase kinase kinase dlk-1; Component of a MAP kinase pathway that functions presynaptically to regulate synaptic architecture and presynaptic differentiation. Phosphorylates and activates mkk-4. Has a role in axonal regrowth following injury and synaptogenesis. Also promotes tubulin post-translational modifications that protect microtubules. Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis, and may also have a role in intraflagellar transport in cilia. Plays a role in the formation of muscle connections, also called mu [...] | X-linked retinitis pigmentosa GTPase regulator homolog; Could be a guanine-nucleotide releasing factor for glo-1. May play a role in gut granule biogenesis. Regulates axon termination in PLM and ALM neurons. | 0.809 |
| dlk-1 | rpm-1 | F33E2.2a.1 | C01B7.6.1 | Mitogen-activated protein kinase kinase kinase dlk-1; Component of a MAP kinase pathway that functions presynaptically to regulate synaptic architecture and presynaptic differentiation. Phosphorylates and activates mkk-4. Has a role in axonal regrowth following injury and synaptogenesis. Also promotes tubulin post-translational modifications that protect microtubules. Plays a role in cilium length regulation, possibly by reducing rab-5 mediated endocytosis, and may also have a role in intraflagellar transport in cilia. Plays a role in the formation of muscle connections, also called mu [...] | E3 ubiquitin-protein ligase rpm-1; Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating lysine residues (By similarity). Shows esterification activity towards both threonine and serine, with a preference for threonine, and acts via two essential catalytic cysteine residues that relay ubiquitin to its substrate via thioester intermediates (By similarity). Mediates ubiquitination and subsequent proteasomal degradation of target proteins, including dlk-1. Negatively regulates a p38 MA [...] | 0.996 |
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