(11 nodes) Mostly uncharacterized, incl. Establishment of epithelial cell polarity, and Clc-like network (Caenorhabditis elegans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hyls-1	Hydrolethalus syndrome protein 1 homolog; Plays an important role ciliogenesis. Belongs to the HYLS1 family. (274 aa)
	C35E7.11	Uncharacterized protein. (129 aa)
	gasr-8	GAS (Human Growth Arrest-Specific) Related. (410 aa)
	set-5	SET domain-containing protein. (1558 aa)
	F10G2.1	UPF0376 protein F10G2.1. (201 aa)
	K10D6.2	Uncharacterized protein. (287 aa)
	K10G6.4	Uncharacterized protein. (459 aa)
	dyf-19	Uncharacterized protein. (534 aa)
	Y44A6D.2	Uncharacterized protein. (76 aa)
	Y55D5A.1	Uncharacterized protein. (285 aa)
	Y57G11C.32	Uncharacterized protein. (795 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C35E7.11	F10G2.1	C35E7.11.1	F10G2.1.1	Uncharacterized protein.	UPF0376 protein F10G2.1.	0.916
C35E7.11	K10D6.2	C35E7.11.1	K10D6.2b.1	Uncharacterized protein.	Uncharacterized protein.	0.820
C35E7.11	K10G6.4	C35E7.11.1	K10G6.4.1	Uncharacterized protein.	Uncharacterized protein.	0.891
C35E7.11	Y44A6D.2	C35E7.11.1	Y44A6D.2.1	Uncharacterized protein.	Uncharacterized protein.	0.807
C35E7.11	Y55D5A.1	C35E7.11.1	Y55D5A.1a.1	Uncharacterized protein.	Uncharacterized protein.	0.916
F10G2.1	C35E7.11	F10G2.1.1	C35E7.11.1	UPF0376 protein F10G2.1.	Uncharacterized protein.	0.916
F10G2.1	K10D6.2	F10G2.1.1	K10D6.2b.1	UPF0376 protein F10G2.1.	Uncharacterized protein.	0.810
F10G2.1	K10G6.4	F10G2.1.1	K10G6.4.1	UPF0376 protein F10G2.1.	Uncharacterized protein.	0.890
F10G2.1	Y44A6D.2	F10G2.1.1	Y44A6D.2.1	UPF0376 protein F10G2.1.	Uncharacterized protein.	0.808
F10G2.1	Y55D5A.1	F10G2.1.1	Y55D5A.1a.1	UPF0376 protein F10G2.1.	Uncharacterized protein.	0.914
K10D6.2	C35E7.11	K10D6.2b.1	C35E7.11.1	Uncharacterized protein.	Uncharacterized protein.	0.820
K10D6.2	F10G2.1	K10D6.2b.1	F10G2.1.1	Uncharacterized protein.	UPF0376 protein F10G2.1.	0.810
K10D6.2	K10G6.4	K10D6.2b.1	K10G6.4.1	Uncharacterized protein.	Uncharacterized protein.	0.712
K10D6.2	Y44A6D.2	K10D6.2b.1	Y44A6D.2.1	Uncharacterized protein.	Uncharacterized protein.	0.562
K10D6.2	Y55D5A.1	K10D6.2b.1	Y55D5A.1a.1	Uncharacterized protein.	Uncharacterized protein.	0.833
K10G6.4	C35E7.11	K10G6.4.1	C35E7.11.1	Uncharacterized protein.	Uncharacterized protein.	0.891
K10G6.4	F10G2.1	K10G6.4.1	F10G2.1.1	Uncharacterized protein.	UPF0376 protein F10G2.1.	0.890
K10G6.4	K10D6.2	K10G6.4.1	K10D6.2b.1	Uncharacterized protein.	Uncharacterized protein.	0.712
K10G6.4	Y44A6D.2	K10G6.4.1	Y44A6D.2.1	Uncharacterized protein.	Uncharacterized protein.	0.691
K10G6.4	Y55D5A.1	K10G6.4.1	Y55D5A.1a.1	Uncharacterized protein.	Uncharacterized protein.	0.892