Your Input: | |||||
xnd-1 | X chromosome NonDisjunction factor. (702 aa) | ||||
syp-2 | Uncharacterized protein. (213 aa) | ||||
dsb-1 | Double-Strand Break factor. (385 aa) | ||||
coh-3 | Rad21_Rec8 domain-containing protein. (607 aa) | ||||
msh-5 | MutS protein homolog 5; Crucial component in meiotic recombination, functioning at some point after the initiation step of recombination. Plays a role in promoting the crossover outcome of meiotic recombination events. Required for formation of normal meiotic crossover, and crossover and chiasmata generated by artificially made DNA breaks. (1369 aa) | ||||
dsb-2 | Double-Strand Break factor. (280 aa) | ||||
syp-3 | Uncharacterized protein. (224 aa) | ||||
htp-1 | HORMA domain-containing protein. (352 aa) | ||||
sun-1 | Sun domain-containing protein 1; Involved in centrosome attachment to the nucleus. Required for zyg-12 localization to the nuclear envelope. Together with pot-1, it is required to anchor telomeres to the nuclear envelope in embryos. (473 aa) | ||||
htp-3 | HORMA domain-containing protein. (739 aa) | ||||
syp-4 | Synaptonemal complex protein 4; Constitutes an element of the transverse filaments of the synaptonemal complex (SC), formed between homologous chromosomes during meiotic prophase I, and is required for the assembly of the central region of the SC. Required for chromosome synapsis and chiasma formation between homologous chromosomes during meiosis, mechanisms that are crucial for crossover formation and meiotic recombination. (605 aa) | ||||
zhp-3 | RING-type domain-containing protein. (389 aa) | ||||
rmh-1 | DUF1767 domain-containing protein. (926 aa) | ||||
spo-11 | Meiotic recombination protein spo-11; Required for meiotic recombination. Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. (425 aa) | ||||
zim-3 | Zinc finger In Meiosis. (581 aa) | ||||
him-8 | C2H2-type domain-containing protein. (361 aa) | ||||
zim-1 | C2H2-type domain-containing protein. (606 aa) | ||||
him-17 | High Incidence of Males (Increased X chromosome loss). (954 aa) | ||||
rec-8 | Meiotic recombination protein rec-8; Plays a role in meiotic chromosome cohesion and segregation. Necessary for sister chromatid co- orientation and sister chromatid cohension until meiosis II. May also be required for repair of programmed meiotic double stranded breaks. During spermatogenesis, likely involved in spermatocyte centriole cohesion, thus preventing their separation during the second meiotic division. Belongs to the rad21 family. Highly divergent. (781 aa) | ||||
coh-4 | Rad21_Rec8 domain-containing protein. (609 aa) | ||||
cosa-1 | CrossOver Site Associated. (360 aa) | ||||
htp-2 | HORMA domain-containing protein. (352 aa) | ||||
him-14 | MutS protein homolog him-14; Required during the pachytene stage of meiotic prophase for the formation of crossovers between homologous chromosomes. Not needed for pairing or synapsis. May promote crossing over by interfering with Holliday junction branch migration. Has no apparent role in DNA mismatch repair. (842 aa) | ||||
him-3 | HORMA domain-containing protein. (291 aa) | ||||
zyg-12 | Zygote defective protein 12; Cytoskeletal linker protein, which is essential for attachment of the centrosome to the nucleus. Required for dynein localization to the nuclear envelope. Forms a LINC (LInker of Nucleoskeleton and Cytoskeleton) complex together with unc-84, that may be involved in DNA damage repair ; Belongs to the hook family. (777 aa) |