(16 nodes) Small-subunit processome network (Caenorhabditis elegans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	B0280.9	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family. (429 aa)
	krr-1	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (370 aa)
	let-716	Uncharacterized protein. (1743 aa)
	F13H8.2	WD_REPEATS_REGION domain-containing protein. (929 aa)
	utp-20	DRIM domain-containing protein. (2613 aa)
	wdr-46	WD_REPEATS_REGION domain-containing protein. (580 aa)
	nath-10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1043 aa)
	F55F8.3	Periodic tryptophan protein 2 homolog; Belongs to the WD repeat PWP2 family. (910 aa)
	byn-1	Uncharacterized protein byn-1; Belongs to the bystin family. (449 aa)
	T20B12.3	Uncharacterized protein T20B12.3; Belongs to the CBF/MAK21 family. (504 aa)
	Y45F10D.7	Uncharacterized protein. (924 aa)
	nol-14	NucleOLar protein. (829 aa)
	Y53C12B.1	WD_REPEATS_REGION domain-containing protein. (793 aa)
	Y75B8A.7	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (648 aa)
	toe-1	HEAT repeat-containing protein 1 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity); Belongs to the HEATR1/UTP10 family. (1650 aa)
	ZK795.3	Brix domain-containing protein ZK795.3. (292 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0280.9	F13H8.2	B0280.9.1	F13H8.2.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	WD_REPEATS_REGION domain-containing protein.	0.999
B0280.9	F55F8.3	B0280.9.1	F55F8.3.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	Periodic tryptophan protein 2 homolog; Belongs to the WD repeat PWP2 family.	0.999
B0280.9	T20B12.3	B0280.9.1	T20B12.3.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	Uncharacterized protein T20B12.3; Belongs to the CBF/MAK21 family.	0.997
B0280.9	Y45F10D.7	B0280.9.1	Y45F10D.7.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	Uncharacterized protein.	0.999
B0280.9	Y53C12B.1	B0280.9.1	Y53C12B.1.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	WD_REPEATS_REGION domain-containing protein.	0.999
B0280.9	Y75B8A.7	B0280.9.1	Y75B8A.7.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family.	0.997
B0280.9	ZK795.3	B0280.9.1	ZK795.3.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	Brix domain-containing protein ZK795.3.	0.996
B0280.9	byn-1	B0280.9.1	F57B9.5.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	Uncharacterized protein byn-1; Belongs to the bystin family.	0.999
B0280.9	krr-1	B0280.9.1	C05C8.2.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.	0.999
B0280.9	let-716	B0280.9.1	C16A3.3.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	Uncharacterized protein.	0.986
B0280.9	nath-10	B0280.9.1	F55A12.8.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.995
B0280.9	nol-14	B0280.9.1	Y48G1A.4.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	NucleOLar protein.	0.998
B0280.9	toe-1	B0280.9.1	ZK430.1.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	HEAT repeat-containing protein 1 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity); Belongs to the HEATR1/UTP10 family.	0.998
B0280.9	utp-20	B0280.9.1	F18C5.3.1	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	DRIM domain-containing protein.	0.987
B0280.9	wdr-46	B0280.9.1	F28D1.1.2	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	WD_REPEATS_REGION domain-containing protein.	0.997
F13H8.2	B0280.9	F13H8.2.1	B0280.9.1	WD_REPEATS_REGION domain-containing protein.	U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family.	0.999
F13H8.2	F55F8.3	F13H8.2.1	F55F8.3.1	WD_REPEATS_REGION domain-containing protein.	Periodic tryptophan protein 2 homolog; Belongs to the WD repeat PWP2 family.	0.999
F13H8.2	T20B12.3	F13H8.2.1	T20B12.3.1	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein T20B12.3; Belongs to the CBF/MAK21 family.	0.999
F13H8.2	Y45F10D.7	F13H8.2.1	Y45F10D.7.1	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.999
F13H8.2	Y53C12B.1	F13H8.2.1	Y53C12B.1.1	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.999