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| | cyn-10 | Peptidyl-prolyl cis-trans isomerase 10; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (161 aa) |
| | B0361.2 | CWF19-like protein 2 homolog; Belongs to the CWF19 family. (460 aa) |
| | moa-2 | Protein moa-2. (87 aa) |
| | B0495.8 | Uncharacterized protein B0495.8; Belongs to the Luc7 family. (313 aa) |
| | mog-4 | Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-4; ATP-binding RNA helicase involved in pre-mRNA splicing (Probable). Operates during embryogenesis. (1008 aa) |
| | bud-31 | Protein BUD31 homolog; Involved in pre-mRNA splicing process. (147 aa) |
| | sap-49 | Splicing factor 3B subunit 4; Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (By similarity). (388 aa) |
| | snrp-40.2 | WD_REPEATS_REGION domain-containing protein. (331 aa) |
| | rbmx-2 | RRM domain-containing protein. (302 aa) |
| | C32E8.5 | FHA domain-containing protein. (299 aa) |
| | cyn-12 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (169 aa) |
| | prp-4 | WD_REPEATS_REGION domain-containing protein. (496 aa) |
| | C39E9.11 | Proline Rich mitotic Checkpoint Control factor homolog. (405 aa) |
| | C47E8.4 | Protein FAM50 homolog; Belongs to the FAM50 family. (326 aa) |
| | prp-8 | Pre-mRNA-splicing factor 8 homolog; Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site. (2329 aa) |
| | C50D2.5 | Splicing factor 3B subunit 6-like protein; Necessary for the splicing of pre-mRNA. (138 aa) |
| | C50D2.8 | Uncharacterized protein. (319 aa) |
| | syf-1 | SYF pre-mRNA splicing factor homolog. (855 aa) |
| | snr-4 | Probable small nuclear ribonucleoprotein Sm D2; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity). (118 aa) |
| | prp-38 | Yeast PRP (Splicing factor) related. (320 aa) |
| | plrg-1 | WD_REPEATS_REGION domain-containing protein. (494 aa) |
| | cdc-5L | Cell Division Cycle related. (755 aa) |
| | let-504 | Nkap_C domain-containing protein. (504 aa) |
| | mog-5 | Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5; Could act late in the splicing of pre-mRNA and mediate the release of the spliced mRNA from spliceosomes; Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily. (1200 aa) |
| | ddx-23 | DEAD boX helicase homolog; Belongs to the DEAD box helicase family. (730 aa) |
| | F08B4.7 | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (142 aa) |
| | snrp-40.1 | WD_REPEATS_REGION domain-containing protein. (331 aa) |
| | usp-39 | Ubiquitin Specific Protease. (602 aa) |
| | repo-1 | Matrin-type domain-containing protein. (222 aa) |
| | F14F9.5 | Uncharacterized protein F14F9.5. (314 aa) |
| | F19F10.9 | Uncharacterized protein. (829 aa) |
| | prpf-4 | Protein kinase domain-containing protein. (775 aa) |
| | F25B4.5 | Uncharacterized protein. (710 aa) |
| | rsr-1 | PWI domain-containing protein. (601 aa) |
| | lsm-5 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA; Belongs to the snRNP Sm proteins family. (91 aa) |
| | lsm-4 | Probable U6 snRNA-associated Sm-like protein LSm4; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (123 aa) |
| | F32B6.3 | SFM domain-containing protein. (352 aa) |
| | let-858 | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay (By similarity). Required for early embryogenesis and tissue differentiation; Belongs to the CWC22 family. (897 aa) |
| | F33H1.3 | Uncharacterized protein F33H1.3. (359 aa) |
| | F37A4.2 | Uncharacterized protein F37A4.2. (189 aa) |
| | F37C12.1 | Uncharacterized protein. (323 aa) |
| | sig-7 | Peptidyl-prolyl cis-trans isomerase sig-7; Probable PPIase that accelerates the folding of proteins (By similarity). It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Involved in RNA polymerase II (RNA pol II)-mediated transcription elongation, and in primary transcript splicing, including co-transcriptional trans- splicing, in association with the catalytic subunit of the RNA pol II complex ama-1. Also plays a role in the regulation of elongation-dependent phosphorylation of ama-1 to control transcription. Involved in the transc [...] (427 aa) |
| | mfap-1 | Microfibrillar-associated protein 1; Involved in pre-mRNA splicing. (466 aa) |
| | prp-17 | WD_REPEATS_REGION domain-containing protein. (567 aa) |
| | mog-3 | Sex determining protein MOG-3. (451 aa) |
| | isy-1 | Protein isy-1; Regulates the processing of the mir-60 microRNA (miRNA), which in turn negatively regulates the expression of the transcription factor zip-10. Does not affect the splicing of zip-10 ; Belongs to the ISY1 family. (267 aa) |
| | F53F4.14 | Sde2_N_Ubi domain-containing protein. (500 aa) |
| | F53H1.1 | Uncharacterized protein. (970 aa) |
| | F54E4.4 | Uncharacterized protein. (487 aa) |
| | ddx-17 | DEAD boX helicase homolog; Belongs to the DEAD box helicase family. (561 aa) |
| | rde-12 | DEAD-box ATP-dependent RNA helicase rde-12; Probable ATP-dependent RNA helicase involved in RNAi-mediated gene silencing. Specifically required in the endogenous siRNA pathway for biogenesis of secondary endogenous small interfering RNA (siRNA) intermediates called 22G-RNAs. May associate with and recruit rde- 10 to primary siRNA-targeted mRNA for secondary siRNA synthesis. May be recruited to target mRNAs by rde-1 and/or ergo-1. (959 aa) |
| | cyn-4 | Peptidyl-prolyl cis-trans isomerase 4; May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins. Influences the hermaphrodite switch from spermatogenesis to oogenesis. Required for body wall muscle cell development. (523 aa) |
| | mog-2 | Probable U2 small nuclear ribonucleoprotein A; This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA. Required maternally for early embryonic development and zygotically for germline and somatic development. Has a role in the switch from mitosis to meiosis. Might function in alternative splicing. (253 aa) |
| | rnf-113 | Probable E3 ubiquitin-protein ligase rnf113; May function as E3 ubiquitin-protein ligase that catalyzes the transfer of ubiquitin onto target proteins. May play a role in DNA repair via its role in the synthesis of 'Lys-63'-linked polyubiquitin chains that recruit proteins involved in repair to sites of DNA damage by alkylating agents. (384 aa) |
| | K01G5.8 | Uncharacterized protein. (107 aa) |
| | teg-4 | CPSF_A domain-containing protein. (1220 aa) |
| | mog-1 | Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-1; Probable ATP-binding RNA helicase involved in pre-mRNA splicing; Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily. (1131 aa) |
| | rnp-7 | RRM domain-containing protein. (332 aa) |
| | syf-2 | Pre-mRNA-splicing factor syf-2; May be involved in pre-mRNA splicing. (234 aa) |
| | K07C5.6 | Pre-mRNA-splicing factor SLU7; Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Belongs to the SLU7 family. (647 aa) |
| | rnp-3 | RNP (RRM RNA binding domain) containing. (217 aa) |
| | rnp-2 | RNP (RRM RNA binding domain) containing. (206 aa) |
| | M01E11.2 | DUF1716 domain-containing protein. (544 aa) |
| | prp-3 | Yeast PRP (Splicing factor) related. (621 aa) |
| | M03F8.3 | Uncharacterized protein. (747 aa) |
| | M88.4 | PID domain-containing protein. (365 aa) |
| | R07E5.1 | G patch domain-containing protein 1 homolog. (812 aa) |
| | R08D7.1 | BUD13 homolog; Belongs to the CWC26 family. (458 aa) |
| | gkow-1 | G-patch domain and KOW motifs-containing protein homolog 1; Belongs to the MOS2 family. (462 aa) |
| | sel-13 | Suppressor/Enhancer of Lin-12. (234 aa) |
| | gad-1 | Gastrulation defective protein 1; Required for initiation of gastrulation. (620 aa) |
| | sftb-1 | SF3b1 domain-containing protein. (1322 aa) |
| | cwc-15 | Spliceosome-associated protein CWC15 homolog; Component of a spliceosomal complex that is required for activating pre-mRNA splicing. (230 aa) |
| | prp-19 | Pre-mRNA-processing factor 19; Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Core component of the NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity (By similarity). Together with emb-4, necessary for interaction of rnp-4, a probable exon junction complex component, with mRNAs and spliceosomal snRNAs. Plays a role in nuclear retention of unspliced mRNAs. Belongs to the WD repeat PRP19 family. (492 aa) |
| | gut-2 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (97 aa) |
| | rbm-22 | RNA Binding Motif protein homolog. (408 aa) |
| | T12A2.6 | Uncharacterized protein. (689 aa) |
| | bcas-2 | BCAS splicing factor homolog. (238 aa) |
| | T13H5.4 | Matrin-type domain-containing protein. (500 aa) |
| | pqbp-1.1 | WW domain-containing protein. (280 aa) |
| | skp-1 | Uncharacterized protein T27F2.1. (535 aa) |
| | snr-3 | Probable small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures (By similarity). Belongs to the snRNP core protein family. (126 aa) |
| | sftb-2 | PSP domain-containing protein. (602 aa) |
| | cacn-1 | Cactin; Plays a role during early embryonic development. Required for the distal tip cell migration at the end of larval development and for gonad morphogenesis. (657 aa) |
| | rbm-25 | PWI domain-containing protein. (707 aa) |
| | prp-21 | Yeast PRP (Splicing factor) related. (655 aa) |
| | snr-2 | Probable small nuclear ribonucleoprotein-associated protein B; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure (By similarity); Belongs to the snRNP SmB/SmN family. (160 aa) |
| | prp-31 | Nop domain-containing protein. (504 aa) |
| | sfa-1 | CCHC-type domain-containing protein. (699 aa) |
| | cyn-13 | Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. (331 aa) |
| | snr-1 | Small nuclear ribonucleoprotein Sm D3; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity); Belongs to the snRNP core protein family. (136 aa) |
| | orc-3 | ORC (Origin Recognition Complex) subunit. (612 aa) |
| | cyn-16 | PPIase cyclophilin-type domain-containing protein. (483 aa) |
| | Y18H1A.2 | Cir_N domain-containing protein. (286 aa) |
| | Y40B1A.2 | WW domain-containing protein. (120 aa) |
| | snrp-200 | Putative U5 small nuclear ribonucleoprotein 200 kDa helicase; Putative RNA helicase involved in the second step of RNA splicing; Belongs to the helicase family. SKI2 subfamily. (2145 aa) |
| | snr-6 | Probable small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (90 aa) |
| | dxbp-1 | Kin17_mid domain-containing protein. (404 aa) |
| | Y54E2A.8 | Uncharacterized protein. (485 aa) |
| | phf-5 | PHd Finger family. (110 aa) |
| | Y54G2A.12 | WD_REPEATS_REGION domain-containing protein. (274 aa) |
| | Y54G2A.75 | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa) |
| | rsr-2 | Cwf21 domain-containing protein. (425 aa) |
| | prp-6 | Yeast PRP (Splicing factor) related. (968 aa) |
| | lsm-3 | U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa) |
| | cus-2 | Uncharacterized protein. (442 aa) |
| | ddx-35 | Probable ATP-dependent RNA helicase DHX35 homolog. (732 aa) |
| | Y69A2AR.21 | Uncharacterized protein. (169 aa) |
| | vamp-7 | V-SNARE coiled-coil homology domain-containing protein. (261 aa) |
| | Y71F9AL.12 | Uncharacterized protein. (289 aa) |
| | snr-7 | Probable small nuclear ribonucleoprotein G; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (77 aa) |
| | lsm-6 | Sm domain-containing protein; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (77 aa) |
| | lsm-8 | U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa) |
| | emb-4 | Uncharacterized protein. (1467 aa) |
| | Y82E9BR.2 | Uncharacterized protein. (530 aa) |
| | cyn-15 | PPIase cyclophilin-type domain-containing protein. (629 aa) |
| | ZK1098.1 | WW domain-containing protein ZK1098.1. (724 aa) |
| | ZK1127.6 | Uncharacterized protein. (424 aa) |
| | cyp-44A1 | Probable cytochrome P450 CYP44; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (489 aa) |
| | eftu-2 | Tr-type G domain-containing protein. (974 aa) |
| | lsm-7 | Sm domain-containing protein. (104 aa) |
| | snr-5 | Probable small nuclear ribonucleoprotein F; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. (85 aa) |
| | snu-23 | Putative zinc finger matrin-type protein snu-23. (217 aa) |
| | rnp-1 | RNA-binding protein rnp-1; RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development. (305 aa) |
