STRINGSTRING
cyn-12 cyn-12 C47E8.4 C47E8.4 let-504 let-504 mog-5 mog-5 rsr-1 rsr-1 F37A4.2 F37A4.2 sig-7 sig-7 prp-17 prp-17 F53F4.14 F53F4.14 ddx-17 ddx-17 cyn-4 cyn-4 K01G5.8 K01G5.8 R07E5.1 R07E5.1 gad-1 gad-1 cacn-1 cacn-1 Y18H1A.2 Y18H1A.2 ddx-35 ddx-35 Y69A2AR.21 Y69A2AR.21 cyn-15 cyn-15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cyn-12Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (169 aa)
C47E8.4Protein FAM50 homolog; Belongs to the FAM50 family. (326 aa)
let-504Nkap_C domain-containing protein. (504 aa)
mog-5Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5; Could act late in the splicing of pre-mRNA and mediate the release of the spliced mRNA from spliceosomes; Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily. (1200 aa)
rsr-1PWI domain-containing protein. (601 aa)
F37A4.2Uncharacterized protein F37A4.2. (189 aa)
sig-7Peptidyl-prolyl cis-trans isomerase sig-7; Probable PPIase that accelerates the folding of proteins (By similarity). It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Involved in RNA polymerase II (RNA pol II)-mediated transcription elongation, and in primary transcript splicing, including co-transcriptional trans- splicing, in association with the catalytic subunit of the RNA pol II complex ama-1. Also plays a role in the regulation of elongation-dependent phosphorylation of ama-1 to control transcription. Involved in the transc [...] (427 aa)
prp-17WD_REPEATS_REGION domain-containing protein. (567 aa)
F53F4.14Sde2_N_Ubi domain-containing protein. (500 aa)
ddx-17DEAD boX helicase homolog; Belongs to the DEAD box helicase family. (561 aa)
cyn-4Peptidyl-prolyl cis-trans isomerase 4; May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins. Influences the hermaphrodite switch from spermatogenesis to oogenesis. Required for body wall muscle cell development. (523 aa)
K01G5.8Uncharacterized protein. (107 aa)
R07E5.1G patch domain-containing protein 1 homolog. (812 aa)
gad-1Gastrulation defective protein 1; Required for initiation of gastrulation. (620 aa)
cacn-1Cactin; Plays a role during early embryonic development. Required for the distal tip cell migration at the end of larval development and for gonad morphogenesis. (657 aa)
Y18H1A.2Cir_N domain-containing protein. (286 aa)
ddx-35Probable ATP-dependent RNA helicase DHX35 homolog. (732 aa)
Y69A2AR.21Uncharacterized protein. (169 aa)
cyn-15PPIase cyclophilin-type domain-containing protein. (629 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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