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| | gspd-1 | Glucose-6-phosphate 1-dehydrogenase; Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes. (522 aa) |
| | spl-2 | Sphingosine Phosphate Lyase. (542 aa) |
| | rpia-1 | Probable-ribose 5-phosphate isomerase; Belongs to the ribose 5-phosphate isomerase family. (251 aa) |
| | B0303.14 | Uncharacterized protein B0303.14. (407 aa) |
| | acly-2 | ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1099 aa) |
| | prdh-1 | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate (By similarity). Through proline catabolism, promotes reactive oxygen species (ROS) production and the transcription of skn-1 target genes in response to bacterial infection by P.aeruginosa. (616 aa) |
| | sdha-1 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (646 aa) |
| | pdhb-1 | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (352 aa) |
| | icl-1 | Bifunctional glyoxylate cycle protein; In the C-terminal section; belongs to the malate synthase family. (968 aa) |
| | sucl-1 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (322 aa) |
| | glna-1 | ANK_REP_REGION domain-containing protein. (856 aa) |
| | C13B9.2 | Uncharacterized protein C13B9.2; Belongs to the glycerate kinase type-2 family. (458 aa) |
| | got-2.2 | Aspartate aminotransferase. (414 aa) |
| | oatr-1 | Probable ornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa) |
| | idhg-2 | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (373 aa) |
| | dlat-2 | 2-oxoacid_dh domain-containing protein. (337 aa) |
| | C32F10.8 | Aminotran_1_2 domain-containing protein. (504 aa) |
| | sdha-2 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (640 aa) |
| | idh-2 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (435 aa) |
| | idhb-1 | Probable isocitrate dehydrogenase [NAD] subunit beta, mitochondrial; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (379 aa) |
| | acer-1 | AcetylCoA_hyd_C domain-containing protein. (471 aa) |
| | got-2.1 | Aspartate aminotransferase. (419 aa) |
| | gln-1 | Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (385 aa) |
| | ddo-1 | D-aspartate oxidase 1; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Highest catalytic efficiency for D-Glu followed by D-Asp and NMDA. May play a role in the egg-laying events and early development of the worm, in addition to quality control of the germ cells. Belongs to the DAMOX/DASOX family. (334 aa) |
| | C50D2.7 | Probable ADP-dependent glucokinase; Catalyzes the phosphorylation of D-glucose to D-glucose 6- phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency (By similarity); Belongs to the ADP-dependent glucokinase family. (502 aa) |
| | pfk-1.2 | ATP-dependent 6-phosphofructokinase 2; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (756 aa) |
| | sucg-1 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (415 aa) |
| | alh-10 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (506 aa) |
| | acly-1 | Probable ATP-citrate synthase; ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1106 aa) |
| | pyc-1 | Pyruvate carboxylase 1; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1175 aa) |
| | gbh-1 | Probable gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine. (421 aa) |
| | glna-2 | Putative glutaminase 2. (605 aa) |
| | aldo-2 | Fructose-bisphosphate aldolase 2. (366 aa) |
| | alh-9 | Putative aldehyde dehydrogenase family 7 member A1 homolog; Belongs to the aldehyde dehydrogenase family. (531 aa) |
| | tkt-1 | Transket_pyr domain-containing protein. (618 aa) |
| | F07A11.5 | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (314 aa) |
| | F08F8.7 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa) |
| | ldh-1 | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. LDH family. (336 aa) |
| | hxk-1 | Phosphotransferase; Belongs to the hexokinase family. (500 aa) |
| | ddo-2 | D-aspartate oxidase 2; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Highest catalytic efficiency for D-Glu followed by D-Asp and NMDA. May play a role in the egg-laying events and early development of the worm, in addition to quality control of the germ cells. (334 aa) |
| | mdh-2 | Probable malate dehydrogenase, mitochondrial. (341 aa) |
| | ddo-3 | D-aspartate oxidase 3; Selectively catalyzes the oxidative deamination of D- aspartate and its N-methylated derivative, N-methyl D-aspartate. Has no activity towards L-amino acids or N-methyl-L-aspartic acid. May play a role in the egg-laying events and maturation processes of the reproductive organs. (383 aa) |
| | dlat-1 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (507 aa) |
| | sucl-2 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (321 aa) |
| | pyk-1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (913 aa) |
| | F26D11.1 | Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (174 aa) |
| | glna-3 | Putative glutaminase 3. (583 aa) |
| | sdhd-1 | Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (145 aa) |
| | gpd-4 | Glyceraldehyde-3-phosphate dehydrogenase 4. (341 aa) |
| | idhg-1 | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (396 aa) |
| | F42A8.1 | Uncharacterized protein F42A8.1. (370 aa) |
| | sdhb-1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (298 aa) |
| | alh-11 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (687 aa) |
| | idha-1 | Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (358 aa) |
| | alh-7 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (493 aa) |
| | mdh-1 | Malate dehydrogenase. (336 aa) |
| | suca-1 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (435 aa) |
| | F48E8.3 | FAD_binding_2 domain-containing protein. (493 aa) |
| | F54D5.7 | Probable glutaryl-CoA dehydrogenase, mitochondrial. (409 aa) |
| | alh-1 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (510 aa) |
| | aco-2 | Probable aconitate hydratase, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (777 aa) |
| | F55G1.9 | Putative pyrroline-5-carboxylate reductase. (299 aa) |
| | alh-6 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (563 aa) |
| | idh-1 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (435 aa) |
| | fum-1 | Probable fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. In mitochondrion, catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (501 aa) |
| | hxk-2 | Phosphotransferase. (552 aa) |
| | gta-1 | Probable 4-aminobutyrate aminotransferase, mitochondrial. (483 aa) |
| | alh-2 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (514 aa) |
| | fbp-1 | FBPase domain-containing protein; Belongs to the FBPase class 1 family. (341 aa) |
| | gpd-3 | Glyceraldehyde-3-phosphate dehydrogenase 3. (341 aa) |
| | gpd-2 | Glyceraldehyde-3-phosphate dehydrogenase 2. (341 aa) |
| | fah-1 | Fumarylacetoacetase. (418 aa) |
| | dld-1 | Dihydrolipoyl dehydrogenase, mitochondrial. (495 aa) |
| | gbh-2 | Gamma Butyrobetaine Hydroxylase. (409 aa) |
| | M153.1 | Uncharacterized protein. (293 aa) |
| | aass-1 | AminoAdipate-Semialdehyde Synthase homolog. (952 aa) |
| | R05F9.6 | Uncharacterized protein; Belongs to the phosphohexose mutase family. (568 aa) |
| | pck-2 | Phosphoenolypyruvate CarboxyKinase. (654 aa) |
| | R151.2 | Pribosyltran_N domain-containing protein. (446 aa) |
| | got-1.2 | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the central nervous system. (408 aa) |
| | pgk-1 | Probable phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa) |
| | aldo-1 | Fructose-bisphosphate aldolase 1. (365 aa) |
| | pdha-1 | Probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (414 aa) |
| | alh-4 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (494 aa) |
| | mev-1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). Mediates resistance to enteropathogenic E.coli infection. Belongs to the cytochrome b560 family. (182 aa) |
| | gpd-1 | Glyceraldehyde-3-phosphate dehydrogenase 1. (341 aa) |
| | cts-1 | Probable citrate synthase, mitochondrial. (468 aa) |
| | enol-1 | Enolase; Belongs to the enolase family. (465 aa) |
| | T21F4.1 | Uncharacterized protein; Belongs to the arginase family. (327 aa) |
| | ogdh-1 | 2-oxoglutarate dehydrogenase, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (1029 aa) |
| | alh-13 | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (802 aa) |
| | T25B9.9 | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa) |
| | dlst-1 | Lipoyl-binding domain-containing protein. (463 aa) |
| | pck-1 | PEPCK_GTP domain-containing protein. (651 aa) |
| | W07E11.1 | Glutamine amidotransferase type-2 domain-containing protein. (2185 aa) |
| | gln-3 | Glutamine synthetase. (388 aa) |
| | tpi-1 | Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. (247 aa) |
| | tald-1 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (319 aa) |
| | Y43F4B.5 | Uncharacterized protein; Belongs to the phosphohexose mutase family. (595 aa) |
| | Y45G12B.3 | L-2-hydroxyglutarate dehydrogenase, mitochondrial. (433 aa) |
| | men-1 | Malic enzyme. (620 aa) |
| | Y57G11C.3 | Putative 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily. (269 aa) |
| | spl-1 | Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Essential for normal development, intestinal integrity, growth and reproduction. (552 aa) |
| | alh-12 | Aldedh domain-containing protein. (499 aa) |
| | pfk-1.1 | ATP-dependent 6-phosphofructokinase 1; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (814 aa) |
| | gpi-1 | Glucose-6-phosphate isomerase; Belongs to the GPI family. (586 aa) |
| | nit-1 | CN hydrolase domain-containing protein. (305 aa) |
| | ZK1320.9 | AcetylCoA_hyd_C domain-containing protein. (472 aa) |
| | aco-1 | Probable cytoplasmic aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (887 aa) |
| | pyk-2 | Pyruvate kinase; Belongs to the pyruvate kinase family. (515 aa) |
| | fahd-1 | Fumarylacetoacetate hydrolase domain-containing protein 1; May have hydrolase activity. (214 aa) |
| | hdl-1 | Probable aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine; Belongs to the group II decarboxylase family. (905 aa) |
| | gdh-1 | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (536 aa) |
| | ogdh-2 | Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 homolog, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). (911 aa) |
