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spl-2 spl-2 prdh-1 prdh-1 glna-1 glna-1 C13B9.2 C13B9.2 oatr-1 oatr-1 gln-1 gln-1 alh-10 alh-10 gbh-1 gbh-1 glna-2 glna-2 alh-9 alh-9 glna-3 glna-3 alh-11 alh-11 alh-7 alh-7 alh-1 alh-1 F55G1.9 F55G1.9 alh-6 alh-6 gta-1 gta-1 alh-2 alh-2 gbh-2 gbh-2 M153.1 M153.1 aass-1 aass-1 alh-4 alh-4 T21F4.1 T21F4.1 alh-13 alh-13 W07E11.1 W07E11.1 gln-3 gln-3 Y45G12B.3 Y45G12B.3 spl-1 spl-1 alh-12 alh-12 nit-1 nit-1 hdl-1 hdl-1 gdh-1 gdh-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
spl-2Sphingosine Phosphate Lyase. (542 aa)
prdh-1Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate (By similarity). Through proline catabolism, promotes reactive oxygen species (ROS) production and the transcription of skn-1 target genes in response to bacterial infection by P.aeruginosa. (616 aa)
glna-1ANK_REP_REGION domain-containing protein. (856 aa)
C13B9.2Uncharacterized protein C13B9.2; Belongs to the glycerate kinase type-2 family. (458 aa)
oatr-1Probable ornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
gln-1Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (385 aa)
alh-10Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (506 aa)
gbh-1Probable gamma-butyrobetaine dioxygenase; Catalyzes the formation of L-carnitine from gamma- butyrobetaine. (421 aa)
glna-2Putative glutaminase 2. (605 aa)
alh-9Putative aldehyde dehydrogenase family 7 member A1 homolog; Belongs to the aldehyde dehydrogenase family. (531 aa)
glna-3Putative glutaminase 3. (583 aa)
alh-11Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (687 aa)
alh-7Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
alh-1Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (510 aa)
F55G1.9Putative pyrroline-5-carboxylate reductase. (299 aa)
alh-6Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (563 aa)
gta-1Probable 4-aminobutyrate aminotransferase, mitochondrial. (483 aa)
alh-2Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (514 aa)
gbh-2Gamma Butyrobetaine Hydroxylase. (409 aa)
M153.1Uncharacterized protein. (293 aa)
aass-1AminoAdipate-Semialdehyde Synthase homolog. (952 aa)
alh-4Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (494 aa)
T21F4.1Uncharacterized protein; Belongs to the arginase family. (327 aa)
alh-13Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (802 aa)
W07E11.1Glutamine amidotransferase type-2 domain-containing protein. (2185 aa)
gln-3Glutamine synthetase. (388 aa)
Y45G12B.3L-2-hydroxyglutarate dehydrogenase, mitochondrial. (433 aa)
spl-1Sphingosine-1-phosphate lyase; Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Essential for normal development, intestinal integrity, growth and reproduction. (552 aa)
alh-12Aldedh domain-containing protein. (499 aa)
nit-1CN hydrolase domain-containing protein. (305 aa)
hdl-1Probable aromatic-L-amino-acid decarboxylase; Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine; Belongs to the group II decarboxylase family. (905 aa)
gdh-1Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (536 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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