STRINGSTRING
his-45 his-45 his-47 his-47 his-48 his-48 his-35 his-35 nap-1 nap-1 his-51 his-51 his-54 his-54 his-53 his-53 his-52 his-52 his-49 his-49 his-44 his-44 his-43 his-43 his-42 his-42 his-32 his-32 his-31 his-31 his-33 his-33 his-34 his-34 his-64 his-64 his-63 his-63 his-30 his-30 his-71 his-71 his-6 his-6 his-7 his-7 his-55 his-55 his-61 his-61 his-59 his-59 his-62 his-62 his-65 his-65 his-40 his-40 his-19 his-19 his-22 his-22 his-27 his-27 his-21 his-21 his-20 his-20 his-17 his-17 his-4 his-4 his-2 his-2 his-68 his-68 his-26 his-26 his-16 his-16 his-9 his-9 his-10 his-10 his-12 his-12 his-13 his-13 his-14 his-14 his-15 his-15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
his-45Histone H3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
his-47Histone H2A; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (127 aa)
his-48Probable histone H2B 4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa)
his-35Histone H2A; Belongs to the histone H2A family. (127 aa)
nap-1Nucleosome Assembly Protein; Belongs to the nucleosome assembly protein (NAP) family. (316 aa)
his-51Histone H2A. (127 aa)
his-54Histone H2B 2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (123 aa)
his-53Histone H2A. (127 aa)
his-52Histone H2B 2. (123 aa)
his-49Histone H3. (136 aa)
his-44Histone H2B 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (122 aa)
his-43Histone H2A. (127 aa)
his-42Histone H3. (136 aa)
his-32Histone H3. (136 aa)
his-31Histone H4. (103 aa)
his-33Histone H2A. (127 aa)
his-34Histone H2B 1. (122 aa)
his-64Histone H4. (103 aa)
his-63Histone H3. (136 aa)
his-30Histone H2A. (127 aa)
his-71Histone H3.3 type 1; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central [...] (136 aa)
his-6Histone H3. (136 aa)
his-7Histone H2A. (127 aa)
his-55Histone H3. (136 aa)
his-61Histone H2A. (127 aa)
his-59Histone H3. (136 aa)
his-62Probable histone H2B 4. (123 aa)
his-65Histone H2A. (127 aa)
his-40Histone H3. (136 aa)
his-19Histone H2A. (127 aa)
his-22Histone H2B 2. (123 aa)
his-27Histone H3. (136 aa)
his-21Histone H2A. (127 aa)
his-20Histone H2B 2. (123 aa)
his-17Histone H3. (136 aa)
his-4Histone H2B 2. (123 aa)
his-2Histone H3. (136 aa)
his-68Histone H2A. (127 aa)
his-26Histone H4. (103 aa)
his-16Histone H2A. (127 aa)
his-9Histone H3. (136 aa)
his-10Histone H4. (103 aa)
his-12Histone H2A. (127 aa)
his-13Histone H3. (136 aa)
his-14Histone H4. (103 aa)
his-15Histone H2B 1. (122 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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