30 items (Caenorhabditis elegans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mboa-4	Membrane Bound O-Acyl transferase, MBOAT; Belongs to the membrane-bound acyltransferase family. (511 aa)
	cdgs-1	Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns); Belongs to the CDS family. (465 aa)
	mboa-3	Membrane Bound O-Acyl transferase, MBOAT; Belongs to the membrane-bound acyltransferase family. (480 aa)
	acl-6	Probable glycerol-3-phosphate acyltransferase, mitochondrial; Belongs to the GPAT/DAPAT family. (718 aa)
	plpp-1.3	AcidPPc domain-containing protein. (304 aa)
	crls-1	Probable cardiolipin synthase (CMP-forming); Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (246 aa)
	acl-11	PlsC domain-containing protein. (368 aa)
	plc-1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. plc-1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity (By similarity). By activating IP3 receptor itr-1-mediated intracellular Ca(2+) release via the production of IP3, regulates ovulation by controlling contraction and/or dilation of the di [...] (1898 aa)
	dgk-4	Diacylglycerol kinase. (1339 aa)
	dgk-2	Diacylglycerol kinase. (536 aa)
	gpdh-1	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (374 aa)
	acl-4	PlsC domain-containing protein. (617 aa)
	F52C9.3	Uncharacterized protein F52C9.3. (439 aa)
	plpp-1.1	AcidPPc domain-containing protein. (385 aa)
	dgk-3	Probable diacylglycerol kinase 3; Involved in AFD-neuron mediated thermotaxis. Regulates behavior to environmental temperature. Thought to have a role in olfactory adaptation by affecting diacylglycerol levels. Belongs to the eukaryotic diacylglycerol kinase family. (795 aa)
	bus-18	PlsC domain-containing protein. (391 aa)
	acl-1	Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. (262 aa)
	mboa-2	O-acyltransferase. (498 aa)
	lpin-1	LNS2 domain-containing protein. (794 aa)
	dgk-5	Putative diacylglycerol kinase K06A1.6. (1150 aa)
	K07B1.4	Uncharacterized protein. (349 aa)
	gpdh-2	Probable glycerol-3-phosphate dehydrogenase 2. (392 aa)
	acl-5	PlsC domain-containing protein. (512 aa)
	acl-2	Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-2; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. (282 aa)
	plpp-1.2	Phospholipid phosphatase homolog 1.2 homolog. (358 aa)
	pisy-1	CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (220 aa)
	pgs-1	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin; Belongs to the CDP-alcohol phosphatidyltransferase class-II family. (446 aa)
	cept-2	Choline/EthanolaminePhosphoTransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (424 aa)
	acl-9	PlsC domain-containing protein. (399 aa)
	acl-3	Tafazzin family protein; Belongs to the taffazin family. (284 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F52C9.3	K07B1.4	F52C9.3.1	K07B1.4a.1	Uncharacterized protein F52C9.3.	Uncharacterized protein.	0.900
F52C9.3	acl-1	F52C9.3.1	F59F4.4.1	Uncharacterized protein F52C9.3.	Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-1; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.	0.905
F52C9.3	acl-11	F52C9.3.1	F28B3.9.2	Uncharacterized protein F52C9.3.	PlsC domain-containing protein.	0.901
F52C9.3	acl-2	F52C9.3.1	T06E8.1a.1	Uncharacterized protein F52C9.3.	Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-2; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.	0.905
F52C9.3	acl-4	F52C9.3.1	F49H12.6a.1	Uncharacterized protein F52C9.3.	PlsC domain-containing protein.	0.908
F52C9.3	acl-5	F52C9.3.1	R07E3.5a.2	Uncharacterized protein F52C9.3.	PlsC domain-containing protein.	0.908
F52C9.3	acl-6	F52C9.3.1	F08F3.2a.1	Uncharacterized protein F52C9.3.	Probable glycerol-3-phosphate acyltransferase, mitochondrial; Belongs to the GPAT/DAPAT family.	0.908
F52C9.3	acl-9	F52C9.3.1	ZK40.1.2	Uncharacterized protein F52C9.3.	PlsC domain-containing protein.	0.902
F52C9.3	bus-18	F52C9.3.1	F55A11.5.1	Uncharacterized protein F52C9.3.	PlsC domain-containing protein.	0.902
F52C9.3	mboa-3	F52C9.3.1	C54G7.2.2	Uncharacterized protein F52C9.3.	Membrane Bound O-Acyl transferase, MBOAT; Belongs to the membrane-bound acyltransferase family.	0.900
F52C9.3	mboa-4	F52C9.3.1	C08F8.4b.1	Uncharacterized protein F52C9.3.	Membrane Bound O-Acyl transferase, MBOAT; Belongs to the membrane-bound acyltransferase family.	0.900
K07B1.4	F52C9.3	K07B1.4a.1	F52C9.3.1	Uncharacterized protein.	Uncharacterized protein F52C9.3.	0.900
K07B1.4	dgk-2	K07B1.4a.1	F46H6.2a.1	Uncharacterized protein.	Diacylglycerol kinase.	0.901
K07B1.4	dgk-3	K07B1.4a.1	F54G8.2.1	Uncharacterized protein.	Probable diacylglycerol kinase 3; Involved in AFD-neuron mediated thermotaxis. Regulates behavior to environmental temperature. Thought to have a role in olfactory adaptation by affecting diacylglycerol levels. Belongs to the eukaryotic diacylglycerol kinase family.	0.902
K07B1.4	dgk-4	K07B1.4a.1	F42A9.1a.1	Uncharacterized protein.	Diacylglycerol kinase.	0.903
K07B1.4	dgk-5	K07B1.4a.1	K06A1.6e.1	Uncharacterized protein.	Putative diacylglycerol kinase K06A1.6.	0.902
K07B1.4	lpin-1	K07B1.4a.1	H37A05.1.1	Uncharacterized protein.	LNS2 domain-containing protein.	0.946
K07B1.4	mboa-2	K07B1.4a.1	H19N07.4a.2	Uncharacterized protein.	O-acyltransferase.	0.988
K07B1.4	plpp-1.1	K07B1.4a.1	F53C3.13b.1	Uncharacterized protein.	AcidPPc domain-containing protein.	0.942
K07B1.4	plpp-1.2	K07B1.4a.1	T28D9.3d.1	Uncharacterized protein.	Phospholipid phosphatase homolog 1.2 homolog.	0.947