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glt-5 glt-5 glt-7 glt-7 glt-4 glt-4 snf-3 snf-3 snf-11 snf-11 glt-6 glt-6 glt-3 glt-3 nac-3 nac-3 nac-1 nac-1 glt-1 glt-1 eat-4 eat-4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glt-5Amino acid transporter. (491 aa)
glt-7Amino acid transporter. (541 aa)
glt-4Putative sodium-dependent excitatory amino acid transporter glt-4; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D- aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. (499 aa)
snf-3Sodium- and chloride-dependent betaine transporter; Betaine transporter dependent on Na(+) and Cl(-) ions that functions primarily in the epidermis to clear betaine from the extracellular space. Elicits current in response to betaine but not in response to GABA, L-carnitine, sarcosine, glycine or dimethylglycine. Belongs to the sodium:neurotransmitter symporter (SNF) family. (600 aa)
snf-11Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (610 aa)
glt-6Putative sodium-dependent excitatory amino acid transporter glt-6. (542 aa)
glt-3Putative sodium-dependent excitatory amino acid transporter glt-3. (532 aa)
nac-3Sodium-dependent high-affinity dicarboxylate transporter 3; High-affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates. Plays a role in the regulation of life span. (566 aa)
nac-1Sodium-dependent low-affinity dicarboxylate transporter 1; Low affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates. Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. (582 aa)
glt-1Excitatory amino acid transporter; Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium (By similarity). (503 aa)
eat-4Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior. (576 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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