Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| B0334.5 | emc-5 | B0334.5.1 | B0334.15.1 | Uncharacterized protein. | EMC Endoplasmic Membrane protein Complex (Yeast EMC) homolog. | 0.608 |
| F41H10.4 | rab-10 | F41H10.4.1 | T23H2.5.2 | Uncharacterized protein. | Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for basolateral endocytic recycling, the return of macromolecules and fluid from endosomes to the plasma membrane, in polarized epithelial cells of the intestine upstream of rm [...] | 0.453 |
| F41H10.4 | rab-5 | F41H10.4.1 | F26H9.6.1 | Uncharacterized protein. | RAB family. | 0.500 |
| F41H10.4 | snx-3 | F41H10.4.1 | W06D4.5.1 | Uncharacterized protein. | PX domain-containing protein. | 0.471 |
| F41H10.4 | vps-18 | F41H10.4.1 | W06B4.3.1 | Uncharacterized protein. | Vacuolar protein sorting-associated protein 18 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion (By similarity). The HOPS complex is proposed to be recruited to [...] | 0.499 |
| F41H10.4 | vps-41 | F41H10.4.1 | F32A6.3c.1 | Uncharacterized protein. | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act in part as a core component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane [...] | 0.901 |
| W09C5.7 | ocrl-1 | W09C5.7a.1 | C16C2.3a.1 | SAC domain-containing protein. | Rho-GAP domain-containing protein. | 0.949 |
| Y37D8A.25 | ocrl-1 | Y37D8A.25.1 | C16C2.3a.1 | PH domain-containing protein. | Rho-GAP domain-containing protein. | 0.917 |
| Y57G11C.22 | plr-1 | Y57G11C.22a.1 | Y47D3B.11.1 | Uncharacterized protein. | Probable E3 ubiquitin-protein ligase plr-1; Probable E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled (By similarity). Acts on both canonical and non- canonical Wnt signaling pathway (By similarity). Plays a role in the migration and axon guidance of different neuronal cell types including CAN, HSN, AVK and AVG. Promotes the differentiation and regulates the anteroposterior polarity of AVG unpaired interneurons by sequestering the [...] | 0.424 |
| ZK632.12 | snx-27 | ZK632.12.1 | F25H2.2.1 | Uncharacterized protein ZK632.12. | Sorting NeXin. | 0.461 |
| aka-1 | snx-13 | D1022.7b.2 | Y116A8C.26a.2 | FYVE-type domain-containing protein. | Sorting NeXin. | 0.457 |
| aka-1 | wdfy-2 | D1022.7b.2 | D2013.2.2 | FYVE-type domain-containing protein. | WD repeat and FYVE domain-containing protein 2; Plays a role in coelomocyte endocytosis. | 0.603 |
| chat-1 | rab-10 | R08C7.2a.2 | T23H2.5.2 | CDC50 family protein chat-1; Probable chaperone protein for the phospholipid-transporting ATPase tat-1. Regulates cell membrane structure and function. Plays a role in maintaining the membrane phosphatidylserine asymmetry and the formation of the tubular membrane structure. Involved in membrane trafficking and is specifically involved in the recycling and degradation of endocytic cargo and this is likely with the phospholipid-transporting ATPase tat-1. | Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for basolateral endocytic recycling, the return of macromolecules and fluid from endosomes to the plasma membrane, in polarized epithelial cells of the intestine upstream of rm [...] | 0.483 |
| chat-1 | rme-1 | R08C7.2a.2 | W06H8.1b.2 | CDC50 family protein chat-1; Probable chaperone protein for the phospholipid-transporting ATPase tat-1. Regulates cell membrane structure and function. Plays a role in maintaining the membrane phosphatidylserine asymmetry and the formation of the tubular membrane structure. Involved in membrane trafficking and is specifically involved in the recycling and degradation of endocytic cargo and this is likely with the phospholipid-transporting ATPase tat-1. | Receptor Mediated Endocytosis; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.637 |
| chat-1 | tat-1 | R08C7.2a.2 | Y49E10.11c.1 | CDC50 family protein chat-1; Probable chaperone protein for the phospholipid-transporting ATPase tat-1. Regulates cell membrane structure and function. Plays a role in maintaining the membrane phosphatidylserine asymmetry and the formation of the tubular membrane structure. Involved in membrane trafficking and is specifically involved in the recycling and degradation of endocytic cargo and this is likely with the phospholipid-transporting ATPase tat-1. | Phospholipid-transporting ATPase tat-1; Transports phosphatidylserine from the outer to the inner leaflet of the plasma membrane, thereby maintaining the enrichment of this phospholipid in the inner leaflet. Ectopic exposure of phosphatidylserine on the cell surface may result in removal of living cells by neighboring phagocytes. Regulation of the phosphatidylserine distribution in plasma membranes is likely to help in the maintainence and control of the membrane surface charge. Plays a role in the formation of the tubular membrane structure and in membrane trafficking and is specifica [...] | 0.617 |
| clh-5 | vps-33.1 | C07H4.2.1 | B0303.9.1 | Chloride channel protein. | Vacuolar protein sorting-associated protein 33A; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways. Believed to act as a component of the putative HOPS endosomal tethering complex which is proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE- mediated membrane fusion. The HOPS complex is proposed to be recruited to rab-7 on the late endosomal membrane and to regulate lat [...] | 0.413 |
| cnt-1 | rab-35 | Y17G7B.15a.1 | Y47D3A.25.1 | Arf-GAP with ANK repeat and PH domain-containing protein cnt-1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Regulates endosome recycling downstream of rab-10 and upstream of arf-6. | RAB family. | 0.953 |
| cnt-1 | rab-5 | Y17G7B.15a.1 | F26H9.6.1 | Arf-GAP with ANK repeat and PH domain-containing protein cnt-1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Regulates endosome recycling downstream of rab-10 and upstream of arf-6. | RAB family. | 0.493 |
| cup-2 | snx-1 | F25D7.1.1 | C05D9.1.1 | Derlin-1; Specifically required for the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Belongs to the derlin family. | PX domain-containing protein. | 0.773 |
| ddl-2 | snx-27 | Y48E1B.1.1 | F25H2.2.1 | WASH_WAHD domain-containing protein. | Sorting NeXin. | 0.444 |
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