STRINGSTRING
ile-1 ile-1 nucb-1 nucb-1 erp-44.3 erp-44.3 sft-4 sft-4 erp-44.1 erp-44.1 C26C6.9 C26C6.9 gbf-1 gbf-1 C18B12.6 C18B12.6 sec-22 sec-22 yif-1 yif-1 F47G9.1 F47G9.1 sec-16 sec-16 erp-44.2 erp-44.2 B0511.13 B0511.13 gna-1 gna-1 Y73B6BL.36 Y73B6BL.36 tfg-1 tfg-1 Y60A3A.9 Y60A3A.9 trpp-5 trpp-5 Y47G6A.7 Y47G6A.7 Y102A11A.6 Y102A11A.6 sel-9 sel-9 gna-2 gna-2 T14G10.5 T14G10.5 T08D2.1 T08D2.1 ile-2 ile-2 T02E1.7 T02E1.7 R07E5.19 R07E5.19 erv-46 erv-46 K08E4.6 K08E4.6 F57B10.5 F57B10.5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ile-1L-type lectin-like domain-containing protein. (492 aa)
nucb-1NUCleoBindin homolog. (467 aa)
erp-44.3Thioredoxin domain-containing protein. (434 aa)
sft-4Surfeit locus protein 4 homolog; Belongs to the SURF4 family. (277 aa)
erp-44.1Thioredoxin domain-containing protein. (411 aa)
C26C6.9GOLD domain-containing protein. (217 aa)
gbf-1SEC7 domain-containing protein. (1975 aa)
C18B12.6Uncharacterized protein. (428 aa)
sec-22Yeast SEC homolog; Belongs to the synaptobrevin family. (214 aa)
yif-1YIP1-Interacting Factor homolog. (380 aa)
F47G9.1GOLD domain-containing protein. (204 aa)
sec-16Protein transport protein Sec16. (1232 aa)
erp-44.2Endoplasmic reticulum resident protein 44.2. (413 aa)
B0511.13Metallophosphoesterase 1 homolog; Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI- anchor proteins; Belongs to the metallophosphoesterase superfamily. MPPE1 family. (365 aa)
gna-1Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (165 aa)
Y73B6BL.36GOLD domain-containing protein. (222 aa)
tfg-1PB1 domain-containing protein. (486 aa)
Y60A3A.9GOLD domain-containing protein. (211 aa)
trpp-5Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi; Belongs to the TRAPP small subunits family. BET3 subfamily. (185 aa)
Y47G6A.7TPT domain-containing protein. (410 aa)
Y102A11A.6Uncharacterized protein. (286 aa)
sel-9Suppressor/enhancer of lin-12 protein 9; May have a role in the negative regulation of lin-12 and glp- 1 transport to the cell surface. May also have a role in a quality control mechanism for endoplasmic reticulum-Golgi transport; the budding of coatomer-coated and other species of coated vesicles, could bind cargo molecules to collect them into budding vesicles. Involved in regulating the expression of proteasomal subunits such as rpt-3 in order to confer resistance to proteasomal dysfunction. Belongs to the EMP24/GP25L family. (203 aa)
gna-2Glucosamine 6-phosphate N-acetyltransferase; Belongs to the acetyltransferase family. GNA1 subfamily. (347 aa)
T14G10.5Probable coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). (885 aa)
T08D2.1GOLD domain-containing protein. (167 aa)
ile-2L-type lectin-like domain-containing protein. (347 aa)
T02E1.7Uncharacterized protein T02E1.7; Belongs to the SURF4 family. (269 aa)
R07E5.19Vacuolar ATPase assembly integral membrane protein VMA21 homolog; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum; Belongs to the VMA21 family. (102 aa)
erv-46Yeast ERV (ER to Golgi transport Vesicle protein) homolog. (380 aa)
K08E4.6GOLD domain-containing protein. (234 aa)
F57B10.5GOLD domain-containing protein. (203 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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