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mvb-12 | MVB (Yeast MultiVesicular Body sorting factor) related. (277 aa) | ||||
rab-7 | RAB family. (209 aa) | ||||
cup-5 | PKD_channel domain-containing protein. (668 aa) | ||||
K11H3.4 | Uncharacterized protein K11H3.4. (364 aa) | ||||
sand-1 | SAND endocytosis protein family. (459 aa) | ||||
vps-52 | Vacuolar protein sorting-associated protein 52 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi. Plays a role in the trafficking of cargo to dense-core vesicles, probably through association with the EARP-interacting protein eipr-1. Important for neuronal function. Belongs to the VPS52 family. (702 aa) | ||||
stam-1 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. (457 aa) | ||||
gop-1 | Protein CLEC16A homolog; Regulator of mitophagy. (892 aa) | ||||
stg-1 | STarGazin (Mammalian calcium channel) homolog. (366 aa) | ||||
tsg-101 | Tumor Susceptibility Gene homolog. (425 aa) | ||||
haf-4 | HAlF transporter (PGP related). (787 aa) | ||||
snpn-1 | SNAPIN protein homolog; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in gut granule biogenesis. Belongs to the SNAPIN family. (122 aa) | ||||
vps-51 | Vacuolar protein sorting-associated protein 51 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi. Plays a role in the trafficking of cargo to dense-core vesicles, probably through association with the EARP-interacting protein eipr-1. Important for neuronal function. Belongs to the VPS51 family. (700 aa) | ||||
ZK632.12 | Uncharacterized protein ZK632.12. (266 aa) | ||||
haf-9 | ABC transmembrane type-1 domain-containing protein. (815 aa) | ||||
arl-8 | Novel small G protein indispensable for equal chromosome segregation; Belongs to the small GTPase superfamily. Arf family. (185 aa) | ||||
apd-3 | AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family. (1251 aa) | ||||
vps-18 | Vacuolar protein sorting-associated protein 18 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the rab-5-to-rab-7 endosome conversion probably implicating sand-1, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion (By similarity). The HOPS complex is proposed to be recruited to [...] (1026 aa) |