STRINGSTRING
cdh-12 cdh-12 casy-1 casy-1 zig-3 zig-3 rig-6 rig-6 cdh-10 cdh-10 rig-3 rig-3 ncam-1 ncam-1 cdh-5 cdh-5 fmi-1 fmi-1 him-4 him-4 cdh-8 cdh-8 cdh-4 cdh-4 wrk-1 wrk-1 zig-2 zig-2 zig-7 zig-7 cdh-9 cdh-9 zig-1 zig-1 zig-12 zig-12 cdh-7 cdh-7 cdh-1 cdh-1 igdb-3 igdb-3 hmr-1 hmr-1 zig-11 zig-11 cdh-3 cdh-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdh-12CaDHerin family. (2904 aa)
casy-1CAlSYntenin/Alcadein homolog. (984 aa)
zig-3Zwei Ig domain protein zig-3; Required for maintaining axon position of PVQ and PVP neurons postembryonically in the ventral nerve cord (VNC) by preventing axons drifting into the opposite side of the VNC that could occur during body growth and movement. (251 aa)
rig-6Contactin rig-6; Probable cell adhesion protein involved in patterning of the nervous system, playing a role in ALM and PLM touch receptor axon growth and VNC axon navigation. By associating with the transmembrane protein sax-7, mediates axonal interactions to establish synaptic connections between the AVG interneuron and the two PHC sensory neurons. Also required for non-neuronal cell migration in the excretory canal, regulating excretory canal elongation and excretory cell morphogenesis. Plays a role in regulating male mating behavior. (1196 aa)
cdh-10CaDHerin family. (1775 aa)
rig-3Neuronal immunoglobulin domain-containing protein rig-3; Cell surface protein which plays a role in the plasticity of cholinergic synapses at neuromuscular junctions and in the polarity of the mechanosensory neuron ALM, possibly by antagonizing Wnt signaling. (487 aa)
ncam-1NCAM (Neural cell adhesion molecule) homolog. (955 aa)
cdh-5CaDHerin family. (1449 aa)
fmi-1FlaMIngo (Cadherin plus 7TM domain) homolog. (2596 aa)
him-4EGF-like domain-containing protein. (5213 aa)
cdh-8CaDHerin family. (1684 aa)
cdh-4Cadherin-4; Potential calcium-dependent cell-adhesion protein that controls axon guidance in the ventral cord. (4328 aa)
wrk-1Wrapper/Rega-1/Klingon homolog. (452 aa)
zig-2Zwei Ig domain protein zig-2; Probably not involved in maintaining the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP, RMEV, AVK and HSN neurons. (238 aa)
zig-7Zwei Ig domain protein zig-7; Probably not involved in maintaining the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP, RMEV, AVK and HSN neurons. (239 aa)
cdh-9CaDHerin family. (623 aa)
zig-1Zwei Ig domain protein zig-1; Probably not involved in maintaining the position of ASI and ASH head neuron cell bodies and ventral nerve cord axons of PVQ, PVP, RMEV, AVK and HSN neurons. (265 aa)
zig-12Ig-like domain-containing protein. (197 aa)
cdh-7CaDHerin family. (1364 aa)
cdh-1CaDHerin family. (2779 aa)
igdb-3IG (Immunoglobulin) and DB (Cys-rich) domains. (547 aa)
hmr-1Cadherin-related hmr-1; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Required for adherens junction assembly and connecting adherens junctions to the cytoskeleton. Isoform b is involved in axonal guidance in a subset of motor neurons. (2920 aa)
zig-11Ig-like domain-containing protein. (304 aa)
cdh-3Cadherin-3; Cell adhesion protein involved in the control of epithelial morphogenesis. Together with metalloproteinase zmp-1 and hemicentin him-4, plays a role in anchor cell (AC) invasion during postembryonic vulval development. (3361 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.