STRINGSTRING
snt-5 snt-5 snt-6 snt-6 DH11.5 DH11.5 sue-1 sue-1 snt-1 snt-1 snt-2 snt-2 cla-1 cla-1 dop-2 dop-2 snt-7 snt-7 snt-4 snt-4 T27E4.1 T27E4.1 snt-3 snt-3 asic-1 asic-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
snt-5SyNapTotagmin. (458 aa)
snt-6C2 domain-containing protein. (373 aa)
DH11.5C2 domain-containing protein. (825 aa)
sue-1SUppressor of Elongation defect. (537 aa)
snt-1Synaptotagmin-1; May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone (By similarity). Involved in necrotic cell death. (443 aa)
snt-2Synaptotagmin 2; Ca(2+) sensor involved in Ca(2+)-dependent secretion of the nlp-40 neuropeptide from intestinal cells. Involved in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds. (369 aa)
cla-1Protein clarinet; Required for synapse development in the active zone of presynaptic terminals of specific neurons including serotonergic NSM neurons. The active zone is a protein-dense neuronal region within the presynaptic bouton, from which synaptic vesicles send neurotransmitter signals across the synapse. Plays a role in the recruitment and clustering of synaptic vesicles in the active zone of presynaptic terminals in serotonergic NSM neurons, and coordinates the release of synaptic vesicles at presynaptic terminals to regulate neurotransmission at neuromuscular junctions. Regulat [...] (8922 aa)
dop-2G_PROTEIN_RECEP_F1_2 domain-containing protein. (849 aa)
snt-7C2 domain-containing protein. (416 aa)
snt-4SyNapTotagmin. (381 aa)
T27E4.1Uncharacterized protein. (309 aa)
snt-3SyNapTotagmin. (284 aa)
asic-1Degenerin-like protein asic-1; Proton-gated cation channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions (By similarity). (823 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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