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| | ncx-4 | Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (596 aa) |
| | B0303.11 | Uncharacterized amino-acid permease B0303.11. (927 aa) |
| | eat-6 | Sodium/potassium-transporting ATPase subunit alpha. (996 aa) |
| | nhx-1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (514 aa) |
| | nhx-2 | Na(+)/H(+) exchanger protein 2; Na(+)/H(+) antiporter that promotes normal di- or tripeptide transporter function, recovery following the peptide-induced acidification of the intestinal cytoplasm and maintenance of the peptide-dependent intestinal pH homeostasis. Regulator of free fatty acid uptake from the diet together with the dipeptide transporter pept- 1. May play a timekeeper role in defecation cycle but is not necessary for pbo-4-dependent proton release. May play a role in the regulation of lifespan independent of the stress response pathway. (644 aa) |
| | catp-4 | Sodium/potassium-transporting ATPase subunit alpha. (1015 aa) |
| | catp-2 | Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1050 aa) |
| | ncx-7 | Putative sodium/calcium exchanger 7. (672 aa) |
| | ncx-6 | Putative sodium/calcium exchanger 6. (590 aa) |
| | catp-3 | Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1054 aa) |
| | ncx-2 | Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (975 aa) |
| | del-8 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (553 aa) |
| | glt-1 | Excitatory amino acid transporter; Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium (By similarity). (503 aa) |
| | ncx-8 | Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (703 aa) |
| | ncx-9 | Mitochondrial sodium/calcium exchanger protein; Mitochondrial sodium/calcium antiporter that mediates sodium- dependent calcium efflux from mitochondrion, thereby acting as a key regulator of mitochondrion calcium homeostasis (Probable). Required for patterning of neural circuits: functions in the same pathway as RAC- dependent effectors of the unc-6/netrin signaling pathway to set left/ right patterning of the VD/DD GABAergic circuit. Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily. (701 aa) |
| | del-9 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (579 aa) |
| | delm-2 | DEgenerin Linked to Mechanosensation; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (608 aa) |
| | acd-1 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (635 aa) |
| | acd-2 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (693 aa) |
| | acd-3 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (484 aa) |
| | unc-105 | Degenerin-like protein unc-105; Ion channel which is permeable to small monovalent cations. Shown not to be H+-ion gated. May be mechanosensitive and is required for growth and muscle development; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (962 aa) |
| | del-7 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (614 aa) |
| | deg-1 | Degenerin deg-1; Probable sodium channel subunit. Required by a subset of neurons. (778 aa) |
| | cho-1 | High-affinity choline transporter 1; Imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion and chloride ion dependent. (576 aa) |
| | cca-1 | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1885 aa) |
| | nhx-3 | Probable Na(+)/H(+) antiporter nhx-3; Plays a role in epithelial membrane transport processes. (670 aa) |
| | del-1 | Degenerin del-1; Probable sodium channel subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (694 aa) |
| | flr-1 | FLR-1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (638 aa) |
| | nhx-4 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (749 aa) |
| | mec-2 | Mechanosensory protein 2; Positively regulates the activity of the putative mechanosensory transduction channel. May link the mechanosensory channel and the microtubule cytoskeleton of the touch receptor neurons. Required for the function of a set of six touch receptor neurons. (1239 aa) |
| | mec-10 | Degenerin mec-10; Amiloride-sensitive sodium channel subunit required for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior. (724 aa) |
| | delm-1 | DEgenerin Linked to Mechanosensation; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (626 aa) |
| | degt-1 | DEGenerin-related Touch-involved channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (852 aa) |
| | del-3 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (487 aa) |
| | slc-28.1 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (568 aa) |
| | slc-28.2 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (575 aa) |
| | acd-4 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (613 aa) |
| | nac-1 | Sodium-dependent low-affinity dicarboxylate transporter 1; Low affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates. Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. (582 aa) |
| | abts-1 | Anion exchange protein. (1215 aa) |
| | egas-4 | EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (883 aa) |
| | nhx-5 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (630 aa) |
| | nhx-6 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (634 aa) |
| | F58G6.8 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (198 aa) |
| | del-5 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (526 aa) |
| | nac-3 | Sodium-dependent high-affinity dicarboxylate transporter 3; High-affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates. Plays a role in the regulation of life span. (566 aa) |
| | glt-3 | Putative sodium-dependent excitatory amino acid transporter glt-3. (532 aa) |
| | pbo-4 | Na(+)/H(+) exchanger protein 7; Na+/H+ exchanger which mediates the transient acidification of the coelomic space and plays a role in contraction of posterior body muscles during defecation. Probably by regulating the defecation motor program, required for fatty acid uptake by intestinal cells. (783 aa) |
| | snf-6 | Sodium-dependent acetylcholine transporter; Mediates sodium-dependent uptake of acetylcholine at neuromuscular junctions during periods of increased synaptic activity, may also prevent spillover to adjacent synaptic sites. Not involved in the uptake of other neurotransmitters (GABA, glycine, proline and glutamate) and there was also no inhibition of uptake by adding an excess of other candidate substrates (GABA, glycine, taurine, creatine, proline, alanine, carnitine, glutamate and betaine). Required for muscle integrity; altered transport of acetylcholine due to loss of dystrophin-gly [...] (714 aa) |
| | glt-6 | Putative sodium-dependent excitatory amino acid transporter glt-6. (542 aa) |
| | unc-8 | Degenerin unc-8. (778 aa) |
| | mec-4 | Degenerin mec-4; Probable sodium channel subunit. May be needed for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior. (768 aa) |
| | snf-11 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (610 aa) |
| | snf-3 | Sodium- and chloride-dependent betaine transporter; Betaine transporter dependent on Na(+) and Cl(-) ions that functions primarily in the epidermis to clear betaine from the extracellular space. Elicits current in response to betaine but not in response to GABA, L-carnitine, sarcosine, glycine or dimethylglycine. Belongs to the sodium:neurotransmitter symporter (SNF) family. (600 aa) |
| | tmc-1 | Transmembrane channel-like protein 1; Sodium-sensor ion channel that acts specifically in salt taste chemosensation. Required for salt-evoked neuronal activity and behavioral avoidance of high concentrations of NaCl. Belongs to the TMC family. (1285 aa) |
| | del-6 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (577 aa) |
| | glt-4 | Putative sodium-dependent excitatory amino acid transporter glt-4; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D- aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. (499 aa) |
| | dat-1 | Sodium-dependent dopamine transporter; Dopamine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. (615 aa) |
| | del-4 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (527 aa) |
| | del-10 | Degenerin-like protein del-10. (1069 aa) |
| | acd-5 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (714 aa) |
| | asic-2 | Degenerin-like protein asic-2. (545 aa) |
| | cat-1 | MFS domain-containing protein. (553 aa) |
| | mec-6 | Mechanosensory abnormality protein 6; Probable touch-cell sodium channel subunit. May be needed for mechanosensory transduction (touch sensitivity). Interacts with degenerin channel proteins and stabilizes the channel. Non-voltage- gated amiloride-sensitive cation channel permeable for sodium, potassium, lithium and N-methylglucamine. Belongs to the paraoxonase family. (377 aa) |
| | glt-7 | Amino acid transporter. (541 aa) |
| | catp-1 | Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1121 aa) |
| | ncx-1 | Sodium-calcium exchanger; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (880 aa) |
| | nhx-8 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (681 aa) |
| | ncx-5 | Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (656 aa) |
| | nkcc-1 | Na-K-Cl Cotransporter homolog. (1235 aa) |
| | glt-5 | Amino acid transporter. (491 aa) |
| | mod-5 | Transporter. (671 aa) |
| | Y57G11C.44 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (155 aa) |
| | egas-1 | EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (938 aa) |
| | egas-2 | EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (919 aa) |
| | egas-3 | EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (921 aa) |
| | ncx-10 | Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (668 aa) |
| | ncx-3 | Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (830 aa) |
| | eat-4 | Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior. (576 aa) |
| | ZK563.2 | Uncharacterized protein. (573 aa) |
| | asic-1 | Degenerin-like protein asic-1; Proton-gated cation channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions (By similarity). (823 aa) |
| | nhx-9 | Probable Na(+)/H(+) antiporter nhx-9; Serves some physiological function other than regulation of cellular pH. (667 aa) |
