STRINGSTRING
sfxn-1.5 sfxn-1.5 glt-4 glt-4 sfxn-1.3 sfxn-1.3 glt-5 glt-5 glt-7 glt-7 sfxn-2 sfxn-2 sfxn-1.1 sfxn-1.1 glt-1 glt-1 sfxn-1.2 sfxn-1.2 sfxn-1.4 sfxn-1.4 glt-3 glt-3 glt-6 glt-6 unc-47 unc-47
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sfxn-1.5Sidoreflexin. (324 aa)
glt-4Putative sodium-dependent excitatory amino acid transporter glt-4; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D- aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. (499 aa)
sfxn-1.3Sidoreflexin. (329 aa)
glt-5Amino acid transporter. (491 aa)
glt-7Amino acid transporter. (541 aa)
sfxn-2Sidoreflexin. (319 aa)
sfxn-1.1Sideroflexin-1.1; Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. Belongs to the sideroflexin family. (329 aa)
glt-1Excitatory amino acid transporter; Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium (By similarity). (503 aa)
sfxn-1.2Sidoreflexin. (328 aa)
sfxn-1.4Sidoreflexin. (326 aa)
glt-3Putative sodium-dependent excitatory amino acid transporter glt-3. (532 aa)
glt-6Putative sodium-dependent excitatory amino acid transporter glt-6. (542 aa)
unc-47Vesicular GABA transporter; Involved in the uptake of GABA into the synaptic vesicles. Belongs to the amino acid/polyamine transporter 2 family. (486 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (22%) [HD]