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| | kcc-1 | K+/Cl-Cotransporter. (1156 aa) |
| | ant-1.2 | Adenine Nucleotide Translocator; Belongs to the mitochondrial carrier (TC 2.A.29) family. (300 aa) |
| | cat-1 | MFS domain-containing protein. (553 aa) |
| | sulp-6 | STAS domain-containing protein. (823 aa) |
| | ant-1.1 | Adenine Nucleotide Translocator; Belongs to the mitochondrial carrier (TC 2.A.29) family. (300 aa) |
| | T26C5.3 | Uncharacterized protein. (607 aa) |
| | snf-12 | Transporter. (1022 aa) |
| | dat-1 | Sodium-dependent dopamine transporter; Dopamine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. (615 aa) |
| | glt-4 | Putative sodium-dependent excitatory amino acid transporter glt-4; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D- aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. (499 aa) |
| | nstp-9 | TPT domain-containing protein. (315 aa) |
| | unc-47 | Vesicular GABA transporter; Involved in the uptake of GABA into the synaptic vesicles. Belongs to the amino acid/polyamine transporter 2 family. (486 aa) |
| | snf-3 | Sodium- and chloride-dependent betaine transporter; Betaine transporter dependent on Na(+) and Cl(-) ions that functions primarily in the epidermis to clear betaine from the extracellular space. Elicits current in response to betaine but not in response to GABA, L-carnitine, sarcosine, glycine or dimethylglycine. Belongs to the sodium:neurotransmitter symporter (SNF) family. (600 aa) |
| | vglu-3 | Potential vesicular glutamate transporter vglu-3. (544 aa) |
| | T05F1.8 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (393 aa) |
| | T04B8.5 | Uncharacterized protein. (952 aa) |
| | snf-11 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (610 aa) |
| | ant-1.4 | Mitochondrial adenine nucleotide translocase 1.4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa) |
| | ZK822.5 | Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (577 aa) |
| | nhx-9 | Probable Na(+)/H(+) antiporter nhx-9; Serves some physiological function other than regulation of cellular pH. (667 aa) |
| | ZK563.2 | Uncharacterized protein. (573 aa) |
| | eat-4 | Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior. (576 aa) |
| | sulp-8 | STAS domain-containing protein. (611 aa) |
| | snf-7 | Transporter. (705 aa) |
| | ncx-3 | Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (830 aa) |
| | ncx-10 | Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (668 aa) |
| | Y71G10AR.4 | Uncharacterized protein. (525 aa) |
| | Y70G10A.3 | Solute carrier organic anion transporter family member. (690 aa) |
| | mod-5 | Transporter. (671 aa) |
| | glt-5 | Amino acid transporter. (491 aa) |
| | hmit-1.2 | MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (613 aa) |
| | hmit-1.1 | MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (606 aa) |
| | Y47G6A.7 | TPT domain-containing protein. (410 aa) |
| | snf-5 | Sodium-dependent transporter snf-5; Sodium-dependent amino acid transporter that mediates the uptake of the L-enantiomers of various amino acids, including L-proline and L-methionine, and also of acidic amino acids such as L-glutamic acid and L-aspartic acid (Probable). May additionally have a role in potassium-dependent amino acid absorption. In response to the availability of amino acid nutrients, may play a role in dauer formation. May play a role in promoting fertility. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (728 aa) |
| | Y43D4A.1 | Uncharacterized protein. (91 aa) |
| | Y37B11A.3 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (125 aa) |
| | nkcc-1 | Na-K-Cl Cotransporter homolog. (1235 aa) |
| | ncx-5 | Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (656 aa) |
| | Y32F6B.1 | Solute carrier organic anion transporter family member. (760 aa) |
| | snf-10 | Transporter. (673 aa) |
| | nhx-8 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (681 aa) |
| | ncx-1 | Sodium-calcium exchanger; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (880 aa) |
| | pitr-6 | Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (485 aa) |
| | sulp-7 | STAS domain-containing protein. (582 aa) |
| | snf-1 | Sodium: Neurotransmitter symporter Family. (617 aa) |
| | glt-7 | Amino acid transporter. (541 aa) |
| | dif-1 | Protein dif-1; Seems to play a role in the maintenance of tissue differentiation in the developing embryo, but not for its initiation. (312 aa) |
| | F47E1.4 | Solute carrier organic anion transporter family member. (728 aa) |
| | F47E1.2 | Solute carrier organic anion transporter family member. (744 aa) |
| | F47B8.10 | MFS domain-containing protein. (456 aa) |
| | F41E7.2 | Na_H_Exchanger domain-containing protein. (558 aa) |
| | F41E7.1 | Na_H_Exchanger domain-containing protein. (516 aa) |
| | sulp-3 | Sulfate permease family protein 3; Possible sulfate transporter. (782 aa) |
| | ncx-4 | Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (596 aa) |
| | nac-1 | Sodium-dependent low-affinity dicarboxylate transporter 1; Low affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates. Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. (582 aa) |
| | slc-28.2 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (575 aa) |
| | slc-28.1 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (568 aa) |
| | F25B4.7 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (306 aa) |
| | F21G4.1 | Solute carrier organic anion transporter family member. (640 aa) |
| | F16H11.1 | Uncharacterized protein. (501 aa) |
| | sulp-2 | STAS domain-containing protein. (652 aa) |
| | nhx-4 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (749 aa) |
| | F10E7.9 | AA_permease domain-containing protein. (603 aa) |
| | pitr-5 | Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (509 aa) |
| | F01G4.6 | Phosphate carrier protein, mitochondrial; Transport of phosphate groups from the cytosol to the mitochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. (387 aa) |
| | sulp-1 | STAS domain-containing protein. (729 aa) |
| | nhx-3 | Probable Na(+)/H(+) antiporter nhx-3; Plays a role in epithelial membrane transport processes. (670 aa) |
| | sqv-7 | UDP-sugar transporter sqv-7; Involved in the import of UDP-glucuronic acid (UDP-GlcA), UDP-N-acetylgalactosamine (UDP-GalNAc) and UDP-galactose (UDP-Gal) from the cytoplasm into the Golgi lumen for the biosynthesis of glycoconjugates that play a pivotal role in development. Involved in the synthesis of chondroitin sulfate and heparan sulfate proteoglycans. Required for embryonic development. Involved in vulva epithelium invagination and embryonic development. Involved in the directed migration of hermaphrodite-specific neurons. Belongs to the TPT transporter family. SLC35D subfamily. (329 aa) |
| | nstp-10 | GDP-fucose transporter; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily. (363 aa) |
| | snf-9 | Transporter. (713 aa) |
| | cho-1 | High-affinity choline transporter 1; Imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion and chloride ion dependent. (576 aa) |
| | pitr-1 | Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (530 aa) |
| | C47E12.2 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (306 aa) |
| | C42C1.19 | MFS domain-containing protein. (403 aa) |
| | ctns-1 | Cystinosin homolog; Thought to transport cystine out of lysosomes (By similarity). May play a role in the degradation of engulfed apoptotic cells. (404 aa) |
| | slc-17.2 | Uncharacterized transporter slc-17.2. (493 aa) |
| | C33F10.12 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (392 aa) |
| | C14C10.1 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (334 aa) |
| | ncx-9 | Mitochondrial sodium/calcium exchanger protein; Mitochondrial sodium/calcium antiporter that mediates sodium- dependent calcium efflux from mitochondrion, thereby acting as a key regulator of mitochondrion calcium homeostasis (Probable). Required for patterning of neural circuits: functions in the same pathway as RAC- dependent effectors of the unc-6/netrin signaling pathway to set left/ right patterning of the VD/DD GABAergic circuit. Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily. (701 aa) |
| | ncx-8 | Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (703 aa) |
| | glt-1 | Excitatory amino acid transporter; Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium (By similarity). (503 aa) |
| | ncx-2 | Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (975 aa) |
| | C09E8.1 | Uncharacterized protein. (783 aa) |
| | clh-5 | Chloride channel protein. (797 aa) |
| | ncx-6 | Putative sodium/calcium exchanger 6. (590 aa) |
| | ncx-7 | Putative sodium/calcium exchanger 7. (672 aa) |
| | slc-17.3 | Uncharacterized transporter slc-17.3. (535 aa) |
| | nhx-2 | Na(+)/H(+) exchanger protein 2; Na(+)/H(+) antiporter that promotes normal di- or tripeptide transporter function, recovery following the peptide-induced acidification of the intestinal cytoplasm and maintenance of the peptide-dependent intestinal pH homeostasis. Regulator of free fatty acid uptake from the diet together with the dipeptide transporter pept- 1. May play a timekeeper role in defecation cycle but is not necessary for pbo-4-dependent proton release. May play a role in the regulation of lifespan independent of the stress response pathway. (644 aa) |
| | misc-1 | Mitochondrial 2-oxoglutarate/malate carrier protein; Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism (By similarity). Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae. Furthermore, plays a role in the oxidative stress response regulating endo [...] (306 aa) |
| | nhx-1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (514 aa) |
| | pitr-4 | Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (523 aa) |
| | B0303.11 | Uncharacterized amino-acid permease B0303.11. (927 aa) |
| | pitr-3 | Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (494 aa) |
| | pitr-2 | Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (494 aa) |
| | abts-1 | Anion exchange protein. (1215 aa) |
| | abts-2 | Anion/Bicarbonate TranSporter family. (737 aa) |
| | F52H2.4 | Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (486 aa) |
| | F53B1.8 | Solute carrier organic anion transporter family member. (801 aa) |
| | snf-2 | Transporter. (746 aa) |
| | nhx-5 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (630 aa) |
| | abts-3 | HCO3_cotransp domain-containing protein. (1043 aa) |
| | F57G8.5 | Na_H_Exchanger domain-containing protein. (498 aa) |
| | nhx-6 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (634 aa) |
| | kcc-2 | K+/Cl-Cotransporter. (1129 aa) |
| | bus-12 | JC8.12-like protein. (315 aa) |
| | ant-1.3 | Mitochondrial adenine nucleotide translocase 1.3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa) |
| | kcc-3 | Potassium/chloride cotransporter 3; Probable potassium/chloride cotransporter that functions in the amphid sheath glial cells to regulate thermotaxis behavior. By maintaining chloride homeostasis, negatively regulates guanylate cyclase gcy-8 in the thermosensory AFD neurons and thereby controls the microvilli receptive ending morphology of the AFD neurons and thermotaxis. Modulates the temperature-evoked neuronal activity of the AFD neurons such as calcium responses to temperature gradients. Might also play a role in the chemotaxis behavior mediated by the sensory neurons AWA and AWC. (1081 aa) |
| | mcu-1 | Calcium uniporter protein, mitochondrial; Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore- forming and calcium-conducting subunit (By similarity). Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways (By similarity). Required for rapid mitochondrial calcium uptake and mitochondrial reactive oxygen species (mtROS) production after wounding. (333 aa) |
| | nac-3 | Sodium-dependent high-affinity dicarboxylate transporter 3; High-affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates. Plays a role in the regulation of life span. (566 aa) |
| | glt-3 | Putative sodium-dependent excitatory amino acid transporter glt-3. (532 aa) |
| | pbo-4 | Na(+)/H(+) exchanger protein 7; Na+/H+ exchanger which mediates the transient acidification of the coelomic space and plays a role in contraction of posterior body muscles during defecation. Probably by regulating the defecation motor program, required for fatty acid uptake by intestinal cells. (783 aa) |
| | slc-25A10 | Oxoglutarate/malate carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (290 aa) |
| | K11H3.3 | Putative tricarboxylate transport protein, mitochondrial; Transport of citrate across inner mitochondrial membrane. Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa) |
| | sulp-4 | STAS domain-containing protein. (749 aa) |
| | sulp-5 | STAS domain-containing protein. (737 aa) |
| | hmit-1.3 | MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (604 aa) |
| | snf-6 | Sodium-dependent acetylcholine transporter; Mediates sodium-dependent uptake of acetylcholine at neuromuscular junctions during periods of increased synaptic activity, may also prevent spillover to adjacent synaptic sites. Not involved in the uptake of other neurotransmitters (GABA, glycine, proline and glutamate) and there was also no inhibition of uptake by adding an excess of other candidate substrates (GABA, glycine, taurine, creatine, proline, alanine, carnitine, glutamate and betaine). Required for muscle integrity; altered transport of acetylcholine due to loss of dystrophin-gly [...] (714 aa) |
| | abts-4 | Anion/Bicarbonate TranSporter family. (956 aa) |
| | glt-6 | Putative sodium-dependent excitatory amino acid transporter glt-6. (542 aa) |
| | R07E3.4 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | nac-2 | Sodium-dependent high-affinity dicarboxylate transporter 2; High-affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates (By similarity). Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. (585 aa) |
