STRINGSTRING
ptp-1 ptp-1 C29F5.1 C29F5.1 rnf-121 rnf-121 slc-17.1 slc-17.1 emc-2 emc-2 Y54E5A.5 Y54E5A.5 oig-2 oig-2 hpo-21 hpo-21 Y106G6A.1 Y106G6A.1 dgtr-1 dgtr-1 ndx-1 ndx-1 T03G6.3 T03G6.3 R151.10 R151.10 sca-1 sca-1 unc-68 unc-68 K08C7.6 K08C7.6 K07F5.22 K07F5.22 F57C2.5 F57C2.5 F44A2.5 F44A2.5 csq-1 csq-1 ccch-1 ccch-1 itr-1 itr-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ptp-1Tyrosine-protein phosphatase 1. (1026 aa)
C29F5.1Uncharacterized protein. (383 aa)
rnf-121RING finger protein 121; Required for the cessation of distal tip cell migration at the end of larval morphogenesis; Belongs to the RNF121 family. (335 aa)
slc-17.1MFS domain-containing protein. (479 aa)
emc-2TPR_REGION domain-containing protein. (294 aa)
Y54E5A.5Uncharacterized protein. (153 aa)
oig-2Ig-like domain-containing protein. (108 aa)
hpo-21Probable signal peptidase complex subunit 2; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. (180 aa)
Y106G6A.1Protein kinase domain-containing protein. (430 aa)
dgtr-1DGAT (Acyl-CoA:DiacylGlycerol AcylTransferase) Related. (359 aa)
ndx-1Putative nudix hydrolase 1; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. (365 aa)
T03G6.3Uncharacterized protein. (465 aa)
R151.10R151.8A protein. (233 aa)
sca-1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1059 aa)
unc-68Uncharacterized protein. (5202 aa)
K08C7.6Uncharacterized protein. (285 aa)
K07F5.22Protein kish; Involved in the early part of the secretory pathway. (73 aa)
F57C2.5Str_synth domain-containing protein. (391 aa)
F44A2.5MIF4G domain-containing protein. (390 aa)
csq-1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (417 aa)
ccch-1CCCH-type zinc finger putative transcription factor. (460 aa)
itr-1Inositol 1,4,5-trisphosphate receptor itr-1; Receptor for inositol 1,4,5-trisphosphate, a second messenger that regulates intracellular calcium homeostasis. Binds in vitro to both inositol 1,4,5-trisphosphate (1,4,5-InsP3) and inositol 2,4,5-trisphosphate (2,4,5-InsP3) with high affinity and does not discriminate between the phosphate at 1 or 2 position. Can also bind inositol 1,3,4,5-tetrakisphosphate (1,3,4,5-InsP4) and inositol 4,5-bisphosphate (4,5-InsP2), but with lower affinity. Acts as a timekeeper/rhythm generator via calcium signaling, affecting the defecation cycle and pharyn [...] (2892 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (12%) [HD]