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psd-1 | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (377 aa) | ||||
wrt-8 | Warthog protein 8 C-product; Intercellular signal essential for a variety of patterning events during development. (550 aa) | ||||
ced-3 | Cell death protein 3 subunit p13; Acts as a cysteine protease in controlling programmed cell death (apoptosis) by proteolytically activating or inactivating a wide range of substrates. Component of the egl-1, ced-9, ced-4 and ced-3 apoptotic signaling cascade required for the initiation of programmed cell death in cells fated to die during embryonic and postembryonic development. During oogenesis, required for germline apoptosis downstream of ced-9 and ced-4 but independently of egl-1. By cleaving and activating ced-8, promotes phosphatidylserine exposure on the surface of apoptotic ce [...] (503 aa) | ||||
myrf-2 | Myelin regulatory factor homolog 2, C-terminal; [Myelin regulatory factor homolog 2]: Constitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor homolog 2, N-terminal component that specifically activates transcription of genes involved in synaptic rewiring during nervous system maturation. [Myelin regulatory factor homolog 2, N-terminal]: Transcription factor that specifically activates expression of genes involved in synaptic rewiring during nervous system maturation. Specifically required for dorsal D (DD) GABA [...] (1009 aa) | ||||
grd-2 | GRounDhog (Hedgehog-like family). (946 aa) | ||||
mig-17 | Metalloprotease mig-17; Metalloprotease. Acts in the basement membrane to control directional migration of distal tip cells (DTCs) along the body wall basement membranes, a key step that promotes gonad morphogenesis. Regulates DTC migration probably by recruiting fibulin fbl-1, type IV collagen let-2 and nidogen nid-1 to the gonad basement membrane thereby promoting the remodeling of the basement membrane. During larval development and probably upstream of basement membrane proteins fbl-1, let-2 and nid-1, regulates pharynx length, probably by regulating pharyngeal cell length. Does no [...] (509 aa) | ||||
myrf-1 | Myelin regulatory factor homolog 1, C-terminal; [Myelin regulatory factor homolog 1]: Constitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor homolog 1, N-terminal component that specifically activates transcription of genes involved in synaptic rewiring during nervous system maturation. [Myelin regulatory factor homolog 1, N-terminal]: Transcription factor that specifically activates expression of genes involved in synaptic rewiring during nervous system maturation. Specifically required for dorsal D (DD) GABA [...] (931 aa) | ||||
grd-11 | GRounDhog (Hedgehog-like family). (977 aa) | ||||
tra-3 | Calpain-5; Required for the correct female sexual development of the soma and germline in hermaphrodite animals, while being fully dispensable in males. Has calcium-dependent proteolytic activity and is involved in the cleavage of tra-2, for which it acts as a potentiator. Capable of calcium-dependent autolysis. Part of the necrosis cell death pathway. Required for necrosis of intestinal cells induced by B.thuringiensis endotoxin Cry6Aa ; Belongs to the peptidase C2 family. (648 aa) | ||||
grd-1 | GRounDhog (Hedgehog-like family). (1160 aa) | ||||
qua-1 | Protein qua-1; Required for cuticle shedding and normal alae morphology and localization, and subsequently larval development. (1169 aa) | ||||
hog-1 | HOG only (Hedgehog Hog domain alone). (245 aa) | ||||
csp-1 | Caspase A subunit p14; Cysteine protease which, in vitro, cleaves itself and caspase ced-3 into their mature active forms. Also cleaves, in vitro, inactive caspase csp-2 isoform b. Required maternally to induce apoptosis in a subset of cells fated to die during embryogenesis, mostly independently of the ced-9, ced-4 and ced-3 canonical apoptosis pathway. Involved in the degeneration of dopaminergic CEP neurons in response to high Mn(2+) levels. (536 aa) | ||||
wrt-7 | WaRThog (Hedgehog-like family). (481 aa) | ||||
wrt-1 | Warthog protein 1 C-product; Intercellular signal essential for a variety of patterning events during development. (484 aa) | ||||
wrt-6 | Warthog protein 6 C-product; Intercellular signal essential for a variety of patterning events during development; Belongs to the hedgehog family. (593 aa) | ||||
wrt-4 | Warthog protein 4 C-product; Intercellular signal essential for a variety of patterning events during development. (557 aa) |