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B0024.13 B0024.13 dhcr-7 dhcr-7 ivd-1 ivd-1 acdh-6 acdh-6 sdha-1 sdha-1 C04E6.7 C04E6.7 art-1 art-1 acdh-2 acdh-2 dpyd-1 dpyd-1 acdh-13 acdh-13 sdha-2 sdha-2 acdh-5 acdh-5 C45G9.2 C45G9.2 acox-1.5 acox-1.5 acdh-1 acdh-1 acdh-12 acdh-12 acox-1.1 acox-1.1 acox-1.2 acox-1.2 acox-1.3 acox-1.3 acox-1.4 acox-1.4 F19H6.4 F19H6.4 acdh-9 acdh-9 fasn-1 fasn-1 F36A2.2 F36A2.2 sdhb-1 sdhb-1 F42F12.3 F42F12.3 F52H2.6 F52H2.6 F53C11.3 F53C11.3 F54D5.7 F54D5.7 acox-3 acox-3 acox-1.6 acox-1.6 glf-1 glf-1 acdh-8 acdh-8 acdh-3 acdh-3 acds-10 acds-10 M106.3 M106.3 pges-2 pges-2 decr-1.3 decr-1.3 mev-1 mev-1 acdh-10 acdh-10 acdh-4 acdh-4 acdh-7 acdh-7 decr-1.2 decr-1.2 dhod-1 dhod-1 mecr-1 mecr-1 Y37E11B.5 Y37E11B.5 acdh-11 acdh-11 Y48A6B.9 Y48A6B.9 dus-2 dus-2 Y7A5A.1 Y7A5A.1 ZK1251.3 ZK1251.3
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
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B0024.13Polyprenol reductase; Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N- glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism (By similarity). (309 aa)
dhcr-7DeHydroCholesterol Reductase. (457 aa)
ivd-1Isovaleryl-CoA dehydrogenase. (419 aa)
acdh-6Probable acyl-CoA dehydrogenase 6; Belongs to the acyl-CoA dehydrogenase family. (408 aa)
sdha-1Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (646 aa)
C04E6.7Uncharacterized protein. (241 aa)
art-1Probable very-long-chain enoyl-CoA reductase art-1; Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precurso [...] (308 aa)
acdh-2Acyl CoA DeHydrogenase. (386 aa)
dpyd-1Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity). Involved in the degradation of the chemotherapeutic drug 5-fluorouracil. (1059 aa)
acdh-13Acyl CoA DeHydrogenase. (617 aa)
sdha-2Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (640 aa)
acdh-5Acyl CoA DeHydrogenase. (442 aa)
C45G9.2Uncharacterized tRNA-dihydrouridine synthase-like protein C45G9.2; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs; Belongs to the Dus family. (284 aa)
acox-1.5Probable peroxisomal acyl-coenzyme A oxidase 1.5; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. (659 aa)
acdh-1Acyl CoA DeHydrogenase. (427 aa)
acdh-12Acyl CoA DeHydrogenase. (613 aa)
acox-1.1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (674 aa)
acox-1.2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
acox-1.3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa)
acox-1.4Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (662 aa)
F19H6.43-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (243 aa)
acdh-9Acyl CoA DeHydrogenase. (409 aa)
fasn-1Carrier domain-containing protein. (2613 aa)
F36A2.2Uncharacterized protein. (527 aa)
sdhb-1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (298 aa)
F42F12.33-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (243 aa)
F52H2.6Diminuto-like protein; Belongs to the DIMINUTO family. (525 aa)
F53C11.3Uncharacterized oxidoreductase F53C11.3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily. (313 aa)
F54D5.7Probable glutaryl-CoA dehydrogenase, mitochondrial. (409 aa)
acox-3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (667 aa)
acox-1.6Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (667 aa)
glf-1Amino_oxidase domain-containing protein. (476 aa)
acdh-8Acyl CoA DeHydrogenase. (412 aa)
acdh-3Acyl CoA DeHydrogenase. (419 aa)
acds-10ACaD (ACAD, acyl-CoA Dehydrogenase) Sequence homolog. (985 aa)
M106.3PKS_ER domain-containing protein. (373 aa)
pges-2ProstaGlandin E Synthase homolog. (347 aa)
decr-1.3Probable 2,4-dienoyl-CoA reductase 3; Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily. (309 aa)
mev-1Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). Mediates resistance to enteropathogenic E.coli infection. Belongs to the cytochrome b560 family. (182 aa)
acdh-10Probable medium-chain specific acyl-CoA dehydrogenase 10, mitochondrial; This enzyme is specific for acyl chain lengths of 4 to 16. Belongs to the acyl-CoA dehydrogenase family. (417 aa)
acdh-4Acyl CoA DeHydrogenase. (385 aa)
acdh-7Acyl CoA DeHydrogenase. (412 aa)
decr-1.2Probable 2,4-dienoyl-CoA reductase decr-1.2; Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily. (309 aa)
dhod-1Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (411 aa)
mecr-1Enoyl-[acyl-carrier-protein] reductase, mitochondrial; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. (344 aa)
Y37E11B.5tRNA-dihydrouridine(47) synthase [NAD(P)(+)]. (554 aa)
acdh-11Acyl-CoA dehydrogenase family member 11; Promotes adaption to elevated temperatures by regulating expression of the lipid desaturase, fat-7. Binds selectively and with high affinity to fatty acids with chain lengths from C10 to C12 and prevents them from activating fat-7 expression mediated by the nuclear hormone receptor nhr-49, leading to low levels of membrane lipid desaturation and membrane fluidity for adaption to heat. (617 aa)
Y48A6B.9Enoyl-[acyl-carrier-protein] reductase, mitochondrial; Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. (346 aa)
dus-2DRBM domain-containing protein. (436 aa)
Y7A5A.1FAD-binding PCMH-type domain-containing protein. (538 aa)
ZK1251.33-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (253 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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