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| | nstp-4 | Nucleotide Sugar TransPorter family. (339 aa) |
| | nstp-5 | Nucleotide Sugar TransPorter family. (390 aa) |
| | cnx-1 | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (By similarity). Required for embryogenesis and larval development under heat and ER stress conditions. May be important for germ cell development. Involved in neuronal necrotic cell death. (619 aa) |
| | perm-3 | ER membrane protein complex subunit 4; Belongs to the EMC4 family. (174 aa) |
| | eat-4 | Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior. (576 aa) |
| | tomm-70 | Mitochondrial import receptor subunit tomm-70; Receptor that accelerates the import of all mitochondrial precursor proteins; Belongs to the Tom70 family. (554 aa) |
| | ugtp-1 | UDP-galactose translocator 1. (355 aa) |
| | fitm-2 | FIT family protein fitm-2. (283 aa) |
| | unc-17 | Vesicular acetylcholine transporter unc-17; Involved in acetylcholine transport into synaptic vesicles. Belongs to the major facilitator superfamily. Vesicular transporter family. (532 aa) |
| | nstp-3 | Nucleotide Sugar TransPorter family. (344 aa) |
| | sfxn-1.3 | Sidoreflexin. (329 aa) |
| | emc-3 | ER membrane protein complex subunit 3. (234 aa) |
| | nbet-1 | t-SNARE coiled-coil homology domain-containing protein. (107 aa) |
| | emc-2 | TPR_REGION domain-containing protein. (294 aa) |
| | Y56A3A.36 | DOLichol Kinase. (299 aa) |
| | cox-18 | Cytochrome OXidase assembly protein. (317 aa) |
| | rbm-39 | RNA Binding Motif protein homolog. (580 aa) |
| | pign-1 | PigN domain-containing protein. (912 aa) |
| | elo-9 | Elongation of very long chain fatty acids protein. (286 aa) |
| | Y53F4B.14 | Uncharacterized protein. (90 aa) |
| | spg-7 | AFG3-like protein spg-7; Acts as a component of the m-AAA protease complex which is an ATP-dependent metalloprotease mediating degradation of non-assembled mitochondrial inner membrane proteins (By similarity). The complex is necessary for the assembly of mitochondrial respiratory chain and ATPase complexes (By similarity). Functions both in post-translational assembly and in the turnover of mistranslated or misfolded polypeptides. Plays a role in male tail tip morphogenesis. In the C-terminal section; belongs to the peptidase M41 family. (782 aa) |
| | elo-8 | Elongation of very long chain fatty acids protein. (292 aa) |
| | Y47C4A.1 | Uncharacterized protein. (408 aa) |
| | laat-1 | Lysosomal amino acid transporter 1; Amino acid transporter that specifically mediates the pH- dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes. May play a role in the degradation of autophagic substrates in autolysosomes by regulating lysosome function ; Belongs to the laat-1 family. (311 aa) |
| | Y43F8C.7 | Uncharacterized protein. (236 aa) |
| | ppgn-1 | AAA domain-containing protein. (747 aa) |
| | coa-1 | Cytochrome Oxidase Assembly subunits. (138 aa) |
| | sms-3 | Putative phosphatidylcholine:ceramide cholinephosphotransferase 3; Bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Does not function strictly as a SM synthase (By similarity). (425 aa) |
| | hut-1 | Yeast Homolog UDP-Gal Transporter. (340 aa) |
| | Y102A11A.6 | Uncharacterized protein. (286 aa) |
| | W09G3.8 | Uncharacterized protein. (80 aa) |
| | W07E6.3 | Sphingomyelin synthase-related 2; Belongs to the sphingomyelin synthase family. (327 aa) |
| | immt-2 | MICOS complex subunit MIC60-2; Sustains mitochondrial morphology probably through maintaining cristae morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). (654 aa) |
| | ret-1 | Reticulon-like protein. (3303 aa) |
| | W04C9.2 | MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (102 aa) |
| | W02F12.2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid; Belongs to the alkaline ceramidase family. (272 aa) |
| | lem-2 | LEM protein 2; Essential protein involved in chromosome segregation and cell division, probably via its interaction with lmn-1, the main component of nuclear lamina. Has some overlapping function with emr-1. May play a role in radiation-induced DNA damage repair response. (500 aa) |
| | fat-6 | Delta(9)-fatty-acid desaturase fat-6; Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA and heptadecanyol-CoA. Belongs to the fatty acid desaturase type 1 family. (339 aa) |
| | samp-1 | Transmembrane protein 201 homolog; Plays a role in nuclear migration in hypodermal cells. Belongs to the TMEM201 family. (588 aa) |
| | T22C1.3 | PhosphatidylInositol Glycan anchor biosynthesis class T. (421 aa) |
| | unc-47 | Vesicular GABA transporter; Involved in the uptake of GABA into the synaptic vesicles. Belongs to the amino acid/polyamine transporter 2 family. (486 aa) |
| | hpo-8 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase hpo-8; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precu [...] (218 aa) |
| | immt-1 | MICOS complex subunit MIC60-1; Sustains mitochondrial morphology probably through maintaining cristae morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). (679 aa) |
| | hpo-5 | PhosphatidylInositol Glycan anchor biosynthesis class S. (550 aa) |
| | dop-3 | Dopamine receptor 3; Receptor for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. In terms of antagonist responses, would be classed with the D2-like dopamine receptor group. Mediates the effect of dopamine on the inhibition of locomotion. Acts as an antagonist of dop-1. (607 aa) |
| | T11G6.4 | MFS domain-containing protein. (499 aa) |
| | T11G6.3 | MFS domain-containing protein. (475 aa) |
| | T11G6.2 | MFS domain-containing protein. (502 aa) |
| | T10H10.2 | Sulfhydryl oxidase. (574 aa) |
| | T10C6.6 | MFS domain-containing protein. (465 aa) |
| | mom-1 | Protein-serine O-palmitoleoyltransferase porcupine; Key regulator of the Wnt signaling pathway that mediates lipid modification of Wnt proteins. Acts as a protein-serine O-palmitoleoyltransferase that catalyzes the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1), to Wnt proteins (By similarity). Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors (By similarity). Has a role in cell specification, specifically in blastomere signaling. Involved in cytosketetal polarity. Required for the orientation of mitotic spindle [...] (442 aa) |
| | vglu-3 | Potential vesicular glutamate transporter vglu-3. (544 aa) |
| | unc-50 | Protein unc-50; Required for cell surface expression of acetylcholine receptors in body-wall muscles. (301 aa) |
| | T06D8.9 | Uncharacterized protein. (316 aa) |
| | fndc-1 | FUN14 domain-containing protein fndc-1; Mitophagy receptor which plays a role in paternal mitochondria degradation in embryos after the two-cell stage. (138 aa) |
| | T05F1.8 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (393 aa) |
| | hpo-4 | Putative GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein (By similarity); Belongs to the peptidase C13 family. (319 aa) |
| | imp-2 | Intramembrane protease 2; Acts as intramembrane protease (Probable). In larvae, required for the complete shedding of the cuticle during molting, possibly by regulating cholesterol uptake via lrp-1. Involved in embryonic and larval development ; Belongs to the peptidase A22B family. (468 aa) |
| | sfxn-1.5 | Sidoreflexin. (324 aa) |
| | T03F1.12 | Protein SYS1 homolog; Involved in protein trafficking. Belongs to the SYS1 family. (148 aa) |
| | R151.6 | Derlin-2; May be required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Its precise function remains unclear, but its ability to complement der1 mutations in C.cerevisiae, suggests a similar function in the degradation of ER misfolded proteins. (237 aa) |
| | R10E4.9 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (202 aa) |
| | mpc-1 | Probable mitochondrial pyruvate carrier 1; May mediate the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (137 aa) |
| | mig-23 | Nucleoside-diphosphatase mig-23; Seems to be able to hydrolyze ADP, UDP and GDP. Supports mig- 17 glycosylation and surface expression, which is required for proper migration of distal tip cells during gonad morphogenesis. (552 aa) |
| | mig-14 | Protein wntless homolog; Probable sorting receptor which regulates endocytosis and secretion of the wnt ligand egl-20. Recycling of mig-14 from the plasma membrane to the Golgi apparatus by the retromer complex is essential for its function. Its endosomal trafficking is regulated by its association with sorting nexin snx-3 on early endosomes and the mtm-6/mtm-9 myotubularin complex. Required in embryonic development for endoderm specification and the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells. Functions during vulval development, [...] (549 aa) |
| | R01B10.6 | Uncharacterized protein. (274 aa) |
| | chch-3 | MICOS complex subunit MIC19; Plays a role in maintaining mitochondrial morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic19 subfamily. (169 aa) |
| | pst-1 | Adenosine 3'-phospho 5'-phosphosulfate transporter 1; Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi (By similarity). (440 aa) |
| | ymel-1 | ATP-dependent zinc metalloprotease YME1 homolog; ATP-dependent metalloprotease that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region (By similarity). Plays an important role in regulating mitochondrial morphology and function (By similarity); In the C-terminal section; belongs to the peptidase M41 family. (723 aa) |
| | srf-3 | UDP-galactose/UDP-N-acetylglucosamine transporter srf-3; Acts as a transporter of both UDP-galactose and UDP-N- acetylglucosamine into the Golgi lumen. (368 aa) |
| | emr-1 | Emerin homolog 1; Involved in chromosome segregation and cell division, probably via its interaction with lmn-1, the main component of nuclear lamina. Has some overlapping function with lem-2. May play a role in radiation- induced DNA damage repair response. (166 aa) |
| | K11H12.8 | Uncharacterized protein; Belongs to the BI1 family. (342 aa) |
| | vglu-2 | MFS domain-containing protein. (573 aa) |
| | K10B2.4 | Protein Asterix. (113 aa) |
| | erv-46 | Yeast ERV (ER to Golgi transport Vesicle protein) homolog. (380 aa) |
| | miro-1 | Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. (625 aa) |
| | nstp-7 | Nucleotide Sugar TransPorter family. (356 aa) |
| | bli-4 | Endoprotease bli-4; Serine endoprotease which cleaves proproteins at paired basic amino acids (Probable). Involved in cuticle biosynthesis probably by cleaving pro-collagen into its mature form. Acts in ASEL sensory neurons to regulate high salt chemotaxis responses probably by cleaving insulin-like protein ins-6 into its mature and active form. Essential for embryonic and larval development. isoform a, isoform e, isoform f, isoform g and isoform h are involved in cuticle biosynthesis but are dispensable for larval development. (942 aa) |
| | moma-1 | MICOS complex subunit MIC27; Sustains mitochondrial morphology probably through maintaining cristae morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). (201 aa) |
| | mcu-1 | Calcium uniporter protein, mitochondrial; Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore- forming and calcium-conducting subunit (By similarity). Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways (By similarity). Required for rapid mitochondrial calcium uptake and mitochondrial reactive oxygen species (mtROS) production after wounding. (333 aa) |
| | sec-12 | WD_REPEATS_REGION domain-containing protein. (425 aa) |
| | sms-1 | Phosphatidylcholine:ceramide cholinephosphotransferase 1; Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. (469 aa) |
| | emc-1 | EMC1_C domain-containing protein. (946 aa) |
| | coq-2 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. (370 aa) |
| | sun-1 | Sun domain-containing protein 1; Involved in centrosome attachment to the nucleus. Required for zyg-12 localization to the nuclear envelope. Together with pot-1, it is required to anchor telomeres to the nuclear envelope in embryos. (473 aa) |
| | yif-1 | YIP1-Interacting Factor homolog. (380 aa) |
| | elo-1 | Elongation of very long chain fatty acids protein. (288 aa) |
| | elo-7 | Elongation of very long chain fatty acids protein. (309 aa) |
| | marc-6 | RING-CH-type domain-containing protein. (1025 aa) |
| | pst-2 | Adenosine 3'-phospho 5'-phosphosulfate transporter 2; Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi (By similarity). (364 aa) |
| | unc-84 | Nuclear migration and anchoring protein unc-84; Involved in nuclear migration and anchoring in hypodermal precursor cells. Most likely recruits anc-1 to the nuclear envelope where anc-1 functions to tether the nucleus to the actin cytoskeleton. Component of the unc-83-unc-84 LINC (LInker of Nucleoskeleton and Cytoskeleton) complex where it recruits and interacts with unc-83 to form a bridge connecting the nuclear envelope to the cytoskeleton which allows for nuclear transport along microtubules. Its role in nuclear migration may be in association with lamin, lmn-1. Regulates nuclear mi [...] (1111 aa) |
| | F54A3.5 | MICOS complex subunit Mic10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (105 aa) |
| | sms-2 | Phosphatidylcholine:ceramide cholinephosphotransferase 2; Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. (335 aa) |
| | mpc-2 | Probable mitochondrial pyruvate carrier 2; May mediate the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (133 aa) |
| | F53B1.2 | Sphingomyelin synthase-related 1. (483 aa) |
| | fce-2 | CAAX prenyl protease 2 homolog; Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins; Belongs to the peptidase U48 family. (266 aa) |
| | F47B8.10 | MFS domain-containing protein. (456 aa) |
| | F47B7.2 | Sulfhydryl oxidase. (678 aa) |
| | rer-1 | Protein RER1 homolog; May be involved in protein transport along the secretory pathway; Belongs to the RER1 family. (191 aa) |
| | nstp-8 | Nucleotide Sugar TransPorter family. (351 aa) |
| | F44B9.5 | Ancient ubiquitous protein 1 homolog. (390 aa) |
| | fer-1 | Sperm vesicle fusion protein fer-1; Required for the fusion of the membranous organelles (MOs) with the plasma membrane, a process essential in spermiogenesis. (2034 aa) |
| | elo-6 | Elongation of very long chain fatty acids protein 6; Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs) and monomethyl branched-chain fatty acids (mmBCFAs). Required for the formation of isoheptadecanoate (C17iso). (274 aa) |
| | elo-5 | Elongation of very long chain fatty acids protein 5; Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs) and monomethyl branched-chain fatty acids (mmBCFAs). Required for the formation of isopentadecanoate (C15iso) and isoheptadecanoate (C17iso). Belongs to the ELO family. (274 aa) |
| | fis-1 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (143 aa) |
| | sfxn-1.2 | Sidoreflexin. (328 aa) |
| | F36D4.6 | Uncharacterized protein. (91 aa) |
| | F35G2.1 | Sulfhydryl oxidase. (601 aa) |
| | coa-3 | Coiled-coil_56 domain-containing protein. (133 aa) |
| | emc-6 | EMC Endoplasmic Membrane protein Complex (Yeast EMC) homolog. (111 aa) |
| | hpo-3 | GlycosylPhosphatidylinositol Anchor Attachment 1 homolog. (676 aa) |
| | F32D8.5 | Uncharacterized protein. (227 aa) |
| | F32B4.2 | Uncharacterized protein. (167 aa) |
| | aex-5 | Endoprotease aex-5; Probable serine endoprotease which cleaves preproteins at paired basic amino acids. May process FMRFamide-like (flp) and neuropeptide-like protein (nlp) neuropeptides. In muscles, involved in neuronal retrograde signaling by regulating presynaptic activity and localization of synaptic vesicle fusion protein unc-13 at the neuromuscular junction (NMJ). Acts in the intestine to regulate anterior body muscle contractions (aBOC) and the expulsion steps during the defecation motor program (DMP). Probably by regulating DMP, required for fatty acid uptake by intestinal cell [...] (537 aa) |
| | dpm-3 | Probable dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate-mannose synthase complex. (95 aa) |
| | F28C6.4 | PhosphatidylInositol Glycan anchor biosynthesis class G. (745 aa) |
| | F26F4.9 | Glutaredoxin domain-containing protein. (235 aa) |
| | F26F2.7 | Protein TAPT1 homolog. (714 aa) |
| | F25H2.4 | MPN domain-containing protein. (196 aa) |
| | cup-2 | Derlin-1; Specifically required for the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Belongs to the derlin family. (245 aa) |
| | tomm-20 | Mitochondrial import receptor subunit TOM20 homolog; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins (By similarity). Together with tomm-22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore. (188 aa) |
| | F22B5.10 | Calcium load-activated calcium channel homolog; Calcium-selective channel required to prevent calcium stores from overfilling. (186 aa) |
| | emre-1 | Essential MCU regulator, mitochondrial; Essential regulatory subunit of the mitochondrial calcium uniporter (mcu-1) channel, a protein that mediates calcium uptake into mitochondria; Belongs to the SMDT1/EMRE family. (90 aa) |
| | F17C11.7 | PhosphatidylInositol Glycan anchor biosynthesis class T. (531 aa) |
| | timm-23 | Translocase, Inner Mitochondrial Membrane. (242 aa) |
| | nstp-2 | Nucleotide Sugar TransPorter family. (324 aa) |
| | fis-2 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (151 aa) |
| | elo-2 | Elongation of very long chain fatty acids protein. (274 aa) |
| | kpc-1 | Furin-like protease kpc-1; Furin-like protease which cleaves proproteins at the RX(K/R)R consensus motif. During neuronal development, regulates the formation and extension of dendrite branches and cellular positioning of various type of neurons. Promotes the formation, extension and self-avoidance of dendritic branches of PVD and FLP mechanosensory neurons. In PVD neurons, regulates plasma membrane levels of branching receptor dma-1 by targeting it to late endosomes and thus promotes normal dendrite branching and dendrite self-avoidance. Also controls dendrite extension in AIY and D-t [...] (692 aa) |
| | prx-12 | Putative peroxisome assembly protein 12; Required for protein import into peroxisomes; Belongs to the pex2/pex10/pex12 family. (344 aa) |
| | F01G4.6 | Phosphate carrier protein, mitochondrial; Transport of phosphate groups from the cytosol to the mitochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. (387 aa) |
| | timm-17B.1 | Probable mitochondrial import inner membrane translocase subunit tim-17B.1; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane; Belongs to the Tim17/Tim22/Tim23 family. (181 aa) |
| | elo-3 | Putative fatty acid elongation protein 3; Could be implicated in synthesis of very long chain fatty acids (By similarity). May be required for normally rapid growth. Belongs to the ELO family. (320 aa) |
| | D2023.6 | ABC1 domain-containing protein. (512 aa) |
| | nstp-1 | Nucleotide Sugar TransPorter family. (318 aa) |
| | sfxn-1.4 | Sidoreflexin. (326 aa) |
| | prx-11 | PeRoXisome assembly factor. (214 aa) |
| | C42C1.19 | MFS domain-containing protein. (403 aa) |
| | ire-1 | Serine/threonine-protein kinase/endoribonuclease ire-1; Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices xbp-1 precursor mRNA to produce the mature form which then induces transcription of UPR target genes. Unfolded protein response (UPR) transcriptional activation by ire-1, as well as translational attenuation by pek-1 in a complementary pathway, maintains ER homeostasis. Regulates the transcriptional up-regulation of nucleoside-diphosphatase apy-1 upon ER str [...] (967 aa) |
| | sfxn-5 | Sideroflexin-5; Mitochondrial amino-acid transporter. Belongs to the sideroflexin family. (331 aa) |
| | elo-4 | Putative fatty acid elongation protein 4; Could be implicated in synthesis of very long chain fatty acids; Belongs to the ELO family. (291 aa) |
| | imp-1 | IntraMembrane Protease (IMPAS) family. (662 aa) |
| | C35D10.1 | ER membrane protein complex subunit 7 homolog. (222 aa) |
| | C34D4.4 | Uncharacterized Golgi apparatus membrane protein-like protein C34D4.4. (205 aa) |
| | C34B2.10 | Probable signal peptidase complex subunit 1; Microsomal signal peptidase is a membrane-bound endoproteinase that removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. (105 aa) |
| | imp-3 | IntraMembrane Protease (IMPAS) family. (530 aa) |
| | C33F10.12 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (392 aa) |
| | haf-1 | HAlF transporter (PGP related). (677 aa) |
| | C24G6.13 | Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Belongs to the COX16 family. (115 aa) |
| | tram-1 | Translocating chain-associated membrane protein; Belongs to the TRAM family. (373 aa) |
| | C18E9.2 | Uncharacterized protein. (364 aa) |
| | maa-1 | ACB domain-containing protein. (266 aa) |
| | prx-3 | PeRoXisome assembly factor. (353 aa) |
| | sfxn-2 | Sidoreflexin. (319 aa) |
| | C14C10.1 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (334 aa) |
| | catp-8 | Probable manganese-transporting ATPase catp-8; Mediates manganese transport into the endoplasmic reticulum. The ATPase activity is required for cellular manganese homeostasis. (1178 aa) |
| | lnp-1 | Endoplasmic reticulum junction formation protein lunapark-1; Plays a role in tubular endoplasmic reticulum network formation and maintenance (By similarity). May be involved in central nervous system development. Has a presynaptic role in neurotransmission. Likely to operate in synaptogenesis by regulating vesicular transport or localization. Required for correct localization of rab-3 and snb-1; Belongs to the lunapark family. (346 aa) |
| | let-721 | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; Accepts electrons from ETF and reduces ubiquinone. Belongs to the ETF-QO/FixC family. (597 aa) |
| | fce-1 | CAAX prenyl protease 1 homolog; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (442 aa) |
| | emc-5 | EMC Endoplasmic Membrane protein Complex (Yeast EMC) homolog. (144 aa) |
| | oxa-1 | OXA mitochondrial inner membrane insertase homolog. (366 aa) |
| | B0495.9 | Uncharacterized protein B0495.9. (267 aa) |
| | psd-1 | Phosphatidylserine decarboxylase proenzyme, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. (377 aa) |
| | B0334.5 | Uncharacterized protein. (420 aa) |
| | abu-1 | Activated in Blocked Unfolded protein response. (425 aa) |
| | sfxn-1.1 | Sideroflexin-1.1; Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. Belongs to the sideroflexin family. (329 aa) |
| | nstp-6 | Nucleotide Sugar TransPorter family. (383 aa) |
| | dhcr-7 | DeHydroCholesterol Reductase. (457 aa) |
