Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| F14D12.1 | unc-52 | F14D12.1b.1 | ZC101.2e.1 | Uncharacterized protein. | Basement membrane proteoglycan; Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Probable structural role in myofilament assembly and/or attachment of the myofilament lattice to the cell membrane. May be an extracellular anchor for integrin receptors in body wall muscles and myoepithelial sheath cells. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably downstream of the integrin complex formed by pat-2 and pat-3. Involved in ovulation. | 0.427 |
| Y57G11C.22 | ccb-2 | Y57G11C.22a.1 | W10C8.1a.1 | Uncharacterized protein. | SH3 domain-containing protein. | 0.552 |
| Y57G11C.22 | dyb-1 | Y57G11C.22a.1 | F47G6.1a.1 | Uncharacterized protein. | Dystrobrevin-1; Plays a role in cholinergic transmission and as a functional partner of dystrophin (dys-1), necessary for muscle maintenance. | 0.524 |
| abi-1 | mig-10 | B0336.6.2 | F10E9.6c.2 | SH3 domain-containing protein. | Abnormal cell migration protein 10; Required cell non-autonomously for proper development of the excretory canals and for the long-range anterior-posterior migrations of embryonic neurons CAN, ALM and HSN. Plays a role, probably downstream of ced-10/rac1, in orientating axonal growth of HSN and AVM neurons in response to guidance cues such as slt- 1. May regulate growth cone polarization by promoting asymmetric F-actin assembly. May be involved in signal transduction during cell migration. Belongs to the MRL family. | 0.950 |
| abi-1 | par-6 | B0336.6.2 | T26E3.3a.1 | SH3 domain-containing protein. | Partitioning defective protein 6; Necessary for apicobasal and anterior-posterior asymmetries associated with cell adhesion and gastrulation during the first few cell cycles of embryogenesis. Required for localizing/ maintaining par-3 at the cell periphery. Regulates mes-1 expression and/or localization pattern during early embryogenesis. Acts together with par-3 and pkc-3 in maintaining epithelial cell polarity in the distal spermatheca. Plays a role in endosome and Golgi body positioning. Belongs to the PAR6 family. | 0.402 |
| ajm-1 | dlg-1 | C25A11.4f.1 | C25F6.2a.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. | 0.992 |
| ajm-1 | jac-1 | C25A11.4f.1 | Y105C5B.21e.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Juxtamembrane domain-associated catenin; May act as a positive modulator of hmr-1 function during epidermal morphogenesis. Required for proper localization of other junctional components, such as pac-1 ; Belongs to the beta-catenin family. | 0.717 |
| ajm-1 | let-413 | C25A11.4f.1 | F26D11.11b.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Protein lap1; Critical role in assembling adherens junctions; adapter protein involved in polarizing protein trafficking in epithelial cells. Necessary to maintain, not establish, the entire terminal web (organelle-depleted, intermediate filament-rich layer of cytoplasm that underlies the apical microvilli of polarized epithelial cells) or brush border assembly at the apical surface gut cells. Required for correct localization of ifb-2 intermediate filaments in the terminal web. Required for dlg-1 lateral localization. With dlg-1, cooperatively regulates ajm-1 localization to apical ju [...] | 0.866 |
| ajm-1 | let-805 | C25A11.4f.1 | H19M22.2b.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Myotactin form B. | 0.586 |
| ajm-1 | lin-2 | C25A11.4f.1 | F17E5.1a.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Protein lin-2; May play a structural role in the induction of the vulva. May be required for the localization of signal transduction molecules (such as let-23 receptor) to either the basal membrane domain or the cell junctions. | 0.448 |
| ajm-1 | magu-2 | C25A11.4f.1 | C01B7.4a.2 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | MAGUK family; Belongs to the MAGUK family. | 0.571 |
| ajm-1 | par-6 | C25A11.4f.1 | T26E3.3a.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Partitioning defective protein 6; Necessary for apicobasal and anterior-posterior asymmetries associated with cell adhesion and gastrulation during the first few cell cycles of embryogenesis. Required for localizing/ maintaining par-3 at the cell periphery. Regulates mes-1 expression and/or localization pattern during early embryogenesis. Acts together with par-3 and pkc-3 in maintaining epithelial cell polarity in the distal spermatheca. Plays a role in endosome and Golgi body positioning. Belongs to the PAR6 family. | 0.660 |
| ajm-1 | unc-52 | C25A11.4f.1 | ZC101.2e.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | Basement membrane proteoglycan; Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Probable structural role in myofilament assembly and/or attachment of the myofilament lattice to the cell membrane. May be an extracellular anchor for integrin receptors in body wall muscles and myoepithelial sheath cells. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably downstream of the integrin complex formed by pat-2 and pat-3. Involved in ovulation. | 0.421 |
| ajm-1 | zoo-1 | C25A11.4f.1 | Y105E8A.26a.1 | Apical junction molecule; Controls adherens junction integrity. Required for the correct rate and completion of elongation of the embryos. | ZO-1 (Zonula Occludens tight junctional protein) Ortholog. | 0.628 |
| ccar-1 | egl-27 | Y37A1B.1a.1 | C04A2.3a.1 | SAP domain-containing protein. | Egg-laying defective protein 27; Transcription factor which promotes stress survival and delays aging. Required for cell cycle progression and development of the mesodermal and endodermal embryonic lineages. Required for normal T-cell polarity, for correct migration of QL neuroblast descendants and other cells, for embryonic patterning and for the embryonic expression of hlh-8. Also required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development. | 0.402 |
| ccar-1 | hrp-1 | Y37A1B.1a.1 | F42A6.7d.2 | SAP domain-containing protein. | Heterogeneous nuclear ribonucleoprotein A1; This protein is a component of ribonucleosomes. Overexpression gradually increases telomere length, leading to increase lifespan. | 0.459 |
| ccar-1 | mec-8 | Y37A1B.1a.1 | F46A9.6.3 | SAP domain-containing protein. | Mec-8 protein. | 0.669 |
| ccar-1 | unc-52 | Y37A1B.1a.1 | ZC101.2e.1 | SAP domain-containing protein. | Basement membrane proteoglycan; Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Probable structural role in myofilament assembly and/or attachment of the myofilament lattice to the cell membrane. May be an extracellular anchor for integrin receptors in body wall muscles and myoepithelial sheath cells. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably downstream of the integrin complex formed by pat-2 and pat-3. Involved in ovulation. | 0.661 |
| ccb-1 | ccb-2 | T28F2.5.1 | W10C8.1a.1 | GuKc domain-containing protein. | SH3 domain-containing protein. | 0.872 |
| ccb-1 | syd-2 | T28F2.5.1 | F59F5.6.1 | GuKc domain-containing protein. | Liprin-alpha; May play a role in regulating the structure of the neuronal region, called the active zone, from which synaptic vesicles send neurotransmitter signals across the synapse. This may be in association with the liprin-beta protein hlb-1 ; Belongs to the liprin family. Liprin-alpha subfamily. | 0.471 |
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