27 items (Caenorhabditis elegans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F08H9.3	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (147 aa)
	hsp-3	Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. (661 aa)
	hsp-43	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (393 aa)
	hsp-12.2	Heat shock protein Hsp-12.2; Belongs to the small heat shock protein (HSP20) family. (110 aa)
	hsp-70	Heat Shock Protein; Belongs to the heat shock protein 70 family. (643 aa)
	hsp-25	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (219 aa)
	ZK1128.7	SHSP domain-containing protein. (205 aa)
	Y55F3BR.6	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (253 aa)
	hsp-16.2	Heat shock protein Hsp-16.2; Belongs to the small heat shock protein (HSP20) family. (145 aa)
	hsp-16.41	Heat shock protein Hsp-16.41; Belongs to the small heat shock protein (HSP20) family. (143 aa)
	hsp-60	Chaperonin homolog Hsp-60, mitochondrial; Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (By similarity). (568 aa)
	hsp-16.1	Heat shock protein Hsp-16.1/Hsp-16.11. (145 aa)
	hsp-16.48	Heat shock protein Hsp-16.48/Hsp-16.49; Belongs to the small heat shock protein (HSP20) family. (143 aa)
	hsp-12.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (112 aa)
	dnj-19	DNaJ domain (Prokaryotic heat shock protein). (439 aa)
	stc-1	STCH (Truncated HSP) family. (450 aa)
	hsp-17	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (149 aa)
	F44E5.4	Uncharacterized protein; Belongs to the heat shock protein 70 family. (645 aa)
	hsp-4	Endoplasmic reticulum chaperone BiP homolog; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Required for ER dynamics during the first embryonic cell divisions. Specifically, controls ER transition into sheet-like structures at the onset of mitosis, possibly by regulating homotypic membrane fusion. Belongs to the heat shock protein 70 family. (657 aa)
	sip-1	Stress-induced protein 1; Belongs to the small heat shock protein (HSP20) family. (159 aa)
	dnj-12	DNaJ domain (Prokaryotic heat shock protein). (402 aa)
	hsp-12.6	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (110 aa)
	hsp-12.3	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (109 aa)
	hsp-1	Heat shock 70 kDa protein A. (640 aa)
	F11F1.1	DUF148 domain-containing protein; Belongs to the heat shock protein 70 family. (607 aa)
	F08H9.4	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (147 aa)
	hsp-6	Heat shock 70 kDa protein F, mitochondrial; Belongs to the heat shock protein 70 family. (657 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F08H9.3	F08H9.4	F08H9.3.1	F08H9.4a.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.473
F08H9.3	F11F1.1	F08H9.3.1	F11F1.1a.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	DUF148 domain-containing protein; Belongs to the heat shock protein 70 family.	0.459
F08H9.3	Y55F3BR.6	F08H9.3.1	Y55F3BR.6b.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.400
F08H9.3	ZK1128.7	F08H9.3.1	ZK1128.7.2	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein.	0.400
F08H9.3	hsp-1	F08H9.3.1	F26D10.3.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock 70 kDa protein A.	0.459
F08H9.3	hsp-12.1	F08H9.3.1	T22A3.2b.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.506
F08H9.3	hsp-12.2	F08H9.3.1	C14B9.1.2	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein Hsp-12.2; Belongs to the small heat shock protein (HSP20) family.	0.400
F08H9.3	hsp-12.3	F08H9.3.1	F38E11.1.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.512
F08H9.3	hsp-12.6	F08H9.3.1	F38E11.2.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.718
F08H9.3	hsp-16.2	F08H9.3.1	Y46H3A.3a.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein Hsp-16.2; Belongs to the small heat shock protein (HSP20) family.	0.400
F08H9.3	hsp-16.41	F08H9.3.1	Y46H3A.2.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein Hsp-16.41; Belongs to the small heat shock protein (HSP20) family.	0.423
F08H9.3	hsp-16.48	F08H9.3.1	T27E4.3.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein Hsp-16.48/Hsp-16.49; Belongs to the small heat shock protein (HSP20) family.	0.400
F08H9.3	hsp-17	F08H9.3.1	F52E1.7a.2	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.400
F08H9.3	hsp-25	F08H9.3.1	C09B8.6a.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.400
F08H9.3	hsp-43	F08H9.3.1	C14F11.5b.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.713
F08H9.3	sip-1	F08H9.3.1	F43D9.4.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	Stress-induced protein 1; Belongs to the small heat shock protein (HSP20) family.	0.400
F08H9.4	F08H9.3	F08H9.4a.1	F08H9.3.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.473
F08H9.4	F11F1.1	F08H9.4a.1	F11F1.1a.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	DUF148 domain-containing protein; Belongs to the heat shock protein 70 family.	0.461
F08H9.4	Y55F3BR.6	F08H9.4a.1	Y55F3BR.6b.1	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.400
F08H9.4	ZK1128.7	F08H9.4a.1	ZK1128.7.2	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	SHSP domain-containing protein.	0.400