STRINGSTRING
rpl-1 rpl-1 helq-1 helq-1 Y54H5A.1 Y54H5A.1 Y54E5B.2 Y54E5B.2 Y54E10BR.4 Y54E10BR.4 Y54E10A.10 Y54E10A.10 nsun-5 nsun-5 Y53C12B.1 Y53C12B.1 Y52B11A.10 Y52B11A.10 Y51H7C.7 Y51H7C.7 nol-6 nol-6 Y51H4A.15 Y51H4A.15 nol-14 nol-14 mac-1 mac-1 pinn-4 pinn-4 mrpl-20 mrpl-20 Y48B6A.1 Y48B6A.1 Y48A6B.3 Y48A6B.3 Y45F3A.9 Y45F3A.9 Y45F3A.8 Y45F3A.8 Y45F10D.7 Y45F10D.7 Y44F5A.1 Y44F5A.1 eef-1B.2 eef-1B.2 rps-28 rps-28 Y41C4A.9 Y41C4A.9 nsun-4 nsun-4 abce-1 abce-1 Y39B6A.33 Y39B6A.33 pro-3 pro-3 mrpl-22 mrpl-22 Y39A1A.14 Y39A1A.14 Y32H12A.8 Y32H12A.8 F58B3.4 F58B3.4 cri-3 cri-3 exos-3 exos-3 H06I04.3 H06I04.3 H20J04.4 H20J04.4 JC8.2 JC8.2 ran-1 ran-1 K01G5.5 K01G5.5 K05C4.5 K05C4.5 nol-56 nol-56 K07E8.7 K07E8.7 nol-9 nol-9 lpd-6 lpd-6 lin-23 lin-23 K10C3.5 K10C3.5 mrpl-36 mrpl-36 K12H4.3 K12H4.3 riok-1 riok-1 M01E5.2 M01E5.2 M02B7.2 M02B7.2 M28.5 M28.5 R02D3.8 R02D3.8 ddx-52 ddx-52 lpd-7 lpd-7 rpl-6 rpl-6 pro-1 pro-1 T01B7.5 T01B7.5 rps-16 rps-16 fib-1 fib-1 T02H6.1 T02H6.1 tfbm-1 tfbm-1 nifk-1 nifk-1 rps-5 rps-5 rps-19 rps-19 T05H4.10 T05H4.10 T06E6.1 T06E6.1 eri-1 eri-1 rbd-1 rbd-1 T25G3.3 T25G3.3 rrp-8 rrp-8 nog-1 nog-1 T10B5.3 T10B5.3 T20B12.3 T20B12.3 T22H9.1 T22H9.1 T23D8.3 T23D8.3 T26G10.1 T26G10.1 byn-1 byn-1 F57B10.8 F57B10.8 rps-27 rps-27 ddx-15 ddx-15 wdr-12 wdr-12 F55F8.3 F55F8.3 F55F10.1 F55F10.1 rpl-25.1 rpl-25.1 nath-10 nath-10 F54C9.9 F54C9.9 rpl-5 rpl-5 rpl-7 rpl-7 F53F4.11 F53F4.11 F53E10.6 F53E10.6 F52C12.2 F52C12.2 rpl-25.2 rpl-25.2 F45G2.9 F45G2.9 F44G4.1 F44G4.1 rps-8 rps-8 exos-8 exos-8 F39G3.3 F39G3.3 rps-14 rps-14 exos-9 exos-9 rps-21 rps-21 rps-15 rps-15 mrpl-1 mrpl-1 F33A8.4 F33A8.4 nol-10 nol-10 F32D8.4 F32D8.4 exos-7 exos-7 F30A10.9 F30A10.9 F29A7.6 F29A7.6 wdr-46 wdr-46 rpl-26 rpl-26 F27C1.6 F27C1.6 drsh-1 drsh-1 F25H8.2 F25H8.2 rla-0 rla-0 F25D7.5 F25D7.5 F19F10.9 F19F10.9 F18C12.3 F18C12.3 F13H8.2 F13H8.2 tag-151 tag-151 rpl-33 rpl-33 F10E7.5 F10E7.5 rpl-10 rpl-10 eral-1 eral-1 E02H1.1 E02H1.1 C53H9.2 C53H9.2 C50F4.12 C50F4.12 lpd-2 lpd-2 C48B6.2 C48B6.2 rrp-1 rrp-1 eif-6 eif-6 C43E11.9 C43E11.9 rpl-34 rpl-34 C38D4.9 C38D4.9 C34E10.10 C34E10.10 C27F2.4 C27F2.4 C26E6.12 C26E6.12 C25G4.3 C25G4.3 nola-3 nola-3 C18A3.3 C18A3.3 C16C10.8 C16C10.8 C16C10.2 C16C10.2 C16A3.6 C16A3.6 C16A3.4 C16A3.4 let-716 let-716 rrbs-1 rrbs-1 C15C6.4 C15C6.4 crn-3 crn-3 C10B5.1 C10B5.1 pro-2 pro-2 C06E1.9 C06E1.9 rha-2 rha-2 krr-1 krr-1 C04H5.1 C04H5.1 dis-3 dis-3 rpl-14 rpl-14 rpl-24.2 rpl-24.2 exos-4.1 exos-4.1 B0511.6 B0511.6 rps-0 rps-0 B0280.9 B0280.9 crn-4 crn-4 rpl-7A rpl-7A Y23H5B.6 Y23H5B.6 Y23H5B.5 Y23H5B.5 riok-2 riok-2 W09C5.1 W09C5.1 mtr-4 mtr-4 W07E6.2 W07E6.2 nol-2 nol-2 sbds-1 sbds-1 mrps-11 mrps-11 nol-58 nol-58 Y6B3B.9 Y6B3B.9 Y66H1A.4 Y66H1A.4 Y75B8A.7 Y75B8A.7 Y66A7A.2 Y66A7A.2 Y61A9LA.10 Y61A9LA.10 mrps-7 mrps-7 exos-2 exos-2 lsm-6 lsm-6 zhit-3 zhit-3 ZK795.3 ZK795.3 ZK792.5 ZK792.5 xpo-1 xpo-1 rpl-35 rpl-35 riok-3 riok-3 ZK546.14 ZK546.14 ZK470.1 ZK470.1 ZK430.7 ZK430.7 toe-1 toe-1 nol-16 nol-16 mett-10 mett-10 ZK1127.5 ZK1127.5 ncl-1 ncl-1 frg-1 frg-1 ZC434.4 ZC434.4 rps-7 rps-7 Y94H6A.5 Y94H6A.5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl-160S ribosomal protein L10a; Belongs to the universal ribosomal protein uL1 family. (216 aa)
helq-1Helicase C-terminal domain-containing protein. (923 aa)
Y54H5A.1WD_REPEATS_REGION domain-containing protein. (453 aa)
Y54E5B.2WD_REPEATS_REGION domain-containing protein. (861 aa)
Y54E10BR.4RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (364 aa)
Y54E10A.10Ribosome production factor 2 homolog. (297 aa)
nsun-5SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (439 aa)
Y53C12B.1WD_REPEATS_REGION domain-containing protein. (793 aa)
Y52B11A.10MI domain-containing protein. (819 aa)
Y51H7C.7Uncharacterized protein. (133 aa)
nol-6Nucleolar protein 6. (1058 aa)
Y51H4A.15Uncharacterized protein. (174 aa)
nol-14NucleOLar protein. (829 aa)
mac-1Protein mac-1; Probably together with ced-9, plays a modest role in preventing ced-4 and caspase ced-3-mediated apoptosis. Belongs to the AAA ATPase family. (813 aa)
pinn-4Peptidyl-prolyl cis-trans isomerase. (126 aa)
mrpl-20Mitochondrial Ribosomal Protein, Large. (191 aa)
Y48B6A.1Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (674 aa)
Y48A6B.3Putative H/ACA ribonucleoprotein complex subunit 2-like protein; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). (163 aa)
Y45F3A.9SpoU_sub_bind domain-containing protein. (294 aa)
Y45F3A.8Uncharacterized protein. (404 aa)
Y45F10D.7Uncharacterized protein. (924 aa)
Y44F5A.1WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (383 aa)
eef-1B.2Probable elongation factor 1-beta/1-delta 2; EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. (440 aa)
rps-2840S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family. (65 aa)
Y41C4A.9Uncharacterized protein. (577 aa)
nsun-4SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (465 aa)
abce-1ABC transporter, class E. (610 aa)
Y39B6A.33Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis, being required for integration of the 5S RNP into the ribosomal large subunit. (438 aa)
pro-3Protein SDA1 homolog; Required for 60S pre-ribosomal subunits export to the cytoplasm (Probable). Required for normal somatic gonad development and for regulation of germline development and proliferation. (801 aa)
mrpl-22Mitochondrial Ribosomal Protein, Large; Belongs to the universal ribosomal protein uL22 family. (260 aa)
Y39A1A.14Ribosomal RNA small subunit methyltransferase nep-1; S-adenosyl-L-methionine-dependent pseudouridine N(1)- methyltransferase that methylates a pseudouridine in 18S rRNA. Involved the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3- carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA. Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre- ribosomes; Belongs to the class IV-like SAM-binding methyltransferase superfami [...] (231 aa)
Y32H12A.8WD_REPEATS_REGION domain-containing protein. (3849 aa)
F58B3.4NUC153 domain-containing protein. (601 aa)
cri-3Conserved regulator of innate immunity protein 3; Belongs to the MAM33 family. (236 aa)
exos-3KH_dom_type_1 domain-containing protein. (226 aa)
H06I04.3Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (833 aa)
H20J04.4Uncharacterized protein; Belongs to the DEAD box helicase family. (561 aa)
JC8.2WD_REPEATS_REGION domain-containing protein. (467 aa)
ran-1GTP-binding nuclear protein ran-1; Ran GTPase system comprises ran-1, ran-2 and ran-3 and is essential in nucleocytoplasmic transport. Ran-1 is a GTP-binding protein that mediates the interaction between mitotic chromosomes and kinetochore microtubules. Plays a crucial role in nuclear envelope assembly at the end of each cell division. Required for the import of protein into the nucleus and also for RNA export. RCC1 (ran-3)/Ran (ran-1) complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. (215 aa)
K01G5.5Putative H/ACA ribonucleoprotein complex subunit 4; Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity); Belongs to the pseudouridine synthase TruB family. (445 aa)
K05C4.5Uncharacterized protein. (686 aa)
nol-56Nucleolar protein 56; Required for 60S ribosomal subunit synthesis. Belongs to the NOP5/NOP56 family. (486 aa)
K07E8.7Uncharacterized protein K07E8.7; Belongs to the pseudouridine synthase RluA family. (432 aa)
nol-9Polynucleotide 5'-hydroxyl-kinase nol-9; Polynucleotide 5'-kinase involved in rRNA processing. (549 aa)
lpd-6Brix domain-containing protein. (573 aa)
lin-23F-box/WD repeat-containing protein lin-23; Functions cell autonomously to negatively regulate cell cycle progression. Required to restrain cell proliferation in response to developmental cues. Probably recognizes and binds to some proteins and promotes their ubiquitination and degradation (By similarity). (667 aa)
K10C3.5Tr-type G domain-containing protein. (894 aa)
mrpl-36Ribosomal protein; Belongs to the bacterial ribosomal protein bL36 family. (77 aa)
K12H4.3Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. (352 aa)
riok-1Serine/threonine-protein kinase RIO1; Involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit (By similarity). Despite the protein kinase domain is proposed to act predominantly as an ATPase (By similarity). The catalytic activity regulates its dynamic association with the 40S subunit (By similarity). Plays a role in oogenesis by regulating germ cell proliferation, progression through diplotene and diakinesis stages and oocyte maturation. Regulates germline development probably by regulating the phosphorylation of mpk- 1. Involved in larval development. ECO:0 [...] (506 aa)
M01E5.2OBG-type G domain-containing protein. (358 aa)
M02B7.2Exonuclease domain-containing protein. (266 aa)
M28.5NHP2-like protein 1 homolog; Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding (By similarity); Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
R02D3.8Exonuclease domain-containing protein. (266 aa)
ddx-52DEAD boX helicase homolog. (581 aa)
lpd-7Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (531 aa)
rpl-660S ribosomal protein L6; Component of the large ribosomal subunit. Belongs to the eukaryotic ribosomal protein eL6 family. (217 aa)
pro-1Pre-rRNA-processing protein pro-1; Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (By similarity). Required for processing ITS2 sequences from rRNA intermediates during 26S rRNA maturation. Required in the soma to promote normal proliferation and prevent germline tumor formation. Belongs to the WD repeat IPI3/WDR18 family. (529 aa)
T01B7.5Sas10 domain-containing protein. (407 aa)
rps-1640S ribosomal protein S16. (144 aa)
fib-1rRNA 2'-O-methyltransferase fibrillarin; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins (By similarity). Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl- L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA (By similarity). Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (By similarity). Also acts as a protein [...] (352 aa)
T02H6.1WD_REPEATS_REGION domain-containing protein. (540 aa)
tfbm-1Dimethyladenosine transferase 1, mitochondrial; Probable S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA. Stimulates transcription independently of the methyltransferase activity (By similarity); Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily. (367 aa)
nifk-1RRM domain-containing protein. (307 aa)
rps-540S ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (210 aa)
rps-1940S ribosomal protein S19; Belongs to the eukaryotic ribosomal protein eS19 family. (146 aa)
T05H4.10NopRA1 domain-containing protein. (476 aa)
T06E6.1Uncharacterized protein. (431 aa)
eri-13'-5' exonuclease eri-1; RNA exonuclease that acts as a negative regulator of RNA interference (RNAi). Probably acts by degrading the 3'-overhangs of short interfering RNAs (siRNAs). Its tissue specificity may help explain the inefficiency of neuronal RNAi. (582 aa)
rbd-1RBD (RNA binding domain) protein. (872 aa)
T25G3.360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (513 aa)
rrp-8Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (343 aa)
nog-1Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit (By similarity). Has a role in regulating longevity, growth and brood size. May regulate fat storage via the insulin/IGF pathway. (681 aa)
T10B5.3Utp12 domain-containing protein. (295 aa)
T20B12.3Uncharacterized protein T20B12.3; Belongs to the CBF/MAK21 family. (504 aa)
T22H9.1Uncharacterized protein. (457 aa)
T23D8.3Protein LTV1 homolog; Belongs to the LTV1 family. (410 aa)
T26G10.1Putative ATP-dependent RNA helicase T26G10.1; Probable ATP-dependent RNA helicase which may be involved in ribosome biogenesis. (489 aa)
byn-1Uncharacterized protein byn-1; Belongs to the bystin family. (449 aa)
F57B10.8Uncharacterized protein. (268 aa)
rps-2740S ribosomal protein S27. (83 aa)
ddx-15Pre-mRNA-splicing factor ATP-dependent RNA helicase ddx-15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. (739 aa)
wdr-12Ribosome biogenesis protein WDR12 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat WDR12/YTM1 family. (439 aa)
F55F8.3Periodic tryptophan protein 2 homolog; Belongs to the WD repeat PWP2 family. (910 aa)
F55F10.1VWFA domain-containing protein. (4362 aa)
rpl-25.160S ribosomal protein L23a 1; This protein binds to a specific region on the 26S rRNA. (147 aa)
nath-10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1043 aa)
F54C9.9Kri1_C domain-containing protein. (740 aa)
rpl-560S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] (293 aa)
rpl-760S ribosomal protein L7; Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity). (244 aa)
F53F4.11Uncharacterized protein. (543 aa)
F53E10.6RRP15-like protein; Belongs to the RRP15 family. (191 aa)
F52C12.2Probable ribosome biogenesis protein CELE_F52C12.2; Probable pre-rRNA processing protein involved in ribosome biogenesis. (261 aa)
rpl-25.260S ribosomal protein L23a 2; This protein binds to a specific region on the 26S rRNA. (146 aa)
F45G2.9rRNA methyltransferase 2, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 808 (Um808) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA. (214 aa)
F44G4.1Brix domain-containing protein F44G4.1. (384 aa)
rps-840S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
exos-8RNase_PH domain-containing protein. (277 aa)
F39G3.3Uncharacterized protein. (714 aa)
rps-1440S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (152 aa)
exos-9EXOSome (Multiexonuclease complex) component. (434 aa)
rps-2140S ribosomal protein S21. (88 aa)
rps-1540S ribosomal protein S15; Negatively regulates lifespan. (151 aa)
mrpl-1Mitochondrial Ribosomal Protein, Large. (377 aa)
F33A8.4Uncharacterized protein. (467 aa)
nol-10NUC153 domain-containing protein. (754 aa)
F32D8.4PIH1 domain-containing protein. (291 aa)
exos-7RNase_PH domain-containing protein. (312 aa)
F30A10.9PINc domain-containing protein. (196 aa)
F29A7.6Protein F29A7.6; Belongs to the MPP6 family. (189 aa)
wdr-46WD_REPEATS_REGION domain-containing protein. (580 aa)
rpl-2660S ribosomal protein L26. (142 aa)
F27C1.6Uncharacterized protein. (647 aa)
drsh-1Ribonuclease 3; Executes the initial step of microRNA (miRNA) processing in the nucleus, that is the cleavage of pri-miRNA to release pre-miRNA. Involved in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in fertility. Required for the function or synthesis of the let-7 miRNA. Belongs to the ribonuclease III family. (1086 aa)
F25H8.2Uncharacterized protein. (390 aa)
rla-060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (312 aa)
F25D7.5EGF-like domain-containing protein. (1216 aa)
F19F10.9Uncharacterized protein. (829 aa)
F18C12.3Uncharacterized protein. (545 aa)
F13H8.2WD_REPEATS_REGION domain-containing protein. (929 aa)
tag-151Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus; Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily. (785 aa)
rpl-3360S ribosomal protein L35a; Belongs to the eukaryotic ribosomal protein eL33 family. (124 aa)
F10E7.5Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (220 aa)
rpl-1060S ribosomal protein L10. (214 aa)
eral-1Uncharacterized GTP-binding protein E02H1.2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. (394 aa)
E02H1.1Probable dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. (308 aa)
C53H9.2CP-type G domain-containing protein. (554 aa)
C50F4.12Uncharacterized protein. (439 aa)
lpd-2LiPid Depleted. (318 aa)
C48B6.2Putative 40S ribosomal protein S4-like. (183 aa)
rrp-1Ribosomal RNA processing protein 1 homolog; May be involved in the generation of 28S rRNA. Belongs to the RRP1 family. (397 aa)
eif-6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. Involved in miRNA-mediated gene silencing. (246 aa)
C43E11.960S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
rpl-34Ribosomal Protein, Large subunit. (110 aa)
C38D4.9MTS domain-containing protein. (214 aa)
C34E10.10Uncharacterized protein. (232 aa)
C27F2.4Uncharacterized protein. (283 aa)
C26E6.12OBG-type G domain-containing protein. (390 aa)
C25G4.3Uncharacterized protein. (227 aa)
nola-3Putative H/ACA ribonucleoprotein complex subunit 3; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). (64 aa)
C18A3.3Probable rRNA-processing protein EBP2 homolog; Required for the processing of the 27S pre-rRNA. (340 aa)
C16C10.8Uncharacterized protein C16C10.8. (253 aa)
C16C10.2Probable U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (262 aa)
C16A3.6Protein MAK16 homolog; Belongs to the MAK16 family. (323 aa)
C16A3.4C2H2-type domain-containing protein. (375 aa)
let-716Uncharacterized protein. (1743 aa)
rrbs-1Ribosome biogenesis regulatory protein homolog; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (333 aa)
C15C6.4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (198 aa)
crn-3HRDC domain-containing protein. (876 aa)
C10B5.1WD_REPEATS_REGION domain-containing protein. (311 aa)
pro-2Nucleolar complex protein 2 homolog; Required for normal somatic gonad development and for regulation of germline development and proliferation. (715 aa)
C06E1.9Uncharacterized protein C06E1.9. (643 aa)
rha-2Putative ATP-dependent RNA helicase rha-2; Probable ATP-binding RNA helicase; Belongs to the DEAD box helicase family. DEAH subfamily. (1148 aa)
krr-1KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (370 aa)
C04H5.1Multifunctional methyltransferase subunit TRM112-like protein; Acts as an activator of both RNA and protein methyltransferases. (125 aa)
dis-3Probable exosome complex exonuclease RRP44; Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. dis-3 has both 3'-5' exonuclease and endonuclease activities (By similarity). (961 aa)
rpl-14Ribosomal_L14e domain-containing protein. (135 aa)
rpl-24.2Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of NOG1 to pre-60S particles (By similarity). (162 aa)
exos-4.1Putative exosome complex component RRP41; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events; Belongs to the RNase PH family. (240 aa)
B0511.6RNA helicase. (544 aa)
rps-040S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. (276 aa)
B0280.9U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family. (429 aa)
crn-4Cell death-related nuclease 4; Involved in the degradation of chromosomal DNA. Contributes to cell killing. (298 aa)
rpl-7A60S ribosomal protein L7a; Belongs to the eukaryotic ribosomal protein eL8 family. (265 aa)
Y23H5B.6RNA helicase. (732 aa)
Y23H5B.5WD_REPEATS_REGION domain-containing protein. (561 aa)
riok-2Serine/threonine-protein kinase RIO2; Required for larval development. Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (529 aa)
W09C5.1Uncharacterized protein. (259 aa)
mtr-4mRNA transport homolog 4. (1026 aa)
W07E6.2WD_REPEATS_REGION domain-containing protein. (473 aa)
nol-2SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (664 aa)
sbds-1Ribosome maturation protein SBDS; Required for the assembly of mature ribosomes and ribosome biogenesis. Together with K10C3.5b/EFL1, triggers the GTP-dependent release of ribosome maturation factors from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation (By similarity). (253 aa)
mrps-11Mitochondrial Ribosomal Protein, Small. (208 aa)
nol-58Nop domain-containing protein. (487 aa)
Y6B3B.9Uncharacterized protein. (485 aa)
Y66H1A.4Probable H/ACA ribonucleoprotein complex subunit 1-like protein; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). (244 aa)
Y75B8A.7U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (648 aa)
Y66A7A.2Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (158 aa)
Y61A9LA.10Bms1-type G domain-containing protein. (1055 aa)
mrps-728S ribosomal protein S7, mitochondrial; Belongs to the universal ribosomal protein uS7 family. (222 aa)
exos-2EXOSome (Multiexonuclease complex) component. (303 aa)
lsm-6Sm domain-containing protein; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (77 aa)
zhit-3HIT-type domain-containing protein. (455 aa)
ZK795.3Brix domain-containing protein ZK795.3. (292 aa)
ZK792.5Uncharacterized protein. (645 aa)
xpo-1Importin N-terminal domain-containing protein. (1080 aa)
rpl-3560S ribosomal protein L35; Belongs to the universal ribosomal protein uL29 family. (123 aa)
riok-3Serine/threonine-protein kinase RIO3. (510 aa)
ZK546.14Uncharacterized protein ZK546.14. (472 aa)
ZK470.1Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (180 aa)
ZK430.7WD_REPEATS_REGION domain-containing protein. (444 aa)
toe-1HEAT repeat-containing protein 1 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in ribosome biosynthesis (By similarity); Belongs to the HEATR1/UTP10 family. (1650 aa)
nol-16Nucleolar protein 16. (189 aa)
mett-10U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that mediates N6-methylation of adenine of U6 small nuclear RNA (U6 snRNA) (By similarity). Involved in mRNA splicing (By similarity). Required for gamete production, inhibiting germ cell proliferative fate and ensuring germ cell meiotic development. Also promotes progression of the mitotic cell cycle in those germ cells that continue to proliferate. Plays a role in the development of the vulva, somatic gonad and embryo. Belongs to the methyltransferase superfamily. METTL16/RlmF family. (479 aa)
ZK1127.5Probable RNA 3'-terminal phosphate cyclase-like protein; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity); Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily. (379 aa)
ncl-1B-box type zinc finger protein ncl-1; Translational repressor that inhibits protein synthesis. Represses the translation of mRNAs such as fib-1, probably by being recruited by RNA-binding protein nos-2 and the Pumilio proteins puf-5, puf-8 and puf-9 to the consensus core PUF binding motif in the 3'-UTR of fib-1 mRNA. Negatively regulates ribosomal RNA (rRNA) synthesis, ribosomal protein synthesis and nucleolus size. Its role in the negative regulation of nucleolus size is most likely through its negative regulation of the translation of proteins such as the rRNA 2'- O-methyltransferase [...] (982 aa)
frg-1Protein FRG1 homolog; Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B (By similarity); Belongs to the FRG1 family. (274 aa)
ZC434.4Ribosomal RNA-processing protein 7 homolog; Belongs to the RRP7 family. (270 aa)
rps-740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
Y94H6A.5ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (825 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (16%) [HD]