Your Input: | |||||
stam-1 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. (457 aa) | ||||
vps-15 | Related to yeast Vacuolar Protein Sorting factor. (1354 aa) | ||||
vps-28 | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex, a regulator of vesicular trafficking process; Belongs to the VPS28 family. (210 aa) | ||||
Y74C10AL.2 | Uncharacterized protein. (157 aa) | ||||
vps-20 | Related to yeast Vacuolar Protein Sorting factor. (208 aa) | ||||
ego-2 | BRO1 domain-containing protein. (1494 aa) | ||||
vps-2 | Related to yeast Vacuolar Protein Sorting factor. (237 aa) | ||||
vps-25 | Related to yeast Vacuolar Protein Sorting factor. (183 aa) | ||||
vps-24 | Related to yeast Vacuolar Protein Sorting factor. (208 aa) | ||||
T24B8.2 | Charged Multivesicular Body Protein homolog. (411 aa) | ||||
T23G11.7 | Uncharacterized protein. (361 aa) | ||||
bec-1 | Beclin homolog; Regulates autophagy. Together with phosphatidyl-3-phosphate kinase vps-34, acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate (PtdIns3P), thereby regulating membrane trafficking. In association with sorf-1 and sorf-2, negatively regulates phosphatidylinositol 3- phosphate in early endosomes to allow for the conversion to late endosomes. Involved in the clearance of engulfed apoptotic cell corpses. Together with ced-9, negatively regulates somatic and germline apoptosis. Plays a role in endosome-to-Golgi retrograde tra [...] (375 aa) | ||||
R12C12.5 | Uncharacterized protein. (236 aa) | ||||
vps-60 | Related to yeast Vacuolar Protein Sorting factor. (217 aa) | ||||
did-2 | Doa4-Independent Degradation, homologous to yeast Did2. (205 aa) | ||||
vps-36 | GLUE N-terminal domain-containing protein. (383 aa) | ||||
vps-32.1 | Related to yeast Vacuolar Protein Sorting factor. (221 aa) | ||||
C30B5.2 | Vacuolar protein sorting-associated protein 55 homolog; Involved in endosomal protein transport. (132 aa) | ||||
vps-22 | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (269 aa) | ||||
C01A2.4 | Uncharacterized protein. (207 aa) |