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| | osm-9 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (937 aa) |
| | B0303.11 | Uncharacterized amino-acid permease B0303.11. (927 aa) |
| | B0310.1 | Uncharacterized protein B0310.1. (292 aa) |
| | twk-5 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (288 aa) |
| | eat-6 | Sodium/potassium-transporting ATPase subunit alpha. (996 aa) |
| | nhx-1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (514 aa) |
| | kcnl-1 | CaMBD domain-containing protein. (792 aa) |
| | nhx-2 | Na(+)/H(+) exchanger protein 2; Na(+)/H(+) antiporter that promotes normal di- or tripeptide transporter function, recovery following the peptide-induced acidification of the intestinal cytoplasm and maintenance of the peptide-dependent intestinal pH homeostasis. Regulator of free fatty acid uptake from the diet together with the dipeptide transporter pept- 1. May play a timekeeper role in defecation cycle but is not necessary for pbo-4-dependent proton release. May play a role in the regulation of lifespan independent of the stress response pathway. (644 aa) |
| | catp-4 | Sodium/potassium-transporting ATPase subunit alpha. (1015 aa) |
| | catp-2 | Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1050 aa) |
| | kcnl-3 | Small conductance calcium-activated potassium channel-like protein 3; Forms a voltage-independent potassium channel activated by intracellular calcium. (692 aa) |
| | zipt-2.1 | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. (363 aa) |
| | ncx-7 | Putative sodium/calcium exchanger 7. (672 aa) |
| | ncx-6 | Putative sodium/calcium exchanger 6. (590 aa) |
| | orai-1 | Protein orai; Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, stim-1. Required for Ca(2+) and IP3-dependent contractile activity of sheath cells and the spermatheca. Affects brood size and somatic cell function. Belongs to the Orai family. (297 aa) |
| | catp-3 | Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1054 aa) |
| | ncx-2 | Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (975 aa) |
| | del-8 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (553 aa) |
| | glt-1 | Excitatory amino acid transporter; Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium (By similarity). (503 aa) |
| | ncx-8 | Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (703 aa) |
| | ncx-9 | Mitochondrial sodium/calcium exchanger protein; Mitochondrial sodium/calcium antiporter that mediates sodium- dependent calcium efflux from mitochondrion, thereby acting as a key regulator of mitochondrion calcium homeostasis (Probable). Required for patterning of neural circuits: functions in the same pathway as RAC- dependent effectors of the unc-6/netrin signaling pathway to set left/ right patterning of the VD/DD GABAergic circuit. Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily. (701 aa) |
| | zipt-13 | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. (353 aa) |
| | cdf-1 | Cation diffusion facilitator family protein 1; Involved in the regulation of Pn.p cell fate determination. Involved in zinc metabolism and the decrease of the cytosolic zinc concentration which is thought to modulate Ras signaling. Involved in zinc transport from the intestinal lumen to the pseudocoelum. (561 aa) |
| | zipt-3 | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. (363 aa) |
| | del-9 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (579 aa) |
| | stg-1 | STarGazin (Mammalian calcium channel) homolog. (366 aa) |
| | twk-18 | TWiK family of potassium channels protein 18; Outwardly rectifying potassium channel protein; activity is sharply augmented by increase in temperature. Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (461 aa) |
| | delm-2 | DEgenerin Linked to Mechanosensation; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (608 aa) |
| | acd-1 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (635 aa) |
| | acd-2 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (693 aa) |
| | twk-39 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (676 aa) |
| | kqt-1 | Potassium channel, KvQLT family; Belongs to the potassium channel family. (740 aa) |
| | acd-3 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (484 aa) |
| | C27F2.6 | Uncharacterized protein. (165 aa) |
| | unc-103 | Potassium voltage-gated channel unc-103; Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly (By similarity). Regulates the movements of the male's copulatory spicules before and during male mating behavior ; Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily. (898 aa) |
| | zipt-17 | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. (386 aa) |
| | C32C4.1 | BTB domain-containing protein; Belongs to the potassium channel family. (575 aa) |
| | twk-26 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (519 aa) |
| | twk-20 | Two pore potassium channel protein sup-9. (364 aa) |
| | unc-105 | Degenerin-like protein unc-105; Ion channel which is permeable to small monovalent cations. Shown not to be H+-ion gated. May be mechanosensitive and is required for growth and muscle development; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (962 aa) |
| | clhm-1 | Calcium homeostasis modulator protein; Pore-forming subunit of a voltage-gated ion channel. Permeable to monovalent cations, divalent cations and anions with selectivity Ca(2+) > Mg(2+) > Na(+) = K(+) > Cl(-). Acts both as a voltage-gated and calcium-activated ion channel. Required for normal locomotion; Belongs to the CALHM family. (329 aa) |
| | twk-17 | Putative potassium channel subunit n2P17m2-2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (576 aa) |
| | del-7 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (614 aa) |
| | deg-1 | Degenerin deg-1; Probable sodium channel subunit. Required by a subset of neurons. (778 aa) |
| | egl-19 | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1877 aa) |
| | cho-1 | High-affinity choline transporter 1; Imports choline from the extracellular space to the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion and chloride ion dependent. (576 aa) |
| | twk-37 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (382 aa) |
| | unc-36 | Voltage-dependent calcium channel unc-36; May act as an auxiliary subunit of the unc-2 voltage-gated calcium channel which appears to trigger calcium-activated signaling pathways that control the serotonin response. Inhibiting serotonin sensitivity of the vulval muscles results in egg laying defects. May act in both neurons and muscle cells to enhance motor activity as it is required for coordinated movement. Has a role in neural depolarization- induced calcium influx and pharyngeal pumping. Involved in restricting the expression of the putative olfactory receptor str-2 to only one of [...] (1249 aa) |
| | twk-28 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (523 aa) |
| | kcnl-4 | CaMBD domain-containing protein. (485 aa) |
| | kvs-1 | Uncharacterized protein; Belongs to the potassium channel family. (495 aa) |
| | cca-1 | Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (1885 aa) |
| | nhx-3 | Probable Na(+)/H(+) antiporter nhx-3; Plays a role in epithelial membrane transport processes. (670 aa) |
| | del-1 | Degenerin del-1; Probable sodium channel subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (694 aa) |
| | flr-1 | FLR-1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (638 aa) |
| | kcnl-2 | CaMBD domain-containing protein. (855 aa) |
| | slo-2 | Ion_trans_2 domain-containing protein. (1143 aa) |
| | F10E7.9 | AA_permease domain-containing protein. (603 aa) |
| | exp-2 | Uncharacterized protein; Belongs to the potassium channel family. (510 aa) |
| | nhx-4 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (749 aa) |
| | mec-2 | Mechanosensory protein 2; Positively regulates the activity of the putative mechanosensory transduction channel. May link the mechanosensory channel and the microtubule cytoskeleton of the touch receptor neurons. Required for the function of a set of six touch receptor neurons. (1239 aa) |
| | shw-1 | BTB domain-containing protein; Belongs to the potassium channel family. (619 aa) |
| | egl-2 | Uncharacterized protein. (959 aa) |
| | mec-10 | Degenerin mec-10; Amiloride-sensitive sodium channel subunit required for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior. (724 aa) |
| | twk-6 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (347 aa) |
| | twk-23 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (443 aa) |
| | twk-11 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (1720 aa) |
| | F20D1.1 | Uncharacterized protein. (166 aa) |
| | twk-1 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (451 aa) |
| | F22B5.10 | Calcium load-activated calcium channel homolog; Calcium-selective channel required to prevent calcium stores from overfilling. (186 aa) |
| | twk-7 | TWiK family of potassium channels protein 7. (557 aa) |
| | delm-1 | DEgenerin Linked to Mechanosensation; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (626 aa) |
| | degt-1 | DEGenerin-related Touch-involved channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (852 aa) |
| | del-3 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (487 aa) |
| | F27C1.2 | Uncharacterized protein. (256 aa) |
| | slc-28.1 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (568 aa) |
| | slc-28.2 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (575 aa) |
| | acd-4 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (613 aa) |
| | ocr-1 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (850 aa) |
| | twk-12 | TWiK family of potassium channels protein 12. (684 aa) |
| | zipt-2.2 | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. (349 aa) |
| | zipt-1 | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. (318 aa) |
| | twk-35 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (557 aa) |
| | F31E8.4 | Uncharacterized protein. (162 aa) |
| | nac-1 | Sodium-dependent low-affinity dicarboxylate transporter 1; Low affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates. Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. (582 aa) |
| | twk-43 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (597 aa) |
| | twk-47 | Ion_trans_2 domain-containing protein. (500 aa) |
| | itr-1 | Inositol 1,4,5-trisphosphate receptor itr-1; Receptor for inositol 1,4,5-trisphosphate, a second messenger that regulates intracellular calcium homeostasis. Binds in vitro to both inositol 1,4,5-trisphosphate (1,4,5-InsP3) and inositol 2,4,5-trisphosphate (2,4,5-InsP3) with high affinity and does not discriminate between the phosphate at 1 or 2 position. Can also bind inositol 1,3,4,5-tetrakisphosphate (1,3,4,5-InsP4) and inositol 4,5-bisphosphate (4,5-InsP2), but with lower affinity. Acts as a timekeeper/rhythm generator via calcium signaling, affecting the defecation cycle and pharyn [...] (2892 aa) |
| | sup-9 | Two pore potassium channel protein sup-9; Potassium channel involved in coordination of muscle contraction. Activity is regulated by sup-18 ; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (329 aa) |
| | ncx-4 | Na_Ca_ex domain-containing protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (596 aa) |
| | twk-30 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (608 aa) |
| | kvs-3 | Uncharacterized protein; Belongs to the potassium channel family. (451 aa) |
| | twk-29 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (476 aa) |
| | abts-1 | Anion exchange protein. (1215 aa) |
| | twk-16 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (555 aa) |
| | twk-32 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (614 aa) |
| | twk-24 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (579 aa) |
| | zipt-2.4 | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. (468 aa) |
| | egas-4 | EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (883 aa) |
| | nhx-5 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (630 aa) |
| | nhx-6 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (634 aa) |
| | F58G6.3 | Uncharacterized protein. (134 aa) |
| | F58G6.7 | Uncharacterized protein. (166 aa) |
| | F58G6.8 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (198 aa) |
| | F58G6.9 | Uncharacterized protein. (156 aa) |
| | zipt-11 | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. (321 aa) |
| | del-5 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (526 aa) |
| | zipt-7.2 | Zinc transporter zipt-7.2; Zinc transporter. (462 aa) |
| | kcc-2 | K+/Cl-Cotransporter. (1129 aa) |
| | spe-41 | TRP homologous cation channel protein. (854 aa) |
| | twk-14 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (463 aa) |
| | kcc-3 | Potassium/chloride cotransporter 3; Probable potassium/chloride cotransporter that functions in the amphid sheath glial cells to regulate thermotaxis behavior. By maintaining chloride homeostasis, negatively regulates guanylate cyclase gcy-8 in the thermosensory AFD neurons and thereby controls the microvilli receptive ending morphology of the AFD neurons and thermotaxis. Modulates the temperature-evoked neuronal activity of the AFD neurons such as calcium responses to temperature gradients. Might also play a role in the chemotaxis behavior mediated by the sensory neurons AWA and AWC. (1081 aa) |
| | mcu-1 | Calcium uniporter protein, mitochondrial; Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore- forming and calcium-conducting subunit (By similarity). Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways (By similarity). Required for rapid mitochondrial calcium uptake and mitochondrial reactive oxygen species (mtROS) production after wounding. (333 aa) |
| | twk-10 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (429 aa) |
| | irk-3 | IRK_C domain-containing protein. (384 aa) |
| | twk-34 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (558 aa) |
| | nac-3 | Sodium-dependent high-affinity dicarboxylate transporter 3; High-affinity sodium-dicarboxylate cotransporter that accepts a range of tricarboxylic acid-cycle intermediates with 4-5 carbon atoms. There is no interaction with monocarboxylates. Plays a role in the regulation of life span. (566 aa) |
| | glt-3 | Putative sodium-dependent excitatory amino acid transporter glt-3. (532 aa) |
| | pbo-4 | Na(+)/H(+) exchanger protein 7; Na+/H+ exchanger which mediates the transient acidification of the coelomic space and plays a role in contraction of posterior body muscles during defecation. Probably by regulating the defecation motor program, required for fatty acid uptake by intestinal cells. (783 aa) |
| | unc-68 | Uncharacterized protein. (5202 aa) |
| | sca-1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1059 aa) |
| | smf-2 | NRAMP-like transporter smf-2; Probable divalent metal ion transporter which regulates Mn(2+) uptake. (546 aa) |
| | smf-1 | NRAMP-like transporter smf-1; Probable divalent metal ion transporter which regulates Mn(2+) uptake; Belongs to the NRAMP family. (562 aa) |
| | twk-48 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (372 aa) |
| | K12C11.3 | Uncharacterized protein. (147 aa) |
| | K12C11.6 | Uncharacterized protein. (132 aa) |
| | K12C11.7 | Uncharacterized protein. (166 aa) |
| | snf-6 | Sodium-dependent acetylcholine transporter; Mediates sodium-dependent uptake of acetylcholine at neuromuscular junctions during periods of increased synaptic activity, may also prevent spillover to adjacent synaptic sites. Not involved in the uptake of other neurotransmitters (GABA, glycine, proline and glutamate) and there was also no inhibition of uptake by adding an excess of other candidate substrates (GABA, glycine, taurine, creatine, proline, alanine, carnitine, glutamate and betaine). Required for muscle integrity; altered transport of acetylcholine due to loss of dystrophin-gly [...] (714 aa) |
| | irk-2 | Inward Rectifying K (Potassium) channel family. (497 aa) |
| | twk-25 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (683 aa) |
| | twk-3 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (383 aa) |
| | kqt-2 | Ion_trans domain-containing protein; Belongs to the potassium channel family. (695 aa) |
| | irk-1 | Inward rectifier potassium channel irk-1; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Required for modulation of the activity of the hermaphrodite-specific neurons (HSNs) by the G-protein coupled neuropeptide receptor egl-6 which in turn controls egg-laying behavior. (544 aa) |
| | twk-13 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (625 aa) |
| | mca-2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1158 aa) |
| | glt-6 | Putative sodium-dependent excitatory amino acid transporter glt-6. (542 aa) |
| | twk-49 | Ion_trans_2 domain-containing protein. (337 aa) |
| | trp-2 | TRP (Transient receptor potential) channel family; Belongs to the transient receptor (TC 1.A.4) family. (886 aa) |
| | egl-36 | Potassium voltage-gated channel protein egl-36; Voltage-dependent potassium channel involved in the excitation of muscles operating egg-laying and defecation. Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Shaw sub-subfamily. (558 aa) |
| | fpn-1.2 | Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (507 aa) |
| | twk-36 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (562 aa) |
| | kcc-1 | K+/Cl-Cotransporter. (1156 aa) |
| | unc-8 | Degenerin unc-8. (778 aa) |
| | cup-5 | PKD_channel domain-containing protein. (668 aa) |
| | shw-3 | BTB domain-containing protein; Belongs to the potassium channel family. (500 aa) |
| | twk-21 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (581 aa) |
| | twk-22 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (757 aa) |
| | mec-4 | Degenerin mec-4; Probable sodium channel subunit. May be needed for mechanosensory transduction (touch sensitivity). Negatively regulates the turning step of male mating behavior. (768 aa) |
| | zipt-9 | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. (381 aa) |
| | unc-2 | EF-hand domain-containing protein. (2171 aa) |
| | snf-11 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (610 aa) |
| | T04B8.5 | Uncharacterized protein. (952 aa) |
| | unc-58 | Uncoordinated protein 58; Has a role in mobility, possibly in the transport of potassium in muscles; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (591 aa) |
| | ocr-2 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (900 aa) |
| | ocr-3 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (818 aa) |
| | zipt-16 | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. (512 aa) |
| | twk-2 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (1519 aa) |
| | snf-3 | Sodium- and chloride-dependent betaine transporter; Betaine transporter dependent on Na(+) and Cl(-) ions that functions primarily in the epidermis to clear betaine from the extracellular space. Elicits current in response to betaine but not in response to GABA, L-carnitine, sarcosine, glycine or dimethylglycine. Belongs to the sodium:neurotransmitter symporter (SNF) family. (600 aa) |
| | tmc-1 | Transmembrane channel-like protein 1; Sodium-sensor ion channel that acts specifically in salt taste chemosensation. Required for salt-evoked neuronal activity and behavioral avoidance of high concentrations of NaCl. Belongs to the TMC family. (1285 aa) |
| | cdf-2 | Cation Diffusion Facilitator family. (360 aa) |
| | del-6 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (577 aa) |
| | glt-4 | Putative sodium-dependent excitatory amino acid transporter glt-4; Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D- aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport. (499 aa) |
| | dat-1 | Sodium-dependent dopamine transporter; Dopamine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. (615 aa) |
| | tag-180 | VWFA domain-containing protein. (1067 aa) |
| | twk-40 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (436 aa) |
| | del-4 | DEgenerin Like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (527 aa) |
| | del-10 | Degenerin-like protein del-10. (1069 aa) |
| | ccb-1 | GuKc domain-containing protein. (526 aa) |
| | acd-5 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (714 aa) |
| | zipt-7.1 | Zinc transporter zipt-7.1; Zinc transporter which regulates intracellular zinc levels. Required for spermatogenesis in both hermaphrodites and males where it resides in an inactive form in immature sperm, spermatids, but is likely activated in response to reduced spe-4 and spe-6 function. Upon activation, mediates the release of zinc from internal stores in spermatids into the cytoplasm. The resulting increase in cytoplasmic zinc levels promotes spermatid activation and subsequent differentiation into mature motile sperm that are capable of fertilization. (393 aa) |
| | asic-2 | Degenerin-like protein asic-2. (545 aa) |
| | cat-1 | MFS domain-containing protein. (553 aa) |
| | mfn-1 | Mitoferrin; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa) |
| | mec-6 | Mechanosensory abnormality protein 6; Probable touch-cell sodium channel subunit. May be needed for mechanosensory transduction (touch sensitivity). Interacts with degenerin channel proteins and stabilizes the channel. Non-voltage- gated amiloride-sensitive cation channel permeable for sodium, potassium, lithium and N-methylglucamine. Belongs to the paraoxonase family. (377 aa) |
| | glt-7 | Amino acid transporter. (541 aa) |
| | twk-42 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (444 aa) |
| | twk-33 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (617 aa) |
| | mca-1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1252 aa) |
| | hmt-1 | Heavy metal tolerance factor 1. (801 aa) |
| | ccb-2 | SH3 domain-containing protein. (396 aa) |
| | catp-1 | Cation_ATPase_N domain-containing protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1121 aa) |
| | Y105E8A.3 | SLC (SoLute Carrier) homolog. (746 aa) |
| | ncx-1 | Sodium-calcium exchanger; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (880 aa) |
| | nhx-8 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (681 aa) |
| | ncx-5 | Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (656 aa) |
| | egl-23 | Uncharacterized protein; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (726 aa) |
| | nkcc-1 | Na-K-Cl Cotransporter homolog. (1235 aa) |
| | fpn-1.1 | Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (509 aa) |
| | twk-46 | Two pore potassium channel protein sup-9. (319 aa) |
| | ttm-1 | Zinc transporter ttm-1; Promotes excretion of zinc from intestinal cells into the intestinal lumen in response to increased dietary zinc. Involved in cadmium resistance, possibly by promoting its transport from cells. Involved in resistance to B.thuringiensis pore-forming toxin Cry5B downstream of the sek-1 and pmk-1 MAPK kinase pathway. (410 aa) |
| | ocr-4 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (756 aa) |
| | twk-31 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (1136 aa) |
| | kvs-4 | Probable voltage-gated potassium channel subunit kvs-4; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. (512 aa) |
| | slo-1 | Calcium-activated potassium channel slo-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Essential for the regulation of neurotransmitter release at synapses. (1160 aa) |
| | glt-5 | Amino acid transporter. (491 aa) |
| | nipa-1 | NIPA1 (NonImprinted gene in Prader-Willi/Angelman syndrome region 1) homolog. (397 aa) |
| | mod-5 | Transporter. (671 aa) |
| | Y54F10AL.1 | GDT1 family protein. (297 aa) |
| | kqt-3 | Potassium channel, KvQLT family; Belongs to the potassium channel family. (621 aa) |
| | zipt-2.3 | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. (319 aa) |
| | stim-1 | Stromal interaction molecule 1; Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor which upon Ca(2+) depletion, activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, orai-1. Essential for Ca (2+) and IP3-dependent contractile activity of gonad sheath cells and spermatheca. Essential for fertility. Does not play a role in posterior body wall muscle contraction (pBoc) rhythmicity, intestinal cell oscillatory Ca(2+) signaling or intestinal ER Ca(2+) hemostasis. (530 aa) |
| | zipt-15 | Zrt (ZRT), Irt-(IRT-) like Protein Transporter. (413 aa) |
| | kvs-5 | Ion_trans domain-containing protein; Belongs to the potassium channel family. (600 aa) |
| | tric-1B.1 | Trimeric intracellular cation channel type 1B.1; Potassium channel that mediates transmembrane potassium transport. Might be required for maintenance of rapid intracellular calcium release (By similarity). May act as a counter-ion channel that functions in synchronization with calcium release from intracellular stores (By similarity). Binds phosphatidylinositol 4,5- bisphosphate (PIP2). (295 aa) |
| | tric-1B.2 | Trimeric intracellular cation channel type 1B.2; Potassium channel that mediates transmembrane potassium transport (By similarity). Might be required for maintenance of rapid intracellular calcium release (By similarity). May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores (By similarity). Binds phosphatidylinositol 4,5-bisphosphate (PIP2). (313 aa) |
| | Y57G11C.44 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (155 aa) |
| | Y58A7A.1 | Uncharacterized protein. (163 aa) |
| | mca-3 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1234 aa) |
| | smf-3 | NRAMP-like transporter smf-3; Probable divalent metal ion transporter which regulates the uptake of several heavy metals such as Mn(2+), Al(3+) and iron. Plays a role in modulating Al(3+)-induced dopamine (DA) neuron degeneration through the intracellular sequestration of Al(3+). (560 aa) |
| | egas-1 | EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (938 aa) |
| | egas-2 | EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (919 aa) |
| | egas-3 | EGF plus ASC domain ion channel; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (921 aa) |
| | trp-4 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (1924 aa) |
| | twk-45 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (508 aa) |
| | twk-44 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (733 aa) |
| | shl-1 | BTB domain-containing protein; Belongs to the potassium channel family. (578 aa) |
| | pkd-2 | Polycystin-2; Functions as a calcium permeable cation channel. Required for 2 aspects of male mating behavior: response to hermaphrodite contact and vulva location. Acts in the same pathway as lov-1 and atp-2 in response behavior. (716 aa) |
| | lron-12 | ELRR (Extracellular Leucine-Rich Repeat) ONly. (401 aa) |
| | cua-1 | Copper transporting ATPase. (1238 aa) |
| | ncx-10 | Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (668 aa) |
| | ncx-3 | Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (830 aa) |
| | trp-1 | Transient-receptor-potential-like protein; Could mediate calcium entry and form a calcium permeant channel; Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. (1047 aa) |
| | toc-1 | Similar to Transporter Of divalent Cations. (446 aa) |
| | twk-8 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (769 aa) |
| | tax-4 | Cyclic nucleotide-gated cation channel; Required for normal thermosensation and chemosensation sensory behavior. Required, downstream of receptor- type guanylate cyclase gcy-9, for CO2-mediated responses in BAG neurons. Required, downstream of receptor-type guanylate cyclase gcy-14, for alkaline pH-mediated responses in ASE-left (ASEL) neurons. Involved in the development of ASJ sensory neuron axon during late larval stages and in the maintenance of normal axon morphology in the adult. Regulates dauer formation. Required for the calcium flux to the cytoplasm in the ASJ sensory neurons [...] (733 aa) |
| | twk-4 | TWiK family of potassium channels; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (418 aa) |
| | twk-9 | TWiK family of potassium channels protein 9; Potassium channel protein that may be component of regulatory network that controls ray development and function. (568 aa) |
| | shk-1 | Potassium voltage-gated channel protein shk-1; Mediates the voltage-dependent potassium ion permeability of excitable membranes. Has an important role in repolarization and in regulating the pattern of action potential firing. Isoform a expresses currents in a more depolarized voltage range than isoform d. (536 aa) |
| | pmr-1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (978 aa) |
| | ced-11 | Protein ced-11; Plays a major role in programmed cell death. (1418 aa) |
| | eat-4 | Probable vesicular glutamate transporter eat-4; Required for glutamatergic synaptic transmission. In AWB and AWC sensory neurons, required for the detection of preferred food sources, probably via glutamatergic neurotransmission from sensory neurons. Negatively regulates the turning step of male mating behavior. (576 aa) |
| | ZK563.2 | Uncharacterized protein. (573 aa) |
| | asic-1 | Degenerin-like protein asic-1; Proton-gated cation channel; it is activated by a drop of the extracellular pH and then becomes rapidly desensitized. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Can also transport potassium ions, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions (By similarity). (823 aa) |
| | nhx-9 | Probable Na(+)/H(+) antiporter nhx-9; Serves some physiological function other than regulation of cellular pH. (667 aa) |
| | lov-1 | Location of vulva defective 1; Required for two aspects of male mating behavior: response to hermaphrodite contact and vulva location. Acts in the same pathway as pkd-2 and atp-2 in response behavior. May be required for ciliary targeting of pkd-2. (3284 aa) |
