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ced-10 | Ras-related protein ced-10; Required in engulfing to control the phagocytosis of apoptotic cell corpses. Required in embryonic development for the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells. Involved in hypodermal cell fusion, together with pak-1 and cdc-42, leading to embryonic body elongation, which involves dramatic cytoskeletal reorganization. ced-2 and ced-5 function to activate ced-10 in a GTPase signaling pathway that controls the polarized extension of cell surfaces. Plays a redundant role with mig-2 in dorsal axonal guid [...] (191 aa) | ||||
mig-2 | Rac-like GTPase. (195 aa) | ||||
enu-3.2 | ENhancer of Uncoordination. (462 aa) | ||||
unc-130 | Fork-head domain-containing protein. (333 aa) | ||||
pink-1 | Serine/threonine-protein kinase pink-1, mitochondrial; Protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins (By similarity). Plays a role in mitophagy. (641 aa) | ||||
enu-3.1 | ENhancer of Uncoordination. (204 aa) | ||||
enu-3.6 | ENhancer of Uncoordination. (319 aa) | ||||
rac-2 | Ras-related protein rac-2; During gonad morphogenesis, plays a role in distal tip cell (DTC)-mediated guidance of gonad elongation. (195 aa) | ||||
dgn-1 | Peptidase S72 domain-containing protein. (584 aa) | ||||
lrk-1 | Leucine-rich repeat serine/threonine-protein kinase 1; Determines polarized sorting of synaptic vesicle (SV) proteins to the axons by excluding SV proteins from the dendrite- specific transport machinery in the Golgi. Role in stress response. Appears to antagonize the effects of pink-1 both in the regulation of axon guidance and stress response; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily. (2393 aa) | ||||
enu-3.3 | ENhancer of Uncoordination. (462 aa) | ||||
enu-3.5 | ENhancer of Uncoordination. (458 aa) |