STRINGSTRING
stc-1 stc-1 dnj-26 dnj-26 tor-2 tor-2 tor-1 tor-1 Y22D7AL.10 Y22D7AL.10 hip-1 hip-1 bag-1 bag-1 dnj-13 dnj-13 F44E5.4 F44E5.4 hsp-4 hsp-4 hsp-1 hsp-1 F11F1.1 F11F1.1 hsp-6 hsp-6 ooc-5 ooc-5 hsp-3 hsp-3 hsp-70 hsp-70 dnj-1 dnj-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
stc-1STCH (Truncated HSP) family. (450 aa)
dnj-26J domain-containing protein. (365 aa)
tor-2Torsin. (310 aa)
tor-1Torsin. (310 aa)
Y22D7AL.10Uncharacterized protein; Belongs to the GroES chaperonin family. (108 aa)
hip-1TPR_REGION domain-containing protein. (422 aa)
bag-1BAG family molecular chaperone regulator 1; May inhibit the chaperone activity of HSP70/HSC70 by promoting substrate release in an ATP-dependent manner. (210 aa)
dnj-13J domain-containing protein. (331 aa)
F44E5.4Uncharacterized protein; Belongs to the heat shock protein 70 family. (645 aa)
hsp-4Endoplasmic reticulum chaperone BiP homolog; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Required for ER dynamics during the first embryonic cell divisions. Specifically, controls ER transition into sheet-like structures at the onset of mitosis, possibly by regulating homotypic membrane fusion. Belongs to the heat shock protein 70 family. (657 aa)
hsp-1Heat shock 70 kDa protein A. (640 aa)
F11F1.1DUF148 domain-containing protein; Belongs to the heat shock protein 70 family. (607 aa)
hsp-6Heat shock 70 kDa protein F, mitochondrial; Belongs to the heat shock protein 70 family. (657 aa)
ooc-5Torsin-like protein; May serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins; Belongs to the ClpA/ClpB family. Torsin subfamily. (356 aa)
hsp-3Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. (661 aa)
hsp-70Heat Shock Protein; Belongs to the heat shock protein 70 family. (643 aa)
dnj-1DnaJ homolog subfamily B member 1; Acts as a co-chaperone with Hsp70 required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity). Acts by determining Hsp70's ATPase and polypeptide-binding activities (By similarity). Can also act as a chaperone that promotes maturation of potassium channel unc-103 by stabilizing nascent channel subunits and assembling them into tetramers ; Belongs to the DnaJ family. DNAJB12/DNAJB14 subfamily. (401 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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