Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| W02A2.8 | him-10 | W02A2.8a.1 | R12B2.4.1 | Uncharacterized protein. | Kinetochore protein Nuf2 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules. Belongs to the NUF2 family. | 0.540 |
| W02A2.8 | ndc-80 | W02A2.8a.1 | W01B6.9.1 | Uncharacterized protein. | Kinetochore protein ndc-80; Acts as a component of the essential kinetochore-associated ndc-80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. Plays a role in kinetochore assembly and recruits the checkpoint protein mdf-2 and the spindly-like protein spdl-1 to unattached kinetochores. Mediates the formation of end-on kinetochore-microtubule attachments through recruitment of spdl-1. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolym [...] | 0.540 |
| csc-1 | icp-1 | Y48E1B.12.1 | Y39G10AR.13a.2 | Chromosome segregation and cytokinesis defective protein 1; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis during mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation. In the complex, it may be required to direct the Aurora B/air-2 to centromeric DNA; Belongs to the borealin family. Highly divergent. | INCENP_ARK-bind domain-containing protein. | 0.758 |
| csc-1 | ndc-80 | Y48E1B.12.1 | W01B6.9.1 | Chromosome segregation and cytokinesis defective protein 1; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis during mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation. In the complex, it may be required to direct the Aurora B/air-2 to centromeric DNA; Belongs to the borealin family. Highly divergent. | Kinetochore protein ndc-80; Acts as a component of the essential kinetochore-associated ndc-80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. Plays a role in kinetochore assembly and recruits the checkpoint protein mdf-2 and the spindly-like protein spdl-1 to unattached kinetochores. Mediates the formation of end-on kinetochore-microtubule attachments through recruitment of spdl-1. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolym [...] | 0.408 |
| csc-1 | smo-1 | Y48E1B.12.1 | K12C11.2.1 | Chromosome segregation and cytokinesis defective protein 1; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis during mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation. In the complex, it may be required to direct the Aurora B/air-2 to centromeric DNA; Belongs to the borealin family. Highly divergent. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.412 |
| gei-17 | smo-1 | W10D5.3c.3 | K12C11.2.1 | E3 SUMO-protein ligase gei-17; Functions as an E3-type smo-1 ligase. Mediates smo-1 conjugation to air-2 in vitro and is required for proper chromosome alignment. In the early embryo, specifically suppresses checkpoint activation in response to DNA damage, maybe by promoting mus-101 sumoylation. In embryos, plays a role in determining telomere localization in the nucleus. | Small ubiquitin-related modifier; Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex aos-1-uba-2 and linkage to the E2 enzyme ubc-9, and can be promoted by an E3 ligase such as gei-17. Required for embryonic dev [...] | 0.998 |
| hcp-4 | hcp-6 | T03F1.9.2 | Y110A7A.1b.1 | HoloCentric chromosome binding Protein. | Condensin-2 complex subunit. | 0.603 |
| hcp-4 | him-10 | T03F1.9.2 | R12B2.4.1 | HoloCentric chromosome binding Protein. | Kinetochore protein Nuf2 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules. Belongs to the NUF2 family. | 0.514 |
| hcp-4 | knl-1 | T03F1.9.2 | C02F5.1.1 | HoloCentric chromosome binding Protein. | Kinetochore null protein 1; Proposed to be part of the KMN network incorporating the MIS12 complex and NDC80 complex that is required for establishing the kinetochore-microtubule interface that aids in chromosome segregation during meiotic and mitotic cell division. Appears to function downstream of hcp-3 (CENP-A) and hcp-4 (CENP-C) in the kinetochore assembly hierarchy. Has a role in the correct localization of the spindly-like protein spdl-1 and the RZZ complex that is composed of rod-1, czw-1 and zwl-1 to kinetochores. Required for the recruitment of spindle-assembly checkpoint comp [...] | 0.640 |
| hcp-4 | ndc-80 | T03F1.9.2 | W01B6.9.1 | HoloCentric chromosome binding Protein. | Kinetochore protein ndc-80; Acts as a component of the essential kinetochore-associated ndc-80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. Plays a role in kinetochore assembly and recruits the checkpoint protein mdf-2 and the spindly-like protein spdl-1 to unattached kinetochores. Mediates the formation of end-on kinetochore-microtubule attachments through recruitment of spdl-1. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolym [...] | 0.763 |
| hcp-6 | hcp-4 | Y110A7A.1b.1 | T03F1.9.2 | Condensin-2 complex subunit. | HoloCentric chromosome binding Protein. | 0.603 |
| hcp-6 | him-10 | Y110A7A.1b.1 | R12B2.4.1 | Condensin-2 complex subunit. | Kinetochore protein Nuf2 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules. Belongs to the NUF2 family. | 0.594 |
| hcp-6 | icp-1 | Y110A7A.1b.1 | Y39G10AR.13a.2 | Condensin-2 complex subunit. | INCENP_ARK-bind domain-containing protein. | 0.534 |
| hcp-6 | knl-1 | Y110A7A.1b.1 | C02F5.1.1 | Condensin-2 complex subunit. | Kinetochore null protein 1; Proposed to be part of the KMN network incorporating the MIS12 complex and NDC80 complex that is required for establishing the kinetochore-microtubule interface that aids in chromosome segregation during meiotic and mitotic cell division. Appears to function downstream of hcp-3 (CENP-A) and hcp-4 (CENP-C) in the kinetochore assembly hierarchy. Has a role in the correct localization of the spindly-like protein spdl-1 and the RZZ complex that is composed of rod-1, czw-1 and zwl-1 to kinetochores. Required for the recruitment of spindle-assembly checkpoint comp [...] | 0.400 |
| hcp-6 | ndc-80 | Y110A7A.1b.1 | W01B6.9.1 | Condensin-2 complex subunit. | Kinetochore protein ndc-80; Acts as a component of the essential kinetochore-associated ndc-80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. Plays a role in kinetochore assembly and recruits the checkpoint protein mdf-2 and the spindly-like protein spdl-1 to unattached kinetochores. Mediates the formation of end-on kinetochore-microtubule attachments through recruitment of spdl-1. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolym [...] | 0.615 |
| hcp-6 | rmd-1 | Y110A7A.1b.1 | T05G5.7a.2 | Condensin-2 complex subunit. | Regulator of microtubule dynamics protein 1; Acts in chromosome segregation and organization during mitosis; Belongs to the FAM82/RMD family. | 0.548 |
| him-10 | W02A2.8 | R12B2.4.1 | W02A2.8a.1 | Kinetochore protein Nuf2 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules. Belongs to the NUF2 family. | Uncharacterized protein. | 0.540 |
| him-10 | hcp-4 | R12B2.4.1 | T03F1.9.2 | Kinetochore protein Nuf2 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules. Belongs to the NUF2 family. | HoloCentric chromosome binding Protein. | 0.514 |
| him-10 | hcp-6 | R12B2.4.1 | Y110A7A.1b.1 | Kinetochore protein Nuf2 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules. Belongs to the NUF2 family. | Condensin-2 complex subunit. | 0.594 |
| him-10 | icp-1 | R12B2.4.1 | Y39G10AR.13a.2 | Kinetochore protein Nuf2 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity. The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules. Belongs to the NUF2 family. | INCENP_ARK-bind domain-containing protein. | 0.650 |
page 1 of 3