node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
arf-6 | cnt-1 | Y116A8C.12.1 | Y17G7B.15a.1 | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. | Arf-GAP with ANK repeat and PH domain-containing protein cnt-1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Regulates endosome recycling downstream of rab-10 and upstream of arf-6. | 0.607 |
arf-6 | ehbp-1 | Y116A8C.12.1 | F25B3.1.1 | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. | EH (Eps-15-homology) domain Binding Protein family. | 0.762 |
arf-6 | rab-10 | Y116A8C.12.1 | T23H2.5.2 | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. | Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for basolateral endocytic recycling, the return of macromolecules and fluid from endosomes to the plasma membrane, in polarized epithelial cells of the intestine upstream of rm [...] | 0.459 |
arf-6 | rab-11.1 | Y116A8C.12.1 | F53G12.1.2 | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. | Ras-related protein rab-11.1; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Involved in regulating the meiotic maturation of oocytes. Plays a role in egg shell formation, regulating exocytosis of chondroitin proteoglycans following fertilization. Controls cor [...] | 0.649 |
arf-6 | rab-35 | Y116A8C.12.1 | Y47D3A.25.1 | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. | RAB family. | 0.936 |
arf-6 | rab-8 | Y116A8C.12.1 | D1037.4.2 | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. | RAB family. | 0.472 |
arf-6 | rfip-1 | Y116A8C.12.1 | F55C12.1b.1 | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. | FIP-RBD domain-containing protein. | 0.643 |
arf-6 | rme-1 | Y116A8C.12.1 | W06H8.1b.2 | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. | Receptor Mediated Endocytosis; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.886 |
arf-6 | sdpn-1 | Y116A8C.12.1 | F45E1.7b.1 | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. | SynDaPiN (Synaptic dynamin binding protein) homolog. | 0.750 |
chat-1 | rab-10 | R08C7.2a.2 | T23H2.5.2 | CDC50 family protein chat-1; Probable chaperone protein for the phospholipid-transporting ATPase tat-1. Regulates cell membrane structure and function. Plays a role in maintaining the membrane phosphatidylserine asymmetry and the formation of the tubular membrane structure. Involved in membrane trafficking and is specifically involved in the recycling and degradation of endocytic cargo and this is likely with the phospholipid-transporting ATPase tat-1. | Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for basolateral endocytic recycling, the return of macromolecules and fluid from endosomes to the plasma membrane, in polarized epithelial cells of the intestine upstream of rm [...] | 0.483 |
chat-1 | rab-11.1 | R08C7.2a.2 | F53G12.1.2 | CDC50 family protein chat-1; Probable chaperone protein for the phospholipid-transporting ATPase tat-1. Regulates cell membrane structure and function. Plays a role in maintaining the membrane phosphatidylserine asymmetry and the formation of the tubular membrane structure. Involved in membrane trafficking and is specifically involved in the recycling and degradation of endocytic cargo and this is likely with the phospholipid-transporting ATPase tat-1. | Ras-related protein rab-11.1; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Involved in regulating the meiotic maturation of oocytes. Plays a role in egg shell formation, regulating exocytosis of chondroitin proteoglycans following fertilization. Controls cor [...] | 0.558 |
chat-1 | rme-1 | R08C7.2a.2 | W06H8.1b.2 | CDC50 family protein chat-1; Probable chaperone protein for the phospholipid-transporting ATPase tat-1. Regulates cell membrane structure and function. Plays a role in maintaining the membrane phosphatidylserine asymmetry and the formation of the tubular membrane structure. Involved in membrane trafficking and is specifically involved in the recycling and degradation of endocytic cargo and this is likely with the phospholipid-transporting ATPase tat-1. | Receptor Mediated Endocytosis; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.637 |
chat-1 | tat-1 | R08C7.2a.2 | Y49E10.11c.1 | CDC50 family protein chat-1; Probable chaperone protein for the phospholipid-transporting ATPase tat-1. Regulates cell membrane structure and function. Plays a role in maintaining the membrane phosphatidylserine asymmetry and the formation of the tubular membrane structure. Involved in membrane trafficking and is specifically involved in the recycling and degradation of endocytic cargo and this is likely with the phospholipid-transporting ATPase tat-1. | Phospholipid-transporting ATPase tat-1; Transports phosphatidylserine from the outer to the inner leaflet of the plasma membrane, thereby maintaining the enrichment of this phospholipid in the inner leaflet. Ectopic exposure of phosphatidylserine on the cell surface may result in removal of living cells by neighboring phagocytes. Regulation of the phosphatidylserine distribution in plasma membranes is likely to help in the maintainence and control of the membrane surface charge. Plays a role in the formation of the tubular membrane structure and in membrane trafficking and is specifica [...] | 0.617 |
cnt-1 | arf-6 | Y17G7B.15a.1 | Y116A8C.12.1 | Arf-GAP with ANK repeat and PH domain-containing protein cnt-1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Regulates endosome recycling downstream of rab-10 and upstream of arf-6. | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. | 0.607 |
cnt-1 | rab-35 | Y17G7B.15a.1 | Y47D3A.25.1 | Arf-GAP with ANK repeat and PH domain-containing protein cnt-1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Regulates endosome recycling downstream of rab-10 and upstream of arf-6. | RAB family. | 0.953 |
cnt-1 | rab-8 | Y17G7B.15a.1 | D1037.4.2 | Arf-GAP with ANK repeat and PH domain-containing protein cnt-1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Regulates endosome recycling downstream of rab-10 and upstream of arf-6. | RAB family. | 0.482 |
cnt-1 | rfip-1 | Y17G7B.15a.1 | F55C12.1b.1 | Arf-GAP with ANK repeat and PH domain-containing protein cnt-1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Regulates endosome recycling downstream of rab-10 and upstream of arf-6. | FIP-RBD domain-containing protein. | 0.522 |
ehbp-1 | arf-6 | F25B3.1.1 | Y116A8C.12.1 | EH (Eps-15-homology) domain Binding Protein family. | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. | 0.762 |
ehbp-1 | rab-10 | F25B3.1.1 | T23H2.5.2 | EH (Eps-15-homology) domain Binding Protein family. | Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for basolateral endocytic recycling, the return of macromolecules and fluid from endosomes to the plasma membrane, in polarized epithelial cells of the intestine upstream of rm [...] | 0.972 |
ehbp-1 | rab-11.1 | F25B3.1.1 | F53G12.1.2 | EH (Eps-15-homology) domain Binding Protein family. | Ras-related protein rab-11.1; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Involved in regulating the meiotic maturation of oocytes. Plays a role in egg shell formation, regulating exocytosis of chondroitin proteoglycans following fertilization. Controls cor [...] | 0.513 |