STRINGSTRING
timp-1 timp-1 K07A1.6 K07A1.6 K05F1.10 K05F1.10 F53C11.9 F53C11.9 F47G3.4 F47G3.4 bli-5 bli-5 F44G3.7 F44G3.7 tag-196 tag-196 F36H9.4 F36H9.4 tag-290 tag-290 piit-1 piit-1 F32D8.7 F32D8.7 F32D8.3 F32D8.3 F30H5.3 F30H5.3 F22E12.1 F22E12.1 srp-7 srp-7 srp-8 srp-8 F15D3.4 F15D3.4 F13D2.1 F13D2.1 spon-1 spon-1 E01G6.1 E01G6.1 rpn-13 rpn-13 C54D10.10 C54D10.10 C53B7.2 C53B7.2 mec-9 mec-9 C49H3.16 C49H3.16 mig-6 mig-6 ced-4 ced-4 C34F6.1 C34F6.1 C28G1.2 C28G1.2 swm-1 swm-1 C25E10.8 C25E10.8 C25E10.7 C25E10.7 C25E10.10 C25E10.10 C10G8.4 C10G8.4 C10G8.3 C10G8.3 C10G8.2 C10G8.2 C09F9.2 C09F9.2 C08G9.2 C08G9.2 srp-1 srp-1 srp-2 srp-2 C04E6.12 C04E6.12 srp-6 srp-6 C02F12.5 C02F12.5 ubc-17 ubc-17 mlt-11 mlt-11 tep-1 tep-1 ZK287.4 ZK287.4 ZC84.6 ZC84.6 ZC84.1 ZC84.1 ZC504.1 ZC504.1 csp-2 csp-2 Y69H2.3 Y69H2.3 Y69H2.10 Y69H2.10 Y66D12A.9 Y66D12A.9 Y57G11C.5 Y57G11C.5 Y57E12AR.1 Y57E12AR.1 Y55F3BR.2 Y55F3BR.2 Y49G5A.1 Y49G5A.1 csp-3 csp-3 Y43F8B.3 Y43F8B.3 srp-3 srp-3 Y26D4A.12 Y26D4A.12 W05B2.2 W05B2.2 B0238.12 B0238.12 B0222.5 B0222.5 crm-1 crm-1 T22F7.3 T22F7.3 T21D12.7 T21D12.7 T21D12.12 T21D12.12 mec-1 mec-1 T06E6.10 T06E6.10 T01D3.6 T01D3.6 T01D3.3 T01D3.3 R12A1.3 R12A1.3 spi-1 spi-1 cpi-2 cpi-2 K12G11.6 K12G11.6 K11D12.7 K11D12.7 K11D12.6 K11D12.6 K11D12.13 K11D12.13 K11D12.11 K11D12.11 K10D3.4 K10D3.4 cpi-1 cpi-1 cri-2 cri-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
timp-1NTR domain-containing protein. (154 aa)
K07A1.6TIL domain-containing protein. (100 aa)
K05F1.10TIL domain-containing protein. (171 aa)
F53C11.9TIL domain-containing protein. (80 aa)
F47G3.4TIL domain-containing protein. (107 aa)
bli-5Kunitz-type protein bli-5; Appears to lack serine protease inhibitor activity in vitro when tested with bovine pancreatic alpha-chymotrypsin and elastase. Involved in cuticle biosynthesis. (202 aa)
F44G3.7Uncharacterized protein; Belongs to the serpin family. (705 aa)
tag-196Uncharacterized protein; Belongs to the peptidase C1 family. (477 aa)
F36H9.4TIL domain-containing protein. (78 aa)
tag-290Uncharacterized protein. (219 aa)
piit-1Protease Inhibitor I2 (Two). (200 aa)
F32D8.7BPTI/Kunitz inhibitor domain-containing protein. (380 aa)
F32D8.3TIL domain-containing protein. (245 aa)
F30H5.3Uncharacterized protein. (1599 aa)
F22E12.1Uncharacterized protein. (763 aa)
srp-7SERPIN domain-containing protein; Belongs to the serpin family. (373 aa)
srp-8SERPIN domain-containing protein; Belongs to the serpin family. (372 aa)
F15D3.4SERPIN domain-containing protein; Belongs to the serpin family. (823 aa)
F13D2.1A2M domain-containing protein. (1659 aa)
spon-1SPONdin (Extracellular matrix glycoprotein) family. (819 aa)
E01G6.1Uncharacterized protein. (1467 aa)
rpn-13Proteasomal ubiquitin receptor ADRM1 homolog; May function as a proteasomal ubiquitin receptor. May promote the deubiquitinating activity associated with the 26S proteasome. Belongs to the ADRM1 family. (406 aa)
C54D10.10Uncharacterized protein. (216 aa)
C53B7.2TIL domain-containing protein. (169 aa)
mec-9Uncharacterized protein. (838 aa)
C49H3.16BPTI/Kunitz inhibitor domain-containing protein. (206 aa)
mig-6Papilin; Involved in pharynx morphogenesis probably by remodeling the basement membrane. [Isoform b]: Plays a role in post embryonic distal cell tip migration. Essential extracellular matrix (ECM) protein required for hypodermal enclosure in the embryo. (2167 aa)
ced-4Cell death protein 4; Component of the egl-1, ced-9, ced-4 and ced-3 apoptotic signaling cascade required for the initiation of programmed cell death in cells fated to die during embryonic and postembryonic development. During oogenesis, required for germline apoptosis downstream of ced-9 and upstream of ced-3 but independently of egl-1. May regulate germline apoptosis in response to DNA damage, probably downstream of let-60/ras and mpk-1 pathway. Regulates CEP neuron apoptosis in response to high Al(3+) levels. During male tail morphogenesis, promotes apoptosis of the tail-spike cell [...] (571 aa)
C34F6.1Uncharacterized protein. (1043 aa)
C28G1.2SERPIN domain-containing protein; Belongs to the serpin family. (265 aa)
swm-1Serine protease inhibitor swm-1; Serine protease inhibitor (Probable). Probably by inhibiting serine protease tyr-5 in males, prevents the maturation of spermatids into mature motile spermatozoa until their transfer into a hermaphrodite. Also required for efficient sperm transfer and thus for male fertility. (135 aa)
C25E10.8Uncharacterized protein. (137 aa)
C25E10.7Uncharacterized protein. (157 aa)
C25E10.10TIL domain-containing protein. (169 aa)
C10G8.4TIL domain-containing protein. (98 aa)
C10G8.3BPTI/Kunitz inhibitor domain-containing protein. (190 aa)
C10G8.2BPTI/Kunitz inhibitor domain-containing protein. (208 aa)
C09F9.2Uncharacterized protein. (1642 aa)
C08G9.2Uncharacterized protein. (2224 aa)
srp-1Serine or cysteine protease inhibitor; Belongs to the serpin family. (366 aa)
srp-2SERPIN domain-containing protein; Belongs to the serpin family. (359 aa)
C04E6.12TIL domain-containing protein. (246 aa)
srp-6Serine or cysteine protease inhibitor. (375 aa)
C02F12.5BPTI/Kunitz inhibitor domain-containing protein C02F12.5. (176 aa)
ubc-17Probable ubiquitin-conjugating enzyme protein 17; Belongs to the ubiquitin-conjugating enzyme family. (728 aa)
mlt-11Uncharacterized protein. (3129 aa)
tep-1TEP (ThiolEster containing Protein). (1516 aa)
ZK287.4Uncharacterized protein. (1285 aa)
ZC84.6Uncharacterized protein. (1491 aa)
ZC84.1Uncharacterized protein ZC84.1. (1561 aa)
ZC504.1BPTI/Kunitz inhibitor domain-containing protein. (491 aa)
csp-2Putative inactive caspase B subunit p17; [Isoform b]: Putative inactive caspase. In the germline, binds caspase ced-3 zymogen and prevents ced-3 autoactivation. Does not affect the caspase activity of mature ced-3 and ced-4-mediated mature ced-3 activation. Negatively regulates germline apoptosis by inhibiting autocleavage of caspase ced-3. Involved in fertility ; Belongs to the peptidase C14A family. (826 aa)
Y69H2.3Uncharacterized protein. (796 aa)
Y69H2.10Uncharacterized protein. (572 aa)
Y66D12A.9Uncharacterized protein. (248 aa)
Y57G11C.5SERPIN domain-containing protein. (535 aa)
Y57E12AR.1BPTI/Kunitz inhibitor domain-containing protein. (99 aa)
Y55F3BR.2Uncharacterized protein. (1549 aa)
Y49G5A.1BPTI/Kunitz inhibitor domain-containing protein. (182 aa)
csp-3Non-catalytic caspase homolog csp-3; Non-catalytic caspase homolog which does not contain the region necessary for caspase activity. Acts as an inhibitor of caspase ced-3 zymogen autoactivation and delays ced-4- induced ced-3 processing. Has no effect on active ced-3. Probably by preventing ced-3 activation, protects cells, whose fate is to live, from apoptosis during embryonic and larval development ; Belongs to the peptidase C14A family. (139 aa)
Y43F8B.3Uncharacterized protein. (1658 aa)
srp-3Serine or cysteine protease inhibitor; Belongs to the serpin family. (362 aa)
Y26D4A.12TIL domain-containing protein. (76 aa)
W05B2.2Uncharacterized protein. (1278 aa)
B0238.12Uncharacterized protein. (166 aa)
B0222.5Uncharacterized protein. (369 aa)
crm-1CRiM (Cysteine Rich motor neuron protein) homolog. (966 aa)
T22F7.3Uncharacterized protein. (1074 aa)
T21D12.7Uncharacterized protein. (661 aa)
T21D12.12Uncharacterized protein. (183 aa)
mec-1Uncharacterized protein. (2007 aa)
T06E6.10TIL domain-containing protein. (249 aa)
T01D3.6Uncharacterized protein. (927 aa)
T01D3.3Thyroglobulin type-1 domain-containing protein. (1011 aa)
R12A1.3BPTI/Kunitz inhibitor domain-containing protein. (271 aa)
spi-1Serine protease inhibitor 1 protein. (100 aa)
cpi-2Cystatin cpi-2; Cysteine protease inhibitor which inhibits members of the peptidase C1 family. Does not inhibit asparaginyl endopeptidase. Required for the uptake and/or processing of yolk proteins during the development of oocytes, probably by regulating the catalytic activity of cysteine proteases cpl-1 and cpz-1. May play a protective role against exogenous cysteine proteases derived from soil bacteria or fungi, or rotting fruits and vegetation. Belongs to the cystatin family. (143 aa)
K12G11.6BPTI/Kunitz inhibitor domain-containing protein. (186 aa)
K11D12.7BPTI/Kunitz inhibitor domain-containing protein. (187 aa)
K11D12.6BPTI/Kunitz inhibitor domain-containing protein. (186 aa)
K11D12.13BPTI/Kunitz inhibitor domain-containing protein. (188 aa)
K11D12.11BPTI/Kunitz inhibitor domain-containing protein. (195 aa)
K10D3.4Uncharacterized protein. (922 aa)
cpi-1Cystatin cpi-1; Cysteine protease inhibitor which inhibits members of the peptidase C1 family. Does not inhibit asparaginyl endopeptidase. May play a protective role against exogenous cysteine proteases derived from soil bacteria or fungi, or rotting fruits and vegetation. Belongs to the cystatin family. (139 aa)
cri-2Putative metalloproteinase inhibitor tag-225; Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor. Belongs to the protease inhibitor I35 (TIMP) family. (158 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.