node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
K04F10.2 | ifta-2 | K04F10.2.1 | T28F3.6.1 | Protein KIAA0556 homolog; May regulate ciliary A-tubule number and, along with arl-13, controls cilium integrity. | Intraflagellar transport associated protein 2; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility. Regulates specific signaling activities in the cilia, such as the daf-2/insulin receptor-like transduction pathway. | 0.469 |
K04F10.2 | maph-9 | K04F10.2.1 | C34D4.1.1 | Protein KIAA0556 homolog; May regulate ciliary A-tubule number and, along with arl-13, controls cilium integrity. | Protein maph-9. | 0.828 |
K04F10.2 | nphp-4 | K04F10.2.1 | R13H4.1.1 | Protein KIAA0556 homolog; May regulate ciliary A-tubule number and, along with arl-13, controls cilium integrity. | NePHronoPhthisis (Human kidney disease) homolog. | 0.415 |
K04F10.2 | rpi-1 | K04F10.2.1 | W07G1.5b.1 | Protein KIAA0556 homolog; May regulate ciliary A-tubule number and, along with arl-13, controls cilium integrity. | Protein rpi-1. | 0.766 |
bbs-5 | bbs-8 | R01H10.6.1 | T25F10.5.1 | Bardet-Biedl syndrome 5 protein homolog; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for BBSome complex ciliary localization but not for the proper complex assembly (By similarity). Required, redundantly with bbs-4, for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins al [...] | Tetratricopeptide repeat protein 8; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for proper BBSome complex assembly and its ciliary localization. Required for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins along the ciliary axoneme. Plays a role in guanylyl cyclase loca [...] | 0.988 |
bbs-5 | dyf-13 | R01H10.6.1 | C27H5.7a.1 | Bardet-Biedl syndrome 5 protein homolog; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for BBSome complex ciliary localization but not for the proper complex assembly (By similarity). Required, redundantly with bbs-4, for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins al [...] | Intraflagellar transport protein 56 homolog; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility. | 0.581 |
bbs-5 | ifta-2 | R01H10.6.1 | T28F3.6.1 | Bardet-Biedl syndrome 5 protein homolog; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for BBSome complex ciliary localization but not for the proper complex assembly (By similarity). Required, redundantly with bbs-4, for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins al [...] | Intraflagellar transport associated protein 2; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. May be required for ciliary entrance and transport of specific ciliary cargo proteins such as che-3 which are related to motility. Regulates specific signaling activities in the cilia, such as the daf-2/insulin receptor-like transduction pathway. | 0.737 |
bbs-5 | nphp-1 | R01H10.6.1 | M28.7.1 | Bardet-Biedl syndrome 5 protein homolog; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for BBSome complex ciliary localization but not for the proper complex assembly (By similarity). Required, redundantly with bbs-4, for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins al [...] | Nephrocystin-1-like protein; May be necessary for initial assembly of the cilium. | 0.780 |
bbs-5 | nphp-4 | R01H10.6.1 | R13H4.1.1 | Bardet-Biedl syndrome 5 protein homolog; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for BBSome complex ciliary localization but not for the proper complex assembly (By similarity). Required, redundantly with bbs-4, for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins al [...] | NePHronoPhthisis (Human kidney disease) homolog. | 0.740 |
bbs-5 | osm-5 | R01H10.6.1 | Y41G9A.1.1 | Bardet-Biedl syndrome 5 protein homolog; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for BBSome complex ciliary localization but not for the proper complex assembly (By similarity). Required, redundantly with bbs-4, for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins al [...] | OSM-5. | 0.702 |
bbs-5 | rab-28 | R01H10.6.1 | Y11D7A.4.1 | Bardet-Biedl syndrome 5 protein homolog; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for BBSome complex ciliary localization but not for the proper complex assembly (By similarity). Required, redundantly with bbs-4, for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins al [...] | Ras-related protein Rab-28; GTPase. Intraflagellar transport (IFT) cargo that undergoes bidirectional IFT along the ciliary axoneme when in active GTP-bound state in amphid and phasmid ciliated sensory neurons. Targeting and function as IFT cargo may depend on the BBSome, an IFT cargo adapter. Does not undergo IFT when in inactive GDP-bound state. May in turn play a role in cilium structure and/or function in ciliated sensory neurons. Belongs to the small GTPase superfamily. Rab family. | 0.438 |
bbs-5 | xbx-1 | R01H10.6.1 | F02D8.3.1 | Bardet-Biedl syndrome 5 protein homolog; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for BBSome complex ciliary localization but not for the proper complex assembly (By similarity). Required, redundantly with bbs-4, for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins al [...] | X-BoX promoter element regulated. | 0.689 |
bbs-8 | bbs-5 | T25F10.5.1 | R01H10.6.1 | Tetratricopeptide repeat protein 8; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for proper BBSome complex assembly and its ciliary localization. Required for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins along the ciliary axoneme. Plays a role in guanylyl cyclase loca [...] | Bardet-Biedl syndrome 5 protein homolog; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for BBSome complex ciliary localization but not for the proper complex assembly (By similarity). Required, redundantly with bbs-4, for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins al [...] | 0.988 |
bbs-8 | osm-5 | T25F10.5.1 | Y41G9A.1.1 | Tetratricopeptide repeat protein 8; Component of the BBSome complex (By similarity). The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia (By similarity). The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function (By similarity). Required for proper BBSome complex assembly and its ciliary localization. Required for cilia biogenesis and both the assembly and movement of intraflagellar transport proteins along the ciliary axoneme. Plays a role in guanylyl cyclase loca [...] | OSM-5. | 0.516 |
ccdc-149 | cfap-36 | F29G6.2.1 | Y108G3AL.3a.1 | Coiled-coil domain-containing protein 149; Belongs to the CCDC149 family. | Cilia- and flagella-associated protein 36. | 0.610 |
ccdc-149 | famh-161 | F29G6.2.1 | Y38H6C.14.1 | Coiled-coil domain-containing protein 149; Belongs to the CCDC149 family. | Protein fam-161. | 0.696 |
ccdc-149 | maph-9 | F29G6.2.1 | C34D4.1.1 | Coiled-coil domain-containing protein 149; Belongs to the CCDC149 family. | Protein maph-9. | 0.605 |
ccdc-149 | rpi-1 | F29G6.2.1 | W07G1.5b.1 | Coiled-coil domain-containing protein 149; Belongs to the CCDC149 family. | Protein rpi-1. | 0.547 |
cfap-36 | ccdc-149 | Y108G3AL.3a.1 | F29G6.2.1 | Cilia- and flagella-associated protein 36. | Coiled-coil domain-containing protein 149; Belongs to the CCDC149 family. | 0.610 |
cfap-36 | famh-161 | Y108G3AL.3a.1 | Y38H6C.14.1 | Cilia- and flagella-associated protein 36. | Protein fam-161. | 0.821 |