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C10G8.2 | BPTI/Kunitz inhibitor domain-containing protein. (208 aa) | ||||
C10G8.3 | BPTI/Kunitz inhibitor domain-containing protein. (190 aa) | ||||
cle-1 | CoLlagen with Endostatin domain. (1175 aa) | ||||
mig-6 | Papilin; Involved in pharynx morphogenesis probably by remodeling the basement membrane. [Isoform b]: Plays a role in post embryonic distal cell tip migration. Essential extracellular matrix (ECM) protein required for hypodermal enclosure in the embryo. (2167 aa) | ||||
ost-1 | SPARC; Has a high affinity for collagen. Affects nematode body morphology and mobility. Essential for C.elegans development and muscle function. The cysteine-rich region could have protease inhibitory activity or may provide the framework for a protein binding module. Probable role in skeletal morphogenesis; Belongs to the SPARC family. (264 aa) | ||||
lam-2 | Laminin-like protein lam-2; During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably downstream of the integrin complex formed by pat-2 and pat-3. (1633 aa) | ||||
let-2 | Collagen alpha-2(IV) chain; Collagen type IV is specific for basement membranes (Probable). Together with fbl-1 and downstream of metalloprotease mig- 17, recruits nidogen nid-1 to the gonad basement membrane thereby probably inducing basement membrane remodeling required for the directional migration of distal tip cells. Required to restrict presynaptic growth at the neuromuscular junctions in late larval stage and in adult motor neurons. Vital for embryonic development. (1759 aa) | ||||
spon-1 | SPONdin (Extracellular matrix glycoprotein) family. (819 aa) | ||||
pals-1 | Protein containing ALS2cr12 (ALS2CR12) signature. (296 aa) | ||||
him-4 | EGF-like domain-containing protein. (5213 aa) | ||||
unc-6 | Netrin unc-6; Component of an extracellular matrix cue that guides dorsoventral migrations on the epidermis. Required for the guidance of pioneer axons and migrating cells along the body wall. During gonad morphogenesis, involved in distal tip cell (DTC) migration from the dorsal side of the hermaphrodite body to the midbody to allow for formation of gonad arms. Its association with either unc-40 or unc-5 receptors will lead to axon attraction or repulsion, respectively. Involved in the positioning of ray 1, the most anterior ray sensilium, in the male tail. Required for the formation [...] (612 aa) | ||||
col-173 | Col_cuticle_N domain-containing protein. (325 aa) | ||||
agr-1 | AGRin (Synaptic protein) homolog family member. (1473 aa) | ||||
elks-1 | Mammalian ELKS/CAST/ERC/Rab6 interacting protein homolog. (836 aa) | ||||
nid-1 | NIDogen (Basement membrane protein). (1584 aa) | ||||
fbl-1 | Fibulin-1; Incorporated into fibronectin-containing matrix fibers. Plays a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Important for certain developmental processes and contributes to the supramolecular organization of ECM architecture, in particular to those of basement membranes. [Isoform c]: Involved in the assembly of the flexible hemicentin-containing tracks found joining the pharynx and body-wall- muscle basement membranes; Belongs to the fibulin family. (751 aa) | ||||
mig-17 | Metalloprotease mig-17; Metalloprotease. Acts in the basement membrane to control directional migration of distal tip cells (DTCs) along the body wall basement membranes, a key step that promotes gonad morphogenesis. Regulates DTC migration probably by recruiting fibulin fbl-1, type IV collagen let-2 and nidogen nid-1 to the gonad basement membrane thereby promoting the remodeling of the basement membrane. During larval development and probably upstream of basement membrane proteins fbl-1, let-2 and nid-1, regulates pharynx length, probably by regulating pharyngeal cell length. Does no [...] (509 aa) | ||||
emb-9 | Collagen alpha-1(IV) chain; Collagen type IV is specific for basement membranes (Probable). Required to restrict presynaptic growth at the neuromuscular junctions (NMJ) in late larval stage and in adult motor neurons. May play a role in axon regeneration in embryos following injury in D-type motor neurons. (1759 aa) | ||||
pxn-2 | PeroXidasiN (Drosophila peroxidase) homolog. (1328 aa) | ||||
K11D12.11 | BPTI/Kunitz inhibitor domain-containing protein. (195 aa) | ||||
K11D12.6 | BPTI/Kunitz inhibitor domain-containing protein. (186 aa) | ||||
K11D12.7 | BPTI/Kunitz inhibitor domain-containing protein. (187 aa) | ||||
col-135 | COLlagen. (660 aa) | ||||
lam-3 | LAMinin related. See also lmb. (3102 aa) | ||||
lam-1 | LAMinin related. See also lmb. (1790 aa) | ||||
epi-1 | Laminin-like protein epi-1; During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably downstream of the integrin complex formed by pat-2 and pat-3. (3715 aa) | ||||
tln-1 | Talin. (2553 aa) | ||||
unc-52 | Basement membrane proteoglycan; Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Probable structural role in myofilament assembly and/or attachment of the myofilament lattice to the cell membrane. May be an extracellular anchor for integrin receptors in body wall muscles and myoepithelial sheath cells. During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles, probably downstream of the integrin complex formed by pat-2 and pat-3. Involved in ovulation. (3375 aa) | ||||
pat-3 | Integrin beta pat-3; Integrin alpha ina-1/beta pat-3 is a receptor for laminin. Integrin alpha pat-2/beta pat-3 recognizes the sequence R-G-D in its ligands (Probable). Plays a role in cell migration, morphogenesis and probably in cell-cell interactions. During gonad morphogenesis, involved in distal tip cell (DTC)-mediated guidance of gonad elongation, in maintaining their sharp tapering morphology and in their migration. Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Involved in the assembly of dense bodies and M line [...] (809 aa) | ||||
cdh-3 | Cadherin-3; Cell adhesion protein involved in the control of epithelial morphogenesis. Together with metalloproteinase zmp-1 and hemicentin him-4, plays a role in anchor cell (AC) invasion during postembryonic vulval development. (3361 aa) | ||||
pxn-1 | Peroxidasin homolog; Belongs to the peroxidase family. XPO subfamily. (1285 aa) | ||||
lect-2 | Peptidase_M23 domain-containing protein. (335 aa) |