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cus-2 cus-2 moa-2 moa-2 sap-49 sap-49 C50D2.5 C50D2.5 snr-4 snr-4 mog-2 mog-2 teg-4 teg-4 sftb-1 sftb-1 prp-21 prp-21 snr-2 snr-2 snr-1 snr-1 snr-6 snr-6 phf-5 phf-5 uaf-1 uaf-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cus-2Uncharacterized protein. (442 aa)
moa-2Protein moa-2. (87 aa)
sap-49Splicing factor 3B subunit 4; Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (By similarity). (388 aa)
C50D2.5Splicing factor 3B subunit 6-like protein; Necessary for the splicing of pre-mRNA. (138 aa)
snr-4Probable small nuclear ribonucleoprotein Sm D2; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity). (118 aa)
mog-2Probable U2 small nuclear ribonucleoprotein A; This protein is associated with sn-RNP U2. It helps the A' protein to bind stem loop IV of U2 snRNA. Required maternally for early embryonic development and zygotically for germline and somatic development. Has a role in the switch from mitosis to meiosis. Might function in alternative splicing. (253 aa)
teg-4CPSF_A domain-containing protein. (1220 aa)
sftb-1SF3b1 domain-containing protein. (1322 aa)
prp-21Yeast PRP (Splicing factor) related. (655 aa)
snr-2Probable small nuclear ribonucleoprotein-associated protein B; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure (By similarity); Belongs to the snRNP SmB/SmN family. (160 aa)
snr-1Small nuclear ribonucleoprotein Sm D3; Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity); Belongs to the snRNP core protein family. (136 aa)
snr-6Probable small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (90 aa)
phf-5PHd Finger family. (110 aa)
uaf-1Splicing factor U2AF 65 kDa subunit; Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns early during spliceosome assembly (By similarity). (496 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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