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sdha-1 sdha-1 lpd-5 lpd-5 ZK809.3 ZK809.3 Y63D3A.7 Y63D3A.7 nuo-3 nuo-3 nduf-5 nduf-5 Y53G8AL.2 Y53G8AL.2 Y51H1A.3 Y51H1A.3 nuo-5 nuo-5 cox-5A cox-5A nduf-7 nduf-7 cox-4 cox-4 nuo-6 nuo-6 ucr-2.1 ucr-2.1 T27E9.2 T27E9.2 nduf-2.2 nduf-2.2 ucr-2.3 ucr-2.3 T20H4.5 T20H4.5 nuo-2 nuo-2 ucr-2.2 ucr-2.2 mev-1 mev-1 T02H6.11 T02H6.11 R07E4.3 R07E4.3 ndfl-4 ndfl-4 nduo-5 nduo-5 nduo-3 nduo-3 ctc-1 ctc-1 nduo-4 nduo-4 ctb-1 ctb-1 nduo-2 nduo-2 nduo-1 nduo-1 gas-1 gas-1 cox-6A cox-6A F53F4.10 F53F4.10 F45H10.3 F45H10.3 F45H10.2 F45H10.2 F44G4.2 F44G4.2 F44E7.9 F44E7.9 isp-1 isp-1 F42G8.10 F42G8.10 sdhb-1 sdhb-1 F42A8.1 F42A8.1 sdhd-1 sdhd-1 F31D4.9 F31D4.9 cox-5B cox-5B sod-2 sod-2 cyc-1 cyc-1 C34B2.8 C34B2.8 sdha-2 sdha-2 C33A12.1 C33A12.1 C25H3.9 C25H3.9 C14B9.10 C14B9.10 nuo-1 nuo-1 sod-3 sod-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sdha-1Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (646 aa)
lpd-5LiPid Depleted. (176 aa)
ZK809.3Uncharacterized protein. (210 aa)
Y63D3A.7L51_S25_CI-B8 domain-containing protein. (92 aa)
nuo-3NADH Ubiquinone Oxidoreductase. (131 aa)
nduf-5NADH Ubiquinone oxidoreductase Fe-S protein. (121 aa)
Y53G8AL.2NAD(P)-bd_dom domain-containing protein. (431 aa)
Y51H1A.3Uncharacterized protein. (215 aa)
nuo-5NADH Ubiquinone Oxidoreductase; Belongs to the complex I 75 kDa subunit family. (729 aa)
cox-5ACytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (174 aa)
nduf-7Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (199 aa)
cox-4Cytochrome OXidase assembly protein. (175 aa)
nuo-6NADH Ubiquinone Oxidoreductase. (172 aa)
ucr-2.1Ubiquinol-Cytochrome c oxidoReductase complex. (424 aa)
T27E9.2Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (75 aa)
nduf-2.2Complex1_49kDa domain-containing protein; Belongs to the complex I 49 kDa subunit family. (474 aa)
ucr-2.3Peptidase_M16 domain-containing protein. (427 aa)
T20H4.5Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (212 aa)
nuo-2Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family. (268 aa)
ucr-2.2Ubiquinol-Cytochrome c oxidoReductase complex. (422 aa)
mev-1Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). Mediates resistance to enteropathogenic E.coli infection. Belongs to the cytochrome b560 family. (182 aa)
T02H6.11Uncharacterized protein. (130 aa)
R07E4.3Uncharacterized protein. (90 aa)
ndfl-4NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (77 aa)
nduo-5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (527 aa)
nduo-3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (111 aa)
ctc-1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (525 aa)
nduo-4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (409 aa)
ctb-1Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c (By similarity). Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (370 aa)
nduo-2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (282 aa)
nduo-1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (291 aa)
gas-1Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (482 aa)
cox-6ACytochrome c oxidase subunit 6A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (128 aa)
F53F4.10Probable NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (239 aa)
F45H10.3Uncharacterized protein. (168 aa)
F45H10.2Uncharacterized protein. (90 aa)
F44G4.2Probable NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (160 aa)
F44E7.9Uncharacterized protein. (121 aa)
isp-1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (276 aa)
F42G8.10Uncharacterized protein. (181 aa)
sdhb-1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (298 aa)
F42A8.1Uncharacterized protein F42A8.1. (370 aa)
sdhd-1Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (145 aa)
F31D4.9Uncharacterized protein. (70 aa)
cox-5BCytochrome OXidase assembly protein. (132 aa)
sod-2Superoxide dismutase [Mn] 1, mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. (221 aa)
cyc-1Cytochrome c domain-containing protein. (285 aa)
C34B2.8Uncharacterized protein. (171 aa)
sdha-2Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (640 aa)
C33A12.1Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (150 aa)
C25H3.9Uncharacterized protein. (186 aa)
C14B9.10Uncharacterized protein. (60 aa)
nuo-1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (479 aa)
sod-3Superoxide dismutase [Mn] 2, mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. (218 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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