37 items (Caenorhabditis elegans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C39B5.14	Lipase_3 domain-containing protein. (329 aa)
	C40H1.2	Uncharacterized protein C40H1.2. (208 aa)
	C40H1.8	Lipase_3 domain-containing protein. (342 aa)
	C40H1.9	Lipase_3 domain-containing protein. (349 aa)
	D2045.2	Uncharacterized protein. (1810 aa)
	did-2	Doa4-Independent Degradation, homologous to yeast Did2. (205 aa)
	F25A2.1	Lipase_3 domain-containing protein. (290 aa)
	F28H7.3	Lipase_3 domain-containing protein. (294 aa)
	vha-5	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (873 aa)
	vps-60	Related to yeast Vacuolar Protein Sorting factor. (217 aa)
	F46G10.4	Lipase_3 domain-containing protein. (336 aa)
	H04D03.3	Uncharacterized protein. (409 aa)
	H41C03.2	Lipase_3 domain-containing protein. (356 aa)
	K03H6.2	Lipase_3 domain-containing protein. (339 aa)
	K08B12.1	Lipase_3 domain-containing protein. (374 aa)
	alx-1	Apoptosis-linked gene 2-interacting protein X 1; Required for lin-12 degradation after it has been internalised in the vulval precursor cells. (882 aa)
	R12C12.5	Uncharacterized protein. (236 aa)
	R12C12.6	Uncharacterized protein. (261 aa)
	T08B1.4	Lipase_3 domain-containing protein. (342 aa)
	T21H3.1	Lipase_3 domain-containing protein. (305 aa)
	T23G11.7	Uncharacterized protein. (361 aa)
	T24B8.2	Charged Multivesicular Body Protein homolog. (411 aa)
	vps-24	Related to yeast Vacuolar Protein Sorting factor. (208 aa)
	Y110A7A.7	Lipase_3 domain-containing protein. (312 aa)
	vps-2	Related to yeast Vacuolar Protein Sorting factor. (237 aa)
	Y49E10.16	Lipase_3 domain-containing protein. (327 aa)
	Y49E10.18	Lipase_3 domain-containing protein. (335 aa)
	Y51A2B.4	Lipase_3 domain-containing protein. (345 aa)
	Y51H4A.5	Lipase_3 domain-containing protein. (329 aa)
	Y54G2A.45	Lipase_3 domain-containing protein. (337 aa)
	vps-20	Related to yeast Vacuolar Protein Sorting factor. (208 aa)
	ZK262.2	Lipase_3 domain-containing protein. (353 aa)
	ZK262.3	Lipase ZK262.3; Probable lipase; Belongs to the AB hydrolase superfamily. Lipase family. (353 aa)
	stam-1	Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. (457 aa)
	C14E2.6	Lipase_3 domain-containing protein. (194 aa)
	C01A2.4	Uncharacterized protein. (207 aa)
	B0035.13	Lipase_3 domain-containing protein. (297 aa)

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0035.13	F28H7.3	B0035.13.2	F28H7.3.1	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.552
C01A2.4	R12C12.5	C01A2.4.1	R12C12.5.1	Uncharacterized protein.	Uncharacterized protein.	0.808
C01A2.4	T24B8.2	C01A2.4.1	T24B8.2.1	Uncharacterized protein.	Charged Multivesicular Body Protein homolog.	0.717
C01A2.4	did-2	C01A2.4.1	F23C8.6.1	Uncharacterized protein.	Doa4-Independent Degradation, homologous to yeast Did2.	0.968
C01A2.4	stam-1	C01A2.4.1	C34G6.7a.1	Uncharacterized protein.	Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1.	0.734
C01A2.4	vps-2	C01A2.4.1	Y46G5A.12.1	Uncharacterized protein.	Related to yeast Vacuolar Protein Sorting factor.	0.968
C01A2.4	vps-20	C01A2.4.1	Y65B4A.3.1	Uncharacterized protein.	Related to yeast Vacuolar Protein Sorting factor.	0.745
C01A2.4	vps-24	C01A2.4.1	T27F7.1.2	Uncharacterized protein.	Related to yeast Vacuolar Protein Sorting factor.	0.865
C01A2.4	vps-60	C01A2.4.1	F41E6.9.1	Uncharacterized protein.	Related to yeast Vacuolar Protein Sorting factor.	0.549
C14E2.6	T08B1.4	C14E2.6.1	T08B1.4b.1	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.456
C14E2.6	Y110A7A.7	C14E2.6.1	Y110A7A.7.1	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.459
C14E2.6	Y51A2B.4	C14E2.6.1	Y51A2B.4.1	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.473
F28H7.3	B0035.13	F28H7.3.1	B0035.13.2	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.552
F28H7.3	T21H3.1	F28H7.3.1	T21H3.1a.1	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.419
F28H7.3	Y49E10.18	F28H7.3.1	Y49E10.18.1	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.432
H41C03.2	T08B1.4	H41C03.2.1	T08B1.4b.1	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.497
H41C03.2	Y110A7A.7	H41C03.2.1	Y110A7A.7.1	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.500
H41C03.2	Y51A2B.4	H41C03.2.1	Y51A2B.4.1	Lipase_3 domain-containing protein.	Lipase_3 domain-containing protein.	0.510
R12C12.5	C01A2.4	R12C12.5.1	C01A2.4.1	Uncharacterized protein.	Uncharacterized protein.	0.808
R12C12.5	T24B8.2	R12C12.5.1	T24B8.2.1	Uncharacterized protein.	Charged Multivesicular Body Protein homolog.	0.961