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| | dnc-2 | Probable dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. May play a role in synapse formation during brain development (By similarity); Belongs to the dynactin subunit 2 family. (331 aa) |
| | dli-1 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (443 aa) |
| | klp-16 | Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (587 aa) |
| | C49H3.16 | BPTI/Kunitz inhibitor domain-containing protein. (206 aa) |
| | arp-11 | Actin-Related Proteins; Belongs to the actin family. (384 aa) |
| | unc-104 | Kinesin-like protein unc-104; Motor protein involved in microtubule-associated anterograde transport. Regulates the transport of synaptic vesicle precursors in the axon of DA motor neurons. Regulates the polarized sorting of axonal proteins. Essential for the transport of synaptic components during the synaptic remodeling of the DD motor neuron, probably downstream of cdk-5 and/or pct-1/cyy-1 complex. Required for the anterograde transport of neuropeptide-containing dense core vesicles along axons. Involved in necrotic cell death. Belongs to the TRAFAC class myosin-kinesin ATPase super [...] (1628 aa) |
| | dylt-2 | DYnein Light chain (Tctex type). (123 aa) |
| | cap-1 | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (282 aa) |
| | xbx-1 | X-BoX promoter element regulated. (370 aa) |
| | kap-1 | Kinesin-Associated Protein. (696 aa) |
| | mei-2 | Meiotic spindle formation protein 2; Forms a heterodimeric complex in conjunction with mei-1 which severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. May act to target mei-1 within the cell. Required specifically for meiotic spindle formation in the female germline. (280 aa) |
| | gip-1 | Gamma-tubulin complex component. (963 aa) |
| | air-1 | Protein kinase domain-containing protein. (326 aa) |
| | klp-7 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa) |
| | vab-8 | Kinesin-like protein vab-8; Required for posterior migration of cells and axon growth cones during nervous system assembly. [Isoform b]: Specifically required for CAN cell migration. (1066 aa) |
| | klp-15 | Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (587 aa) |
| | osm-3 | Osmotic avoidance abnormal protein 3; Kinesin motor protein which is required for the anterograde intraflagellar transport (IFT) along the middle segment of the sensory neuron cilia together with the kinesin II motor complex (composed of klp-11, klp-20 and kap-1) and on its own, is required for IFT along the distal segment. In addition, regulates the length of cilia. May have a role during neurogenesis and axonal transport. (699 aa) |
| | zen-4 | Kinesin-like protein. (787 aa) |
| | cap-2 | F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (270 aa) |
| | dlc-2 | Probable dynein light chain 2, cytoplasmic; Acts as one of several non-catalytic accessory components of a dynein complex; Belongs to the dynein light chain family. (90 aa) |
| | klc-1 | TPR_REGION domain-containing protein. (536 aa) |
| | unc-116 | Kinesin heavy chain; Microtubule-dependent motor protein required for organelle transport. Plays a role in endosome transport. Required for the transport of mitochondria along the axon of motor neurons. Involved in the nuclear migration of hyp7 hypodermal precursor cells. Required for the formation of dendritic branches of PVD sensory neurons. In non-ciliated neurons such as the PVD and PHC neurons, required for the organization of minus-end out microtubules in dendrites. Involved in the localization of unc-33 to neurites. (815 aa) |
| | klp-18 | Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (932 aa) |
| | kin-4 | Protein KINase. (1831 aa) |
| | klc-2 | Kinesin light chain; Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport (Probable). The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (Probable). Recruits unc-83 (within the unc-83-unc-84 LINC complex) to the nuclear envelope during nuclear migration to mediate the link between the nuclear envelope and the microtubule cytoskeleton in hypodermal precursor cells. (540 aa) |
| | dlc-5 | Dynein Light Chain. (186 aa) |
| | dnc-5 | DyNactin Complex component. (184 aa) |
| | dnc-6 | Dynactin subunit 6; Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily. (180 aa) |
| | arp-1 | Actin-Related Proteins; Belongs to the actin family. (374 aa) |
| | nol-6 | Nucleolar protein 6. (1058 aa) |
| | klp-20 | Kinesin-like protein klp-20; Component of the kinesin II motor complex (composed of kap-1 and the heterodimeric motor proteins klp-11 and klp-20) which is required for intraflagellar transport (IFT). Heterodimerizes with klp-11 to form a 'processive' molecular motor upon IFT cargo binding, which, within the kinesin II motor complex, binds to and moves along microtubules in a unidirectional manner (without dissociation of the heterodimer), and in turn, is responsible for the IFT of cargo. Specifically, the kinesin II motor complex, together with the kinesin motor protein osm-3 moves alo [...] (646 aa) |
| | Y50C1A.2 | Uncharacterized protein. (406 aa) |
| | klp-19 | Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1083 aa) |
| | icp-1 | INCENP_ARK-bind domain-containing protein. (622 aa) |
| | dlc-4 | Dynein light chain. (129 aa) |
| | dlc-3 | Dynein light chain. (129 aa) |
| | dnc-3 | DyNactin Complex component. (171 aa) |
| | dhc-4 | DHC_N2 domain-containing protein. (2727 aa) |
| | klp-17 | Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (471 aa) |
| | dlc-1 | Dynein light chain 1, cytoplasmic; Acts as a non-catalytic accessory component of a dynein complex (By similarity). Part of a complex with bicd-1 and egal-1, which is recruited to the nuclear envelope by unc-83, where in turn, it recruits dynein to the nuclear surface and regulates nuclear migrations in hypodermal precursor cells. Probably within a dynein motor complex, plays a role in the cell fate specification of the germline and oogenesis. In particular, it inhibits germ cell proliferation. Regulates the function and localization of the RNA-binding protein fbf- 2 in the germline. P [...] (89 aa) |
| | dyrb-1 | Dynein light chain roadblock; Belongs to the GAMAD family. (95 aa) |
| | dhc-1 | Dynein heavy chain, cytoplasmic; Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules (By similarity). Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity). May play a role in nuclear migration in hypodermal precursor cells. May be involved in the transport of synaptic vesicle components towards the axon of the DA motor neuron. This function may involve the regulation of dynein by pct-1 and/or cdk-5. Involved in the formation of synapses in the dorsal regi [...] (4568 aa) |
| | klp-3 | Kinesin-like protein klp-3. (598 aa) |
| | dylt-3 | DYnein Light chain (Tctex type). (148 aa) |
| | klp-4 | Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1610 aa) |
| | F47G4.5 | Uncharacterized protein. (280 aa) |
| | lis-1 | Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as nuclear migration during cell division. Part of a complex with nud-2, which is recruited to the nuclear envelope by unc-83, where, in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells. Plays a role in GABAergic synaptic vesicle localization in [...] (404 aa) |
| | mei-1 | Meiotic spindle formation protein mei-1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. Required specifically for meiotic spindle formation in the female germline; the presence of this protein is inimical to the formation of mitotic spindles. In body wall muscles, regulates organization of myosin thick filaments. (475 aa) |
| | klp-12 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1605 aa) |
| | klp-6 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (928 aa) |
| | nud-2 | Protein nud-2; Part of a complex with lis-1, which is recruited to the nuclear envelope by unc-83, where, in turn, it recruits dynein to the nuclear surface and regulates nuclear migration in hypodermal precursor cells. Plays a role in GABAergic synaptic vesicle localization in the ventral nerve cord ; Belongs to the nudE family. (293 aa) |
| | bub-1 | Mitotic checkpoint serine/threonine-protein kinase bub-1; Serine/threonine-protein kinase essential for spindle- assembly checkpoint signaling. Plays a key role in the recruitment of the checkpoint proteins bub-3, mdf-1 and mdf-2 to unattached kinetochores. mdf-1 recruitment is independent of bub-1 kinase activity. Has a role in the correct kinetochore localization of the spindly-like protein spdl-1. In addition, during meiotic anaphase I, controls the recruitment of hcp- 1/2 and klp-19 to the ring-shaped domain formed between chromosomes. Involved in chromosome alignment, chromosome h [...] (987 aa) |
| | kca-1 | Kinesin 1 cargo adaptor alternative variant a. (407 aa) |
| | ZC262.7 | Uncharacterized protein. (171 aa) |
| | dnc-1 | CAP-Gly domain-containing protein. (1351 aa) |
| | F47G4.4 | Uncharacterized protein. (722 aa) |
| | ift-81 | IFT81_CH domain-containing protein. (638 aa) |
| | F31F6.3 | Uncharacterized protein. (285 aa) |
| | F31F6.2 | Uncharacterized protein. (298 aa) |
| | F31F6.1 | Uncharacterized protein. (365 aa) |
| | ttll-9 | Probable tubulin polyglutamylase ttll-9; Polyglutamylase that forms polyglutamate side chains on tubulin (By similarity). Acts when complexed with other proteins (Probable). Appears to be dispensable for polar spindle formation in dividing embryonic cells, for cilia-dependent osmotic avoidance and for male mating behavior. Probably by regulating microtubule stability via the glutamylation of tubulin, regulates PLM axon developmental growth. (417 aa) |
| | klp-13 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (691 aa) |
| | klp-11 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (782 aa) |
| | ift-74 | IFT (Chlamydomonas IntraFlagellar Transport) homolog. (624 aa) |
| | spas-1 | Probable spastin homolog spas-1; Severs microtubules, probably in an ATP-dependent fashion. Belongs to the AAA ATPase family. Spastin subfamily. (512 aa) |
| | dnc-4 | DyNactin Complex component. (413 aa) |
| | C27C12.3 | Uncharacterized protein. (400 aa) |
| | C27F2.1 | WD Repeat protein. (673 aa) |
| | che-3 | Cytoplasmic dynein 2 heavy chain 1; Functions as a motor for intraflagellar retrograde transport in chemosensory neurons. Functions in cilia biogenesis. Belongs to the dynein heavy chain family. (4171 aa) |
| | dylt-1 | DYnein Light chain (Tctex type). (106 aa) |
| | F11A10.5 | Protein ST7 homolog. (536 aa) |
| | dyci-1 | WD_REPEATS_REGION domain-containing protein. (643 aa) |
| | air-2 | Aurora/IPL1-related protein kinase 2; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation. Required for histone H3 phosphorylation during segregation of homologous chromosomes in meiosis and mitosis. Required for histone H3 'Ser- 10' phosphorylation. Phosphorylates tlk-1 at 'Ser-634', which enhances its activity. Phosphorylates zen-4 at 'Ser- 680'. Required f [...] (305 aa) |
| | dhc-3 | Dynein Heavy Chain. (3275 aa) |
