Your Input: | |
| | vps-20 | Related to yeast Vacuolar Protein Sorting factor. (208 aa) |
| | marc-5 | RING-CH-type domain-containing protein. (470 aa) |
| | Y54G2A.45 | Lipase_3 domain-containing protein. (337 aa) |
| | Y51H4A.5 | Lipase_3 domain-containing protein. (329 aa) |
| | spe-48 | UBA domain-containing protein. (337 aa) |
| | Y51A2B.4 | Lipase_3 domain-containing protein. (345 aa) |
| | Y49E10.18 | Lipase_3 domain-containing protein. (335 aa) |
| | rab-35 | RAB family. (209 aa) |
| | Y49E10.16 | Lipase_3 domain-containing protein. (327 aa) |
| | B0035.13 | Lipase_3 domain-containing protein. (297 aa) |
| | emc-5 | EMC Endoplasmic Membrane protein Complex (Yeast EMC) homolog. (144 aa) |
| | B0334.4 | PRELI/MSF1 domain-containing protein. (210 aa) |
| | B0334.5 | Uncharacterized protein. (420 aa) |
| | C01A2.4 | Uncharacterized protein. (207 aa) |
| | lmp-1 | LAMP family protein lmp-1; Belongs to the LAMP family. (237 aa) |
| | C05D11.1 | Uncharacterized protein C05D11.1. (995 aa) |
| | snx-1 | PX domain-containing protein. (472 aa) |
| | mvb-12 | MVB (Yeast MultiVesicular Body sorting factor) related. (277 aa) |
| | C06A6.4 | M20_dimer domain-containing protein. (411 aa) |
| | lmtr-3 | Late endosomal/lysosomal adaptor, Mapk (MAPK) and mToR (MTOR) activator homolog. (145 aa) |
| | hgrs-1 | Hepatocyte Growth factor-Regulated TK Substrate (HRS) family. (729 aa) |
| | tsg-101 | Tumor Susceptibility Gene homolog. (425 aa) |
| | C10C5.3 | M20_dimer domain-containing protein. (399 aa) |
| | C10C5.4 | M20_dimer domain-containing protein. (397 aa) |
| | C10C5.5 | M20_dimer domain-containing protein. (397 aa) |
| | C14E2.6 | Lipase_3 domain-containing protein. (194 aa) |
| | ocrl-1 | Rho-GAP domain-containing protein. (768 aa) |
| | maa-1 | ACB domain-containing protein. (266 aa) |
| | rap-2 | RAP homolog (Vertebrate Rap GTPase family). (181 aa) |
| | vps-22 | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (269 aa) |
| | C27F2.9 | JmjC domain-containing protein. (260 aa) |
| | C34B7.2 | SAC domain-containing protein. (905 aa) |
| | gop-1 | Protein CLEC16A homolog; Regulator of mitophagy. (892 aa) |
| | stam-1 | Signal transducing adapter molecule 1; Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1. (457 aa) |
| | C39B5.14 | Lipase_3 domain-containing protein. (329 aa) |
| | C40H1.2 | Uncharacterized protein C40H1.2. (208 aa) |
| | C40H1.8 | Lipase_3 domain-containing protein. (342 aa) |
| | C40H1.9 | Lipase_3 domain-containing protein. (349 aa) |
| | marc-4 | RING-CH-type domain-containing protein. (317 aa) |
| | marc-4-2 | Uncharacterized protein. (73 aa) |
| | drn-1 | GTP-binding protein drn-1; Displays low GTPase activity and exists predominantly in the GTP-bound form (By similarity). Together with epac-1, may regulate acetylcholine release at the neuromuscular junctions probably downstream of G-protein gsa-1 and adenylate cyclase acy-1. (219 aa) |
| | vps-32.1 | Related to yeast Vacuolar Protein Sorting factor. (221 aa) |
| | CD4.11 | Uncharacterized protein. (496 aa) |
| | vps-37 | VPS37 C-terminal domain-containing protein. (234 aa) |
| | aka-1 | FYVE-type domain-containing protein. (1284 aa) |
| | rab-8 | RAB family. (211 aa) |
| | mon-2 | Monensin-resistant homolog 2; May be required for traffic between late Golgi and early endosomes. (1648 aa) |
| | F13H10.3 | Sodium-coupled neutral amino acid transporter 9 homolog; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. (617 aa) |
| | vps-36 | GLUE N-terminal domain-containing protein. (383 aa) |
| | snx-17 | Sorting nexin-17 homolog; Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)). (540 aa) |
| | rme-8 | J domain-containing protein. (2279 aa) |
| | mrp-6 | Uncharacterized protein. (1415 aa) |
| | did-2 | Doa4-Independent Degradation, homologous to yeast Did2. (205 aa) |
| | F25A2.1 | Lipase_3 domain-containing protein. (290 aa) |
| | ehbp-1 | EH (Eps-15-homology) domain Binding Protein family. (901 aa) |
| | rab-5 | RAB family. (208 aa) |
| | F28H7.3 | Lipase_3 domain-containing protein. (294 aa) |
| | F33G12.3 | Uncharacterized protein. (403 aa) |
| | F40E10.6 | Uncharacterized protein. (398 aa) |
| | vps-60 | Related to yeast Vacuolar Protein Sorting factor. (217 aa) |
| | F41H10.4 | Uncharacterized protein. (575 aa) |
| | urm-1 | Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress spec [...] (100 aa) |
| | sdpn-1 | SynDaPiN (Synaptic dynamin binding protein) homolog. (495 aa) |
| | F46G10.4 | Lipase_3 domain-containing protein. (336 aa) |
| | sorf-2 | Suppressor of organelle fusion 2; Together with sorf-1 negatively regulates the levels of phosphatidylinositol 3-phosphate (PtdIns3P) to enable the conversion of early endosomes to late endosomes. Binds to sorf-1 and the sorf-1-sorf- 2 complex likely acts through bec-1, a non-catalytic subunit of phosphatidylinositol 3-kinase (PI3K), to suppress PI3K activity, thereby negatively regulating endosomal PtdIns3P levels. Belongs to the WD repeat WDR81 family. (1422 aa) |
| | ubxn-6 | UBX domain-containing protein 6; Probably acts as an adapter for ATPase cdc-48.1 and/or cdc- 48.2, conferring substrate specificity. Involved in the lysosomal clearance of cellular material in diet restricted conditions. (437 aa) |
| | H41C03.2 | Lipase_3 domain-containing protein. (356 aa) |
| | K03H6.2 | Lipase_3 domain-containing protein. (339 aa) |
| | K08B12.1 | Lipase_3 domain-containing protein. (374 aa) |
| | hrg-1 | Heme transporter hrg-1; Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment. Belongs to the HRG family. (194 aa) |
| | R12C12.5 | Uncharacterized protein. (236 aa) |
| | R12C12.6 | Uncharacterized protein. (261 aa) |
| | lmtr-5 | Late endosomal/lysosomal adaptor, Mapk (MAPK) and mToR (MTOR) activator homolog. (95 aa) |
| | lst-2 | Lateral signaling target protein 2; Negative regulator of epidermal growth factor receptor (EGFR) signaling; Belongs to the lst-2 family. (661 aa) |
| | T08B1.4 | Lipase_3 domain-containing protein. (342 aa) |
| | rme-2 | Receptor Mediated Endocytosis. (925 aa) |
| | mam-4 | MAM (Meprin, A5-protein, PTPmu) domain protein. (588 aa) |
| | T21H3.1 | Lipase_3 domain-containing protein. (305 aa) |
| | rab-10 | Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for basolateral endocytic recycling, the return of macromolecules and fluid from endosomes to the plasma membrane, in polarized epithelial cells of the intestine upstream of rm [...] (201 aa) |
| | T24B8.2 | Charged Multivesicular Body Protein homolog. (411 aa) |
| | vps-24 | Related to yeast Vacuolar Protein Sorting factor. (208 aa) |
| | vps-25 | Related to yeast Vacuolar Protein Sorting factor. (183 aa) |
| | rab-7 | RAB family. (209 aa) |
| | snx-3 | PX domain-containing protein. (162 aa) |
| | rme-1 | Receptor Mediated Endocytosis; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (791 aa) |
| | Y110A7A.7 | Lipase_3 domain-containing protein. (312 aa) |
| | arf-6 | ADP-Ribosylation Factor related; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | cnt-1 | Arf-GAP with ANK repeat and PH domain-containing protein cnt-1; GTPase-activating protein for the ADP ribosylation factor family (Probable). Regulates endosome recycling downstream of rab-10 and upstream of arf-6. (826 aa) |
| | Y25C1A.7 | Yip1 domain-containing protein. (414 aa) |
| | vps-2 | Related to yeast Vacuolar Protein Sorting factor. (237 aa) |
| | sorf-1 | Suppressor of organelle fusion 1; Together with sorf-2 negatively regulates the levels of phosphatidylinositol 3-phosphate (PtdIns3P) to enable the conversion of early endosomes to late endosomes. Binds to sorf-2 and the sorf-1-sorf- 2 complex likely acts through bec-1, a non-catalytic subunit of phosphatidylinositol 3-kinase (PI3K), to suppress PI3K activity, thereby negatively regulating endosomal PtdIns3P levels. Belongs to the WD repeat WDR91 family. (239 aa) |
| | ZK262.3 | Lipase ZK262.3; Probable lipase; Belongs to the AB hydrolase superfamily. Lipase family. (353 aa) |
| | ZK262.2 | Lipase_3 domain-containing protein. (353 aa) |
| | lmtr-2 | Ragulator complex protein LAMTOR2 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. May activate the TOR signaling cascade in response to amino acids; Belongs to the GAMAD family. (124 aa) |
| | vps-28 | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex, a regulator of vesicular trafficking process; Belongs to the VPS28 family. (210 aa) |
