STRINGSTRING
tbcd-1 tbcd-1 unc-70 unc-70 kqt-2 kqt-2 Y44A6C.2 Y44A6C.2 kqt-3 kqt-3 oig-5 oig-5 tln-1 tln-1 pat-3 pat-3 let-23 let-23 lnkn-1 lnkn-1 unc-44 unc-44 sax-7 sax-7 kqt-1 kqt-1 C38D9.8 C38D9.8 glp-1 glp-1 sdz-16 sdz-16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tbcd-1Tubulin-specific chaperone D; Tubulin-folding protein; involved in the first step of the tubulin folding pathway (By similarity). Plays a role in microtubule polymerization ; Belongs to the TBCD family. (1232 aa)
unc-70Spectrin beta chain; Belongs to the spectrin family. (2326 aa)
kqt-2Ion_trans domain-containing protein; Belongs to the potassium channel family. (695 aa)
Y44A6C.2Uncharacterized protein. (354 aa)
kqt-3Potassium channel, KvQLT family; Belongs to the potassium channel family. (621 aa)
oig-5Ig-like domain-containing protein. (164 aa)
tln-1Talin. (2553 aa)
pat-3Integrin beta pat-3; Integrin alpha ina-1/beta pat-3 is a receptor for laminin. Integrin alpha pat-2/beta pat-3 recognizes the sequence R-G-D in its ligands (Probable). Plays a role in cell migration, morphogenesis and probably in cell-cell interactions. During gonad morphogenesis, involved in distal tip cell (DTC)-mediated guidance of gonad elongation, in maintaining their sharp tapering morphology and in their migration. Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Involved in the assembly of dense bodies and M line [...] (809 aa)
let-23Receptor tyrosine-protein kinase let-23; Tyrosine-protein kinase receptor which, upon binding ligand lin-3, activates 2 signaling cascades: the let-60/Ras and MAP kinase signaling pathway and the let-60-independent phospholipase C-mediated Ca(2+) signaling pathway. Each pathway regulates distinct functions. By activating let-60/Ras, regulates larval development, induction of vulva cell precursors during vulva development, male spicule formation and posterior development of the epidermis. Probably by activating phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signalin [...] (1335 aa)
lnkn-1Protein linkin; Probable cell adhesion protein involved in gonadal cell migration. (599 aa)
unc-44Uncharacterized protein. (6994 aa)
sax-7Fibronectin type-III domain-containing protein. (1331 aa)
kqt-1Potassium channel, KvQLT family; Belongs to the potassium channel family. (740 aa)
C38D9.8Uncharacterized protein. (344 aa)
glp-1Protein glp-1; Involved in the specification of the cell fates of the blastomeres, ABa and APa. Proper signaling by glp-1 induces ABa descendants to produce anterior pharyngeal cells, and APa descendants to adopt a different fate. Contributes to the establishment of the dorsal-ventral axis in early embryos. Regulates germ cell mitotic proliferation probably by regulating MAP kinase phosphatase lip-1 expression. Plays a negative role in lifespan. (1295 aa)
sdz-16SKN-1 Dependent Zygotic transcript. (344 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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