STRINGSTRING
nmy-2 nmy-2 mlc-4 mlc-4 Y60A3A.9 Y60A3A.9 act-5 act-5 hum-6 hum-6 T05E7.3 T05E7.3 R148.5 R148.5 wip-1 wip-1 spe-26 spe-26 ate-1 ate-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nmy-2Non-muscle MYosin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2003 aa)
mlc-4Myosin regulatory light chain; Regulates myosin II activity and organization during embryo elongation. May be involved in the organization of mlc-5 into bundles. Required maternally for cytokinesis during meiosis and mitosis in the early embryo and for the establishment of embryonic anterior-posterior polarity. (172 aa)
Y60A3A.9GOLD domain-containing protein. (211 aa)
act-5ACTin. (375 aa)
hum-6Unconventional myosin heavy chain 6; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). (2098 aa)
T05E7.3Uncharacterized protein. (997 aa)
R148.5PID domain-containing protein. (528 aa)
wip-1WH2 domain-containing protein. (362 aa)
spe-26Spermatocyte protein spe-26; May play a role in the spermatocyte cytoskeleton, possibly interacting with actin. (570 aa)
ate-1Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Belongs to the R-transferase family. (485 aa)
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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