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| | ZK686.5 | Putative zinc finger protein ZK686.5. (263 aa) |
| | acl-3 | Tafazzin family protein; Belongs to the taffazin family. (284 aa) |
| | ZK809.3 | Uncharacterized protein. (210 aa) |
| | ZK938.3 | ATPase_AAA_core domain-containing protein. (660 aa) |
| | lpd-5 | LiPid Depleted. (176 aa) |
| | sco-1 | SCO (Yeast Suppressor of Cytochrome Oxidase deficiency) homolog. (312 aa) |
| | fog-3 | Anti_prolifrtn domain-containing protein. (263 aa) |
| | sdha-1 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (646 aa) |
| | C04F5.8 | Uncharacterized protein. (342 aa) |
| | atp-5 | ATP synthase subunit. (191 aa) |
| | sod-3 | Superoxide dismutase [Mn] 2, mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. (218 aa) |
| | C08D8.1 | Uncharacterized protein. (443 aa) |
| | nuo-1 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (479 aa) |
| | C14B9.10 | Uncharacterized protein. (60 aa) |
| | dct-1 | NIP3 homolog; Initiates apoptosis in a BH3-independent mechanism possibly by recruiting ced-3 to mitochondria and other cytoplasmic membranes. Has a role in lifespan and tumor growth. Required for the induction of mitophagy under stress conditions. Belongs to the NIP3 family. (221 aa) |
| | tomm-40 | Mitochondrial import receptor subunit TOM40 homolog; Channel-forming protein essential for import of protein precursors into mitochondria. Specifically required for nnt-1 accumulation in the mitochondria and may be involved in the secretion of daf-28/insulin from the mitochondria. Required for embryonic and larval development. (301 aa) |
| | C50F4.12 | Uncharacterized protein. (439 aa) |
| | C53B4.4 | Uncharacterized protein. (1362 aa) |
| | asg-2 | Probable ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism [...] (131 aa) |
| | cyc-1 | Cytochrome c domain-containing protein. (285 aa) |
| | C56A3.6 | Uncharacterized protein. (477 aa) |
| | akap-1 | KH domain-containing protein akap-1. (867 aa) |
| | slc-25A26 | SLC (SoLute Carrier) homolog; Belongs to the mitochondrial carrier (TC 2.A.29) family. (269 aa) |
| | eat-3 | Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (964 aa) |
| | wdr-23 | DDB1- and CUL4-associated factor 11 homolog; Involved in regulation of lifespan. Required for dopaminergic CEP neuron degeneration in response to Mn(2+). (571 aa) |
| | timm-17B.2 | Translocase, Inner Mitochondrial Membrane. (140 aa) |
| | timm-17B.1 | Probable mitochondrial import inner membrane translocase subunit tim-17B.1; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane; Belongs to the Tim17/Tim22/Tim23 family. (181 aa) |
| | F01F1.3 | Uncharacterized protein. (248 aa) |
| | asb-2 | ATP Synthase B homolog. (305 aa) |
| | sqrd-1 | Pyr_redox_2 domain-containing protein. (471 aa) |
| | cpt-5 | Carn_acyltransf domain-containing protein. (735 aa) |
| | sod-2 | Superoxide dismutase [Mn] 1, mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. (221 aa) |
| | dnj-9 | J domain-containing protein. (564 aa) |
| | fis-2 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (151 aa) |
| | timm-23 | Translocase, Inner Mitochondrial Membrane. (242 aa) |
| | romo-1 | (Reactive Oxygen species MOdulator) homolog. (82 aa) |
| | emre-1 | Essential MCU regulator, mitochondrial; Essential regulatory subunit of the mitochondrial calcium uniporter (mcu-1) channel, a protein that mediates calcium uptake into mitochondria; Belongs to the SMDT1/EMRE family. (90 aa) |
| | tomm-20 | Mitochondrial import receptor subunit TOM20 homolog; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins (By similarity). Together with tomm-22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore. (188 aa) |
| | ubq-1 | Ubiquitin-related; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degrad [...] (838 aa) |
| | cox-5B | Cytochrome OXidase assembly protein. (132 aa) |
| | atp-3 | ATP synthase subunit. (228 aa) |
| | F31D4.9 | Uncharacterized protein. (70 aa) |
| | F31D5.1 | Uncharacterized protein. (457 aa) |
| | F31D5.2 | Uncharacterized protein. (470 aa) |
| | F32B4.2 | Uncharacterized protein. (167 aa) |
| | coq-1 | COenzyme Q (Ubiquinone) biosynthesis; Belongs to the FPP/GGPP synthase family. (393 aa) |
| | immp-1 | Peptidase_S24 domain-containing protein. (132 aa) |
| | C25H3.9 | Uncharacterized protein. (186 aa) |
| | C27C12.4 | Uncharacterized protein. (450 aa) |
| | C35D10.5 | Uncharacterized protein. (244 aa) |
| | coq-8 | Atypical kinase coq-8, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: either acts as protein kinase that phosphorylates other proteins in the CoQ complex to stabilize their interactions or acts as a small molecule kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. (755 aa) |
| | atp-2 | ATP synthase subunit beta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] (538 aa) |
| | C47G2.3 | Mitochondrial import inner membrane translocase subunit tim-22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). (213 aa) |
| | gop-3 | SAM50-like protein gop-3; May play a role in the maintenance of the structure of mitochondrial cristae; Belongs to the SAM50/omp85 family. (434 aa) |
| | C34C12.8 | GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity). (237 aa) |
| | C34B2.8 | Uncharacterized protein. (171 aa) |
| | sdha-2 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (640 aa) |
| | C33A12.1 | Probable NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (150 aa) |
| | lgg-1 | Protein lgg-1; Ubiquitin-like modifier involved in the formation of autophagosomal vacuoles (autophagosomes). When lipidated mediates tethering between adjacent membranes and stimulates membrane fusion during autophagy. Recruits lipidated-lgg-2 to maturing autophagosomes. Acts in the aggrephagy pathway, which is the macroautophagic degradation of ubiquitinated protein aggregates, and preferentially interacts with autophagy proteins and substrates containing LIR motifs to mediate autophagosome formation and protein aggregate degradation. In particular, binds to components of the unc-51- [...] (123 aa) |
| | C32D5.12 | 3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (357 aa) |
| | haf-1 | HAlF transporter (PGP related). (677 aa) |
| | C30G7.3 | Uncharacterized protein. (301 aa) |
| | C47E12.2 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (306 aa) |
| | C43E11.12 | TFIIIC_sub6 domain-containing protein. (184 aa) |
| | C41G7.9 | Uncharacterized protein. (212 aa) |
| | C38C3.3 | Uncharacterized protein. (304 aa) |
| | amx-2 | Amino_oxidase domain-containing protein. (724 aa) |
| | B0495.9 | Uncharacterized protein B0495.9. (267 aa) |
| | B0554.5 | Uncharacterized protein. (468 aa) |
| | B0554.7 | Uncharacterized protein. (473 aa) |
| | hpo-18 | Uncharacterized protein. (54 aa) |
| | F32D8.5 | Uncharacterized protein. (227 aa) |
| | sdhd-1 | Putative succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (145 aa) |
| | coa-3 | Coiled-coil_56 domain-containing protein. (133 aa) |
| | asb-1 | ATP Synthase B homolog. (301 aa) |
| | F36D4.6 | Uncharacterized protein. (91 aa) |
| | F36G9.3 | Uncharacterized protein. (433 aa) |
| | F38A5.2 | Uncharacterized protein. (452 aa) |
| | mtx-1 | Metaxin-1 homolog; Involved in transport of proteins into the mitochondrion. Essential for embryonic development (By similarity); Belongs to the metaxin family. (312 aa) |
| | fis-1 | Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (143 aa) |
| | F42A8.1 | Uncharacterized protein F42A8.1. (370 aa) |
| | sdhb-1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (298 aa) |
| | F42G8.10 | Uncharacterized protein. (181 aa) |
| | isp-1 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (276 aa) |
| | slc-25A42 | SLC (SoLute Carrier) homolog; Belongs to the mitochondrial carrier (TC 2.A.29) family. (294 aa) |
| | oxa-1 | OXA mitochondrial inner membrane insertase homolog. (366 aa) |
| | F44E7.9 | Uncharacterized protein. (121 aa) |
| | F44G4.2 | Probable NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (160 aa) |
| | F45G2.8 | Mitochondrial import inner membrane translocase subunit tim-16; Regulates ATP-dependent protein translocation into the mitochondrial matrix; Belongs to the TIM16/PAM16 family. (136 aa) |
| | F45H10.2 | Uncharacterized protein. (90 aa) |
| | F45H10.3 | Uncharacterized protein. (168 aa) |
| | ttr-57 | TransThyretin-Related family domain. (89 aa) |
| | F48E3.4 | Peptidase S1 domain-containing protein. (279 aa) |
| | F49E10.4 | MIEAP domain-containing protein. (645 aa) |
| | dif-1 | Protein dif-1; Seems to play a role in the maintenance of tissue differentiation in the developing embryo, but not for its initiation. (312 aa) |
| | F52C6.2 | Ubiquitin-like domain-containing protein. (228 aa) |
| | F52C6.3 | Ubiquitin-like domain-containing protein. (197 aa) |
| | mpc-2 | Probable mitochondrial pyruvate carrier 2; May mediate the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (133 aa) |
| | F53F4.10 | Probable NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (239 aa) |
| | F54A3.5 | MICOS complex subunit Mic10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (105 aa) |
| | cox-6A | Cytochrome c oxidase subunit 6A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (128 aa) |
| | mff-2 | Mitochondrial Fission Factor. (161 aa) |
| | F56B3.11 | Uncharacterized protein. (213 aa) |
| | haf-3 | HAlF transporter (PGP related). (666 aa) |
| | F58F12.1 | ATP synthase subunit delta, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the c [...] (163 aa) |
| | letm-1 | LETM1 (Leucine zipper, EF-hand, TransMembrane mitochondrial protein) homolog. (784 aa) |
| | atp-1 | ATP synthase subunit alpha, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the [...] (538 aa) |
| | cox-11 | Cytochrome OXidase assembly protein. (260 aa) |
| | slc-25A32 | SLC (SoLute Carrier) homolog; Belongs to the mitochondrial carrier (TC 2.A.29) family. (296 aa) |
| | ant-1.3 | Mitochondrial adenine nucleotide translocase 1.3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa) |
| | mcu-1 | Calcium uniporter protein, mitochondrial; Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore- forming and calcium-conducting subunit (By similarity). Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways (By similarity). Required for rapid mitochondrial calcium uptake and mitochondrial reactive oxygen species (mtROS) production after wounding. (333 aa) |
| | moma-1 | MICOS complex subunit MIC27; Sustains mitochondrial morphology probably through maintaining cristae morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). (201 aa) |
| | K02F3.2 | Probable calcium-binding mitochondrial carrier K02F3.2; Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. (716 aa) |
| | vms-1 | Protein vms-1; Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Component of an evolutionarily conserved system for ubiquitin-mediated mitochondria-associated protein degradation (MAD) (By similarity). Dispensable for viability and growth but is required for protection against oxidative stress and for wild- type life span. (618 aa) |
| | asg-1 | Probable ATP synthase subunit g 1, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism [...] (131 aa) |
| | coq-6 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6; Belongs to the UbiH/COQ6 family. (451 aa) |
| | ucp-4 | UnCoupling Protein (Mitochondrial substrate carrier); Belongs to the mitochondrial carrier (TC 2.A.29) family. (324 aa) |
| | pdr-1 | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (386 aa) |
| | miro-1 | Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. (625 aa) |
| | gas-1 | Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (482 aa) |
| | K09E4.3 | Methyltransf_11 domain-containing protein. (313 aa) |
| | cpt-4 | Carn_acyltransf domain-containing protein. (748 aa) |
| | K11H12.8 | Uncharacterized protein; Belongs to the BI1 family. (342 aa) |
| | ymel-1 | ATP-dependent zinc metalloprotease YME1 homolog; ATP-dependent metalloprotease that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region (By similarity). Plays an important role in regulating mitochondrial morphology and function (By similarity); In the C-terminal section; belongs to the peptidase M41 family. (723 aa) |
| | M110.3 | RING-CH-type domain-containing protein. (189 aa) |
| | M153.2 | Uncharacterized protein. (458 aa) |
| | chch-3 | MICOS complex subunit MIC19; Plays a role in maintaining mitochondrial morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic19 subfamily. (169 aa) |
| | nduo-1 | NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (291 aa) |
| | atp-6 | ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (199 aa) |
| | nduo-2 | NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (282 aa) |
| | ctb-1 | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c (By similarity). Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (370 aa) |
| | nduo-4 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (409 aa) |
| | ctc-1 | Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (525 aa) |
| | ctc-2 | Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (231 aa) |
| | nduo-3 | NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (111 aa) |
| | nduo-5 | NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (527 aa) |
| | ndfl-4 | NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (77 aa) |
| | R04F11.5 | Uncharacterized protein. (185 aa) |
| | R05D3.6 | Putative ATP synthase subunit epsilon, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechan [...] (54 aa) |
| | vdac-1 | Probable voltage-dependent anion-selective channel; Forms a channel through the cell membrane that allows diffusion of small hydrophilic molecules. (283 aa) |
| | R07E3.4 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | R07E4.3 | Uncharacterized protein. (90 aa) |
| | pgam-5 | Serine/threonine-protein phosphatase Pgam5, mitochondrial; Displays phosphatase activity for serine/threonine residues. Has apparently no phosphoglycerate mutase activity (By similarity). Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (284 aa) |
| | klp-6 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (928 aa) |
| | ant-1.4 | Mitochondrial adenine nucleotide translocase 1.4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa) |
| | T02H6.11 | Uncharacterized protein. (130 aa) |
| | coq-4 | Ubiquinone biosynthesis protein coq-4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (231 aa) |
| | fndc-1 | FUN14 domain-containing protein fndc-1; Mitophagy receptor which plays a role in paternal mitochondria degradation in embryos after the two-cell stage. (138 aa) |
| | mev-1 | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). Mediates resistance to enteropathogenic E.coli infection. Belongs to the cytochrome b560 family. (182 aa) |
| | ced-9 | Apoptosis regulator ced-9; Plays a major role in programmed cell death (PCD, apoptosis). egl-1 binds to and directly inhibits the activity of ced-9, releasing the cell death activator ced-4 from a ced-9/ced-4 containing protein complex and allowing ced-4 to activate the cell-killing caspase ced-3. During larval development, required for the elimination of transient presynaptic components downstream of egl-1 and upstream of ced-4 and ced-3 apoptotic pathway. (280 aa) |
| | tin-44 | Probable mitochondrial import inner membrane translocase subunit tin-44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source. (425 aa) |
| | ucr-2.2 | Ubiquinol-Cytochrome c oxidoReductase complex. (422 aa) |
| | nuo-2 | Complex1_30kDa domain-containing protein; Belongs to the complex I 30 kDa subunit family. (268 aa) |
| | mtp-18 | Mitochondrial fission process protein 1; Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function leads to apoptosis (By similarity). Belongs to the MTFP1 family. (166 aa) |
| | immt-1 | MICOS complex subunit MIC60-1; Sustains mitochondrial morphology probably through maintaining cristae morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). (679 aa) |
| | dnj-21 | Mitochondrial import inner membrane translocase subunit TIM14; Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). (112 aa) |
| | T20H4.5 | Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (212 aa) |
| | scpl-4 | Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane; Belongs to the TIM50 family. (452 aa) |
| | T22D1.3 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (534 aa) |
| | ucr-2.3 | Peptidase_M16 domain-containing protein. (427 aa) |
| | phb-2 | Mitochondrial prohibitin complex protein 2; PHB proteins are essential during embryonic development and are required for somatic and germline differentiation in the larval gonad. A deficiency in PHB proteins results in altered mitochondrial biogenesis in body wall muscle cells. (294 aa) |
| | nduf-2.2 | Complex1_49kDa domain-containing protein; Belongs to the complex I 49 kDa subunit family. (474 aa) |
| | ant-1.1 | Adenine Nucleotide Translocator; Belongs to the mitochondrial carrier (TC 2.A.29) family. (300 aa) |
| | T27E9.2 | Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (75 aa) |
| | asic-2 | Degenerin-like protein asic-2. (545 aa) |
| | ucr-2.1 | Ubiquinol-Cytochrome c oxidoReductase complex. (424 aa) |
| | cpt-6 | Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (746 aa) |
| | nuo-6 | NADH Ubiquinone Oxidoreductase. (172 aa) |
| | cisd-1 | ZnF_CDGSH domain-containing protein. (134 aa) |
| | ant-1.2 | Adenine Nucleotide Translocator; Belongs to the mitochondrial carrier (TC 2.A.29) family. (300 aa) |
| | W03F9.4 | Carn_acyltransf domain-containing protein. (746 aa) |
| | W04C9.2 | MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (102 aa) |
| | immt-2 | MICOS complex subunit MIC60-2; Sustains mitochondrial morphology probably through maintaining cristae morphology. May act as a component of the MICOS complex, a large protein complex of the mitochondria (By similarity). (654 aa) |
| | cox-4 | Cytochrome OXidase assembly protein. (175 aa) |
| | nduf-7 | Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (199 aa) |
| | tomm-22 | Mitochondrial import receptor subunit TOM22 homolog; Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins (By similarity). Together with the peripheral receptor tomm-20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore. (109 aa) |
| | Y108F1.1 | annotation not available (238 aa) |
| | tyms-1 | Thymidylat_synt domain-containing protein. (312 aa) |
| | Y11D7A.3 | Uncharacterized protein. (475 aa) |
| | hsp-60 | Chaperonin homolog Hsp-60, mitochondrial; Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (By similarity). (568 aa) |
| | Y32H12A.7 | ABC1 domain-containing protein. (580 aa) |
| | Y37A1A.2 | Uncharacterized protein. (464 aa) |
| | cox-5A | Cytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (174 aa) |
| | phb-1 | Mitochondrial prohibitin complex protein 1; PHB proteins are essential during embryonic development and are required for somatic and germline differentiation in the larval gonad. A deficiency in PHB proteins results in altered mitochondrial biogenesis in body wall muscle cells. (275 aa) |
| | ppgn-1 | AAA domain-containing protein. (747 aa) |
| | Y39A1A.20 | Uncharacterized protein. (113 aa) |
| | Y39A1A.21 | ATP synthase subunit C lysine N-methyltransferase; Mitochondrial protein-lysine N-methyltransferase that trimethylates ATP synthase subunit C. Trimethylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration. (190 aa) |
| | Y39B6A.27 | Uncharacterized protein. (473 aa) |
| | Y39B6A.29 | Uncharacterized protein. (453 aa) |
| | Y39B6A.34 | COA8 family protein Y39B6A.34, mitochondrial; May be required for cytochrome c complex (COX) assembly and function, COX being the terminal component of the mitochondrial respiratory chain; Belongs to the COA8 family. (142 aa) |
| | Y39D8A.1 | Uncharacterized protein. (468 aa) |
| | slc-25A46 | SLC (SoLute Carrier) homolog; Belongs to the mitochondrial carrier (TC 2.A.29) family. (500 aa) |
| | acdh-11 | Acyl-CoA dehydrogenase family member 11; Promotes adaption to elevated temperatures by regulating expression of the lipid desaturase, fat-7. Binds selectively and with high affinity to fatty acids with chain lengths from C10 to C12 and prevents them from activating fat-7 expression mediated by the nuclear hormone receptor nhr-49, leading to low levels of membrane lipid desaturation and membrane fluidity for adaption to heat. (617 aa) |
| | nuo-5 | NADH Ubiquinone Oxidoreductase; Belongs to the complex I 75 kDa subunit family. (729 aa) |
| | cpt-1 | Carnitine Palmitoyl Transferase; Belongs to the carnitine/choline acetyltransferase family. (779 aa) |
| | Y47C4A.1 | Uncharacterized protein. (408 aa) |
| | spg-7 | AFG3-like protein spg-7; Acts as a component of the m-AAA protease complex which is an ATP-dependent metalloprotease mediating degradation of non-assembled mitochondrial inner membrane proteins (By similarity). The complex is necessary for the assembly of mitochondrial respiratory chain and ATPase complexes (By similarity). Functions both in post-translational assembly and in the turnover of mistranslated or misfolded polypeptides. Plays a role in male tail tip morphogenesis. In the C-terminal section; belongs to the peptidase M41 family. (782 aa) |
| | Y48E1B.17 | PIG-P domain-containing protein. (141 aa) |
| | cpt-3 | Carn_acyltransf domain-containing protein. (722 aa) |
| | Y51H1A.3 | Uncharacterized protein. (215 aa) |
| | plep-1 | PLugged Excretory Pore. (456 aa) |
| | Y52E8A.6 | Uncharacterized protein. (436 aa) |
| | Y53F4B.14 | Uncharacterized protein. (90 aa) |
| | Y53G8AL.2 | NAD(P)-bd_dom domain-containing protein. (431 aa) |
| | nduf-5 | NADH Ubiquinone oxidoreductase Fe-S protein. (121 aa) |
| | immp-2 | Inner Mitochondrial Membrane Protease. (152 aa) |
| | cox-18 | Cytochrome OXidase assembly protein. (317 aa) |
| | coq-3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (268 aa) |
| | nuo-3 | NADH Ubiquinone Oxidoreductase. (131 aa) |
| | Y63D3A.7 | L51_S25_CI-B8 domain-containing protein. (92 aa) |
| | tin-10 | Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (Probable). (86 aa) |
| | Y67D2.2 | Ubiquitin carboxyl-terminal hydrolase. (474 aa) |
| | micu-1 | Calcium uptake protein 1 homolog, mitochondrial; Key regulator of mitochondrial calcium uniporter (MCU). (534 aa) |
| | hsd-1 | 3Beta_HSD domain-containing protein. (462 aa) |
| | Y71F9B.2 | Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. (321 aa) |
| | cox-6B | Cytochrome OXidase assembly protein. (121 aa) |
| | Y82E9BR.3 | ATP synthase lipid-binding protein, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism [...] (116 aa) |
| | Y94A7B.11 | Uncharacterized protein. (69 aa) |
| | Y9C9A.16 | Pyr_redox_2 domain-containing protein. (422 aa) |
| | ZC262.5 | Putative ATP synthase subunit epsilon, mitochondrial. (54 aa) |
| | clk-1 | 5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone- independent manner; Belongs to the COQ7 family. (187 aa) |
| | hsd-3 | 3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (359 aa) |
| | hsd-2 | 3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (374 aa) |
| | mtx-2 | Metaxin-2 homolog. (260 aa) |
| | fzo-1 | Transmembrane GTPase fzo-1; Probable transmembrane GTPase (By similarity). Mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission (By similarity); Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily. (774 aa) |
| | tomm-70 | Mitochondrial import receptor subunit tomm-70; Receptor that accelerates the import of all mitochondrial precursor proteins; Belongs to the Tom70 family. (554 aa) |
| | ZK470.1 | Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family. (180 aa) |
| | lsm-7 | Sm domain-containing protein. (104 aa) |
| | ZK6.6 | Uncharacterized protein. (482 aa) |
| | ZK6.8 | Uncharacterized protein. (488 aa) |
| | tomm-7 | Mitochondrial import receptor subunit TOM7 homolog; Belongs to the Tom7 family. (58 aa) |
| | coq-5 | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (285 aa) |
| | ZK686.2 | Putative ATP-dependent RNA helicase ZK686.2; Probable ATP-binding RNA helicase; Belongs to the DEAD box helicase family. (593 aa) |
