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| bub-1 | Mitotic checkpoint serine/threonine-protein kinase bub-1; Serine/threonine-protein kinase essential for spindle- assembly checkpoint signaling. Plays a key role in the recruitment of the checkpoint proteins bub-3, mdf-1 and mdf-2 to unattached kinetochores. mdf-1 recruitment is independent of bub-1 kinase activity. Has a role in the correct kinetochore localization of the spindly-like protein spdl-1. In addition, during meiotic anaphase I, controls the recruitment of hcp- 1/2 and klp-19 to the ring-shaped domain formed between chromosomes. Involved in chromosome alignment, chromosome h [...] (987 aa) | ||||
| air-2 | Aurora/IPL1-related protein kinase 2; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation. Required for histone H3 phosphorylation during segregation of homologous chromosomes in meiosis and mitosis. Required for histone H3 'Ser- 10' phosphorylation. Phosphorylates tlk-1 at 'Ser-634', which enhances its activity. Phosphorylates zen-4 at 'Ser- 680'. Required f [...] (305 aa) | ||||
| F31F6.3 | Uncharacterized protein. (285 aa) | ||||
| air-1 | Protein kinase domain-containing protein. (326 aa) | ||||
| C27C12.3 | Uncharacterized protein. (400 aa) | ||||
| F31F6.1 | Uncharacterized protein. (365 aa) | ||||
| F31F6.2 | Uncharacterized protein. (298 aa) | ||||
| icp-1 | INCENP_ARK-bind domain-containing protein. (622 aa) | ||||